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Autobiographical memory overgenerality, a behaviour characterized by difficulty recalling specific memories from one's own life, is recognized as a marker of depression. Previous studies have demonstrated the predictive quality of specific autobiographical memory recall on the course of depression in patients with obstructive sleep apnea. However, it remains unclear whether impaired autobiographical memory is simply a feature of depression, or whether it is also impaired in patients with obstructive sleep apnea without depression. This study aimed to investigate whether autobiographical memory impairments can be observed in patients with obstructive sleep apnea, independent of the severity of depressive symptoms. Twenty\u2010one patients with obstructive sleep apnea symptomatic for depressive symptoms (mean age\u00a0=\u00a043.43\u00a0years, <jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>\u00a0=\u00a09.97), 17 patients with obstructive sleep apnea asymptomatic for depressive symptoms (mean age\u00a0=\u00a040.65\u00a0years, <jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>\u00a0=\u00a09.39), and 20 healthy controls without sleep\u2010disordered breathing (mean age\u00a0=\u00a032.80\u00a0years, <jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>\u00a0=\u00a06.69) completed an Autobiographical Memory Test. Patients with obstructive sleep apnea symptomatic for depressive symptoms recalled significantly fewer specific memories when compared with healthy controls (<jats:italic>P\u00a0=\u00a0<\/jats:italic>0.010). No difference in the recall of specific autobiographical memory was observed between symptomatic and asymptomatic patients with obstructive sleep apnea. With regard to valence, symptomatic patients with obstructive sleep apnea recalled significantly fewer negative specific memories when compared with controls (<jats:italic>P\u00a0=\u00a0<\/jats:italic>0.010). Impairment in specific autobiographical memory recall can be observed in patients with obstructive sleep apnea, regardless of the severity of depressive symptoms; however, this effect may not be as prominent in younger patients with obstructive sleep apnea.<\/jats:p>","DOI":"10.1111\/jsr.12418","type":"journal-article","created":{"date-parts":[[2016,5,18]],"date-time":"2016-05-18T13:29:49Z","timestamp":1463578189000},"page":"605-611","source":"Crossref","is-referenced-by-count":5,"title":["Autobiographical memory impairment in obstructive sleep apnea patients with and without depressive symptoms"],"prefix":"10.1111","volume":"25","author":[{"given":"V Vien","family":"Lee","sequence":"first","affiliation":[{"name":"School of Health and Biomedical Sciences RMIT University Victoria Australia"},{"name":"Institute for Breathing and Sleep Austin Health Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Trinder","sequence":"additional","affiliation":[{"name":"Melbourne School of Psychological Sciences The University of Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melinda L.","family":"Jackson","sequence":"additional","affiliation":[{"name":"School of Health and Biomedical Sciences RMIT University Victoria Australia"},{"name":"Institute for Breathing and Sleep Austin Health Victoria Australia"},{"name":"Melbourne School of Psychological Sciences The University of Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,5,18]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"1","article-title":"Recollective qualities modulate hippocampal activation during autobiographical memory retrieval","author":"Addis D. 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