{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T01:24:00Z","timestamp":1778894640544,"version":"3.51.4"},"reference-count":25,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,1,18]],"date-time":"2016-01-18T00:00:00Z","timestamp":1453075200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Sleep Research"],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>A 75\u2010year\u2010old man complained of excessive daytime sleepiness (<jats:styled-content style=\"fixed-case\">EDS<\/jats:styled-content>), difficulty falling asleep and nocturnal agitation during sleep. Restless legs syndrome (<jats:styled-content style=\"fixed-case\">RLS<\/jats:styled-content>) was diagnosed and treated. Because of persistent <jats:styled-content style=\"fixed-case\">EDS<\/jats:styled-content>, snoring and nycturia, a nocturnal polysomnography (<jats:styled-content style=\"fixed-case\">PSG<\/jats:styled-content>) was performed. <jats:styled-content style=\"fixed-case\">PSG<\/jats:styled-content> showed high sleep fragmentation related to a moderate to severe obstructive sleep apnea syndrome. Continuous positive airway pressure treatment (<jats:styled-content style=\"fixed-case\">CPAP<\/jats:styled-content>) was proposed. Because of the persistence of abnormal nocturnal behaviours, characterized by screaming, punching and falling out of bed, a video\u2010<jats:styled-content style=\"fixed-case\">PSG<\/jats:styled-content> with <jats:styled-content style=\"fixed-case\">CPAP<\/jats:styled-content> treatment was performed. The recording showed typical chin electromyography (<jats:styled-content style=\"fixed-case\">EMG<\/jats:styled-content>) activity increase associated with violent movements during rapid eye movement (<jats:styled-content style=\"fixed-case\">REM<\/jats:styled-content>) sleep, suggesting <jats:styled-content style=\"fixed-case\">REM<\/jats:styled-content> sleep behaviour disorders (<jats:styled-content style=\"fixed-case\">RBD<\/jats:styled-content>). Clinical neurological examination found no parkinsonian syndrome, no dysautonomic sign and no neurological focal sign. Dopamine transporter imaging [123I\u2010<jats:styled-content style=\"fixed-case\">FP<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">CIT<\/jats:styled-content> single photon emission computed tomography (<jats:styled-content style=\"fixed-case\">SPECT<\/jats:styled-content>)] did not find any presynaptic dopaminergic pathways degeneration. Brain magnetic resonance imaging showed a vascular lesion suggestive of cavernoma located in the pons. The present case illustrates the complexity of sleep disturbance diagnosis with a possible entanglement of aetiologies responsible for nocturnal agitation, and confirms that an isolated pons cavernoma should be considered among the rare causes of <jats:styled-content style=\"fixed-case\">RBD<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/jsr.12364","type":"journal-article","created":{"date-parts":[[2016,1,19]],"date-time":"2016-01-19T03:24:47Z","timestamp":1453173887000},"page":"211-215","source":"Crossref","is-referenced-by-count":11,"title":["Rapid eye movement sleep behaviour disorder symptomatic of a brain stem cavernoma"],"prefix":"10.1111","volume":"25","author":[{"given":"Sandra","family":"Felix","sequence":"first","affiliation":[{"name":"Unit\u00e9 d'hypnologie Service de Neurologie fonctionnelle et d'\u00e9pileptologie Hospices civils de Lyon H\u00f4pital Neurologique Bron France"},{"name":"Universit\u00e9 Claude Bernard Lyon 1 Lyon France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephane","family":"Thobois","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Claude Bernard Lyon 1 Lyon France"},{"name":"Service de Neurologie C Hospices civils de Lyon H\u00f4pital Neurologique Bron France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laure","family":"Peter\u2010Derex","sequence":"additional","affiliation":[{"name":"Unit\u00e9 d'hypnologie Service de Neurologie fonctionnelle et d'\u00e9pileptologie Hospices civils de Lyon H\u00f4pital Neurologique Bron France"},{"name":"Universit\u00e9 Claude Bernard Lyon 1 Lyon France"},{"name":"Service de Neurologie\u2010Sommeil Hospices civils de Lyon Centre Hospitalier Lyon Sud Pierre\u2010Benite France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,1,18]]},"reference":[{"key":"e_1_2_4_2_1","volume-title":"The International Classification of Sleep Disorders: Diagnostic and Coding Manual","author":"American Academy of Sleep Medicine (AASM)","year":"2005"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awm056"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.epirev.a036151"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/1352458506074644"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0004-282X2008000300012"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2008.03.005"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(11)70152-1"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(13)70056-5"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.52.8786"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.5665\/sleep.2874"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.55.6.894"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2008.12.006"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature04767"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(13)70078-4"},{"key":"e_1_2_4_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2006.099515"},{"key":"e_1_2_4_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2011.05.002"},{"key":"e_1_2_4_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1389-9457(02)00042-4"},{"key":"e_1_2_4_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20027"},{"key":"e_1_2_4_20_1","doi-asserted-by":"crossref","first-page":"211","DOI":"10.5664\/jcsm.28111","article-title":"Isolated cataplexy and REM sleep behavior disorder after pontine stroke","volume":"7","author":"Reynolds T. 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