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We analysed 1412 participants from the Multi\u2010Ethnic Study of Atherosclerosis who underwent both overnight polysomnography and cardiac magnetic resonance imaging. Subjects had been recruited 10\u00a0years earlier when free of cardiovascular disease. Our main exposure is the presence of central sleep apnea as defined by central apnea\u2013hypopnea index\u00a0=\u00a05 or the presence of Cheyne\u2013Stokes breathing. Outcome variables were left ventricular mass\/height, left ventricular ejection fraction, and left ventricular mass\/volume ratio. Multivariate linear regression models adjusted for age, gender, race, waist circumference, tobacco use, hypertension, and the obstructive apnea\u2013hypopnea index were fit for the outcomes. Of the 1412 participants, 27 (2%) individuals had central sleep apnea. After adjusting for covariates, the presence of central sleep apnea was significantly associated with elevated left ventricular mass\/volume ratio (<jats:italic>\u03b2\u00a0<\/jats:italic>=\u00a00.11\u00a0\u00b1\u00a00.04\u00a0g\u00a0mL<jats:sup>\u22121<\/jats:sup>, <jats:italic>P\u00a0<\/jats:italic>=\u00a00.0071), an adverse cardiac finding signifying concentric remodelling.<\/jats:p>","DOI":"10.1111\/jsr.12501","type":"journal-article","created":{"date-parts":[[2017,2,21]],"date-time":"2017-02-21T17:09:17Z","timestamp":1487696957000},"page":"477-480","source":"Crossref","is-referenced-by-count":17,"title":["Association between central sleep apnea and left ventricular structure: the Multi\u2010Ethnic Study of Atherosclerosis"],"prefix":"10.1111","volume":"26","author":[{"given":"Sogol","family":"Javaheri","sequence":"first","affiliation":[{"name":"Brigham and Women's Hospital Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ravi K.","family":"Sharma","sequence":"additional","affiliation":[{"name":"Beth Israel Deaconess Medical Center Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Bluemke","sequence":"additional","affiliation":[{"name":"Radiology and Imaging Sciences NIH Clinical Center Bethesda MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Redline","sequence":"additional","affiliation":[{"name":"Brigham and Women's Hospital Boston MA USA"},{"name":"Beth Israel Deaconess Medical Center Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,2,21]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwf113"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.09.014"},{"key":"e_1_2_10_4_1","first-page":"877","article-title":"Racial\/ethnic differences in sleep disturbances: the Multi\u2010Ethnic Study of Atherosclerosis (MESA)","volume":"38","author":"Chen X.","year":"2014","journal-title":"Sleep"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/eht133"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.5665\/sleep.5962"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.5665\/sleep.5518"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201503-0536OC"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2013.05.061"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehu522"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2012.09.101"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00392-014-0774-3"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.114.000975"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.152.6.8520761"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.216.2.r00au14597"}],"container-title":["Journal of Sleep Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjsr.12501","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jsr.12501","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T12:47:53Z","timestamp":1696164473000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jsr.12501"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2,21]]},"references-count":14,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,8]]}},"alternative-id":["10.1111\/jsr.12501"],"URL":"https:\/\/doi.org\/10.1111\/jsr.12501","archive":["Portico"],"relation":{},"ISSN":["0962-1105","1365-2869"],"issn-type":[{"value":"0962-1105","type":"print"},{"value":"1365-2869","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,2,21]]}}}