{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T18:38:09Z","timestamp":1769107089725,"version":"3.49.0"},"reference-count":31,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2018,4,6]],"date-time":"2018-04-06T00:00:00Z","timestamp":1522972800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Sleep Research"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>As sleep disturbances have been reported in spinocerebellar ataxias (SCAs), including types SCA1, SCA2, SCA3, SCA6 and SCA13, identification and management of these disturbances can help minimise their impact on SCA patients' overall body functions and quality of life. To our knowledge, there are no studies that investigate sleep disturbances in SCA10. Therefore, the aim of this study was to assess sleep disturbances in patients with SCA10. Twenty\u2010three SCA10 patients and 23 healthy controls were recruited. Patients were evaluated in terms of their demographic and clinical data, including disease severity (Scale for the Assessment and Rating of Ataxia, SARA) and excessive daytime sleepiness (Epworth Sleepiness Scale, ESS), and underwent polysomnography. SCA10 patients had longer rapid eye movement (REM) sleep (<jats:italic>p\u00a0<\/jats:italic>=\u00a0.04) and more REM arousals than controls (<jats:italic>p<\/jats:italic>&lt;\u00a0.0001). There was a correlation of REM sleep onset with the age of onset of symptoms (<jats:italic>r<\/jats:italic>\u00a0=\u00a0.459), and with disease duration (<jats:italic>r<\/jats:italic>\u00a0=\u00a0\u2212.4305). There also was correlation between the respiratory disturbance index (RDI) and SARA (<jats:italic>r<\/jats:italic>\u00a0=\u00a0\u2212.4013), and a strong indirect correlation between arousal index and age at onset of symptoms (<jats:italic>r<\/jats:italic>\u00a0=\u00a0\u2212.5756). In conclusion, SCA10 patients had sleep abnormalities that included more REM arousals and higher RDI than controls. Our SCA10 patients had sleep disorders related to shorter disease duration and lower severity of ataxia, in a pattern similar to that of other neurodegenerative diseases.<\/jats:p>","DOI":"10.1111\/jsr.12688","type":"journal-article","created":{"date-parts":[[2018,4,6]],"date-time":"2018-04-06T22:16:19Z","timestamp":1523052979000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Sleep disorders in spinocerebellar ataxia type 10"],"prefix":"10.1111","volume":"27","author":[{"given":"Ester","family":"London","sequence":"first","affiliation":[{"name":"Movement Disorders Unit Neurology Service Internal Medicine Department Hospital de Cl\u00ednicas Federal University of Paran\u00e1 Curitiba Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3533-0347","authenticated-orcid":false,"given":"Carlos H. F.","family":"Camargo","sequence":"additional","affiliation":[{"name":"Neurology Service, Hospital Universit\u00e1rio State University of Ponta Grossa Ponta Grossa Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandra","family":"Zanatta","sequence":"additional","affiliation":[{"name":"Polysomnography Unit Neurology Service, Hospital de Cl\u00ednicas Federal University of Paran\u00e1 Curitiba Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana C.","family":"Crippa","sequence":"additional","affiliation":[{"name":"Polysomnography Unit Neurology Service, Hospital de Cl\u00ednicas Federal University of Paran\u00e1 Curitiba Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salmo","family":"Raskin","sequence":"additional","affiliation":[{"name":"Group for Advanced Molecular Investigation Graduate Program in Health Sciences School of Medicine Pontif\u00edcia Universidade Cat\u00f3lica do Paran\u00e1 Curitiba Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renato P.","family":"Munhoz","sequence":"additional","affiliation":[{"name":"Movement Disorders Centre Toronto Western Hospital Toronto University Toronto ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsuo","family":"Ashizawa","sequence":"additional","affiliation":[{"name":"Neuroscience Research Program Methodist Hospital Research Institute Houston TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H\u00e9lio A. 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