{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T18:40:38Z","timestamp":1787164838442,"version":"build-2736575974"},"reference-count":36,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2017,11,24]],"date-time":"2017-11-24T00:00:00Z","timestamp":1511481600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Sleep Research"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>Previous studies have estimated an overall prevalence for narcolepsy between 15 and 70 cases per 100\u00a0000 inhabitants. We aimed to estimate the prevalence of narcolepsy in Catalunya (Catalonia), a north\u2010east region of Spain (7\u00a0424\u00a0754 inhabitants), on 31 December 2014 by identifying all living subjects diagnosed with narcolepsy. First, we identified patients diagnosed by one of the 13 sleep, paediatric or neurological departments that perform tests regularly to diagnose narcolepsy. In a second phase, we searched for additional patients with narcolepsy in a clinical database of the primary health\u2010care system. Clinical files were reviewed and narcolepsy diagnosis validated according to the Brighton Collaboration case definitions. Three hundred and twenty\u2010five patients had a validated diagnosis of narcolepsy in the specialized centres (mean age: 44.6\u00a0years, range: 6\u201389; male: 60.3%; 85% with narcolepsy type 1), including 17.8% cases in Brighton, definition level 1, 62.5% in level 2, 15.4% in level 3 and 4.3% in level 4a. The overall prevalence for narcolepsy was 4.4; 3.7 for narcolepsy type 1 and 0.7 cases per 100\u00a0000 inhabitants for narcolepsy type 2. Fifty\u2010six additional narcoleptic patients were identified in the primary health\u2010care system, increasing the overall prevalence to 5.2 cases per 100\u00a0000 inhabitants. Prevalence rates for narcolepsy type 1 increased from childhood to adulthood, but in subjects aged more than 50\u00a0years there was a substantial drop in prevalence rates, suggesting the presence of a significant pool of undiagnosed cases in this population. Narcolepsy can be considered a rare neurological disorder in Catalunya.<\/jats:p>","DOI":"10.1111\/jsr.12640","type":"journal-article","created":{"date-parts":[[2017,11,24]],"date-time":"2017-11-24T01:08:51Z","timestamp":1511485731000},"source":"Crossref","is-referenced-by-count":20,"title":["The prevalence of narcolepsy in Catalunya (Spain)"],"prefix":"10.1111","volume":"27","author":[{"given":"Ester","family":"Ti\u00f3","sequence":"first","affiliation":[{"name":"Neurology Department Althaia Xarxa Assistencial Universit\u00e0ria Manresa Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7113-8125","authenticated-orcid":false,"given":"Carles","family":"Gaig","sequence":"additional","affiliation":[{"name":"Multidisciplinary Sleep Unit Neurology Department Hospital Cl\u00ednic Barcelona Barcelona Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Neurodegenerativas (CIBERNED) Madrid 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