{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:22:52Z","timestamp":1790641372149,"version":"4.1.0"},"reference-count":40,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T00:00:00Z","timestamp":1519862400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["RO1MH079188"],"award-info":[{"award-number":["RO1MH079188"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["R01MH60413"],"award-info":[{"award-number":["R01MH60413"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000156","name":"Fonds de Recherche du Qu\u00e9bec - Sant\u00e9","doi-asserted-by":"publisher","award":["32207"],"award-info":[{"award-number":["32207"]}],"id":[{"id":"10.13039\/501100000156","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Sleep Research"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Two phenotypes have been proposed: insomnia with objective near\u2010normal sleep duration, related to increased psychological symptoms, and insomnia with objective short sleep duration, associated with cardiometabolic morbidity. Reduced heart rate variability has also been implicated in the pathophysiology of cardiometabolic disease; however, there are little data on whether cardiovascular function differs between patients with objective short sleep duration and near\u2010normal sleep duration. Participants (<jats:italic>M<\/jats:italic><jats:sub>age<\/jats:sub>\u00a0=\u00a049.9\u00a0\u00b1\u00a011.3\u00a0years; 62.8% female) were 180 adults with chronic insomnia (<jats:italic>M<\/jats:italic><jats:sub>duration<\/jats:sub>\u00a0=\u00a015.7\u00a0\u00b1\u00a013.6). Objective sleep duration was based on total sleep time averaged across two consecutive nights of polysomnography and subjective sleep duration was based on 2\u2010week sleep diaries. The sample was divided into two groups, with sleep duration shorter (polysomnography\u2010total sleep time: <jats:italic>n<\/jats:italic>\u00a0=\u00a046; sleep diary: <jats:italic>n<\/jats:italic>\u00a0=\u00a095) or equal\/longer (polysomnography\u2010total sleep time: <jats:italic>n<\/jats:italic>\u00a0=\u00a0134; sleep diary: <jats:italic>n<\/jats:italic>\u00a0=\u00a085) than 6\u00a0hr. Electrocardiogram data derived from polysomnography were used to obtain heart rate and heart rate variability during stage 2 (N2) and rapid eye movement sleep. Heart rate variability measures included absolute and normalized high\u2010frequency component, an index of parasympathetic activation, and the ratio of low\u2010 to high\u2010frequency (<jats:styled-content style=\"fixed-case\">LF<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">HF<\/jats:styled-content> ratio), an index of sympathovagal balance. After controlling for covariates (e.g., co\u2010morbidity), patients with objective short sleep duration had reduced high\u2010frequency (<jats:italic>p\u00a0<\/jats:italic>&lt;\u00a0.05) and elevated low\u2010frequency\/high\u2010frequency ratio (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.036) and heart rate (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.051) compared with patients with near\u2010normal sleep duration. No differences were observed between phenotypes when subjective sleep duration was used. Insomnia patients with objective short sleep duration showed significantly dampened parasympathetic activation and increased sympathovagal imbalance relative to their counterparts with near\u2010normal sleep duration. These findings highlight the importance of treating insomnia, as treatment may reduce the risk of cardiovascular disease.<\/jats:p>","DOI":"10.1111\/jsr.12663","type":"journal-article","created":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T05:22:56Z","timestamp":1519881776000},"source":"Crossref","is-referenced-by-count":91,"title":["Cardiovascular autonomic dysfunction in insomnia patients with objective short sleep duration"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9422-3472","authenticated-orcid":false,"given":"Denise C.","family":"Jarrin","sequence":"first","affiliation":[{"name":"\u00c9cole de psychologie Universit\u00e9 Laval Qu\u00e9bec QC Canada"},{"name":"Centre d\u2019\u00e9tude des troubles du sommeil Institut universitaire en sant\u00e9 mentale de Qu\u00e9bec Qu\u00e9bec QC Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans","family":"Ivers","sequence":"additional","affiliation":[{"name":"\u00c9cole de psychologie Universit\u00e9 Laval Qu\u00e9bec QC Canada"},{"name":"Centre d\u2019\u00e9tude des troubles du sommeil Institut universitaire en sant\u00e9 mentale de Qu\u00e9bec Qu\u00e9bec QC Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manon","family":"Lamy","sequence":"additional","affiliation":[{"name":"\u00c9cole de psychologie Universit\u00e9 Laval Qu\u00e9bec QC Canada"},{"name":"Centre d\u2019\u00e9tude des troubles du sommeil Institut universitaire en sant\u00e9 mentale de Qu\u00e9bec Qu\u00e9bec QC Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivy Y.","family":"Chen","sequence":"additional","affiliation":[{"name":"\u00c9cole de psychologie Universit\u00e9 Laval Qu\u00e9bec QC Canada"},{"name":"Centre d\u2019\u00e9tude des troubles du sommeil Institut universitaire en sant\u00e9 mentale de Qu\u00e9bec Qu\u00e9bec QC Canada"},{"name":"Department of Psychiatry and Human Behavior University of California, Irvine Orange CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison G.","family":"Harvey","sequence":"additional","affiliation":[{"name":"Department of Psychology University of California, Berkeley Berkeley CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles M.","family":"Morin","sequence":"additional","affiliation":[{"name":"\u00c9cole de psychologie Universit\u00e9 Laval Qu\u00e9bec QC Canada"},{"name":"Centre d\u2019\u00e9tude des troubles du sommeil Institut universitaire en sant\u00e9 mentale de Qu\u00e9bec Qu\u00e9bec QC Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,3]]},"reference":[{"key":"e_1_2_7_2_1","volume-title":"International classification of sleep disorders: Diagnostic and coding manual","author":"American Academy of Sleep Medicine","year":"2005"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"issue":"1","key":"e_1_2_7_4_1","first-page":"1","article-title":"Insomnia patients with objective short sleep duration have a blunted response to cognitive behavioral therapy for insomnia","volume":"40","author":"Bathgate C. 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