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However, there is controversy surrounding this nomenclature. We will try to find the differences between different diagnoses of hypersomnia from the results of the long\u2010term follow\u2010up evaluation of a sleep study. We diagnosed teenagers who had developed excessive daytime sleepiness based on the criteria of the <jats:italic>International Classification of Sleep Disorders, 3rd edition<\/jats:italic>. Each individual received the same clinical neurophysiologic testing every year for 5\u00a0years after the initial diagnosis of narcolepsy type 1 (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>111) or type 2 (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>46). The follow\u2010up evaluation demonstrated that narcolepsy type 1 (narcolepsy\u2010cataplexy) is a well\u2010defined clinical entity, with very reproducible clinical neurophysiologic findings over time, whereas patients with narcolepsy type 2 presented clear clinical and test variability. By the fifth year of the follow\u2010up evaluation, 17.6% of subjects did not meet the diagnostic criteria of narcolepsy type 2, and 23.9% didn't show any two sleep\u2010onset rapid eye movement periods in multiple sleep latency during the 5\u2010year follow\u2010up. Therefore narcolepsy type 1 (narcolepsy\u2010cataplexy) is a well\u2010defined syndrome, with the presentation clearly related to the known consequences of destruction of hypocretin\/orexin neurons. Narcolepsy type 2 covers patients with clinical and test variability over time, thus bringing into question the usage of the term \u201cnarcolepsy\u201d to label these patients.<\/jats:p>","DOI":"10.1111\/jsr.12700","type":"journal-article","created":{"date-parts":[[2018,5,30]],"date-time":"2018-05-30T02:29:53Z","timestamp":1527647393000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Multiple sleep latency test in narcolepsy type 1 and narcolepsy type 2: A 5\u2010year follow\u2010up study"],"prefix":"10.1111","volume":"27","author":[{"given":"Yu\u2010Shu","family":"Huang","sequence":"first","affiliation":[{"name":"Department of Child Psychiatry Chang Gung Memorial Hospital and University College of Medicine Taoyuan Taiwan"},{"name":"Department of Psychiatry Chang Gung Memorial Hospital and Chang Gung University Taoyuan Taiwan"},{"name":"Craniofacial Research Center and Sleep Center Chang Gung Memorial Hospital Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Guilleminault","sequence":"additional","affiliation":[{"name":"Stanford University Sleep Medicine Division Redwood City CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheng\u2010Hui","family":"Lin","sequence":"additional","affiliation":[{"name":"Craniofacial Research Center and Sleep Center Chang Gung Memorial Hospital Taoyuan Taiwan"},{"name":"Department of Plastic and Reconstructive Surgery Chang Gung Memorial Hospital and Chang Gung University Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chia\u2010Hsiang","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Chang Gung Memorial Hospital and Chang Gung University Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0132-2170","authenticated-orcid":false,"given":"Wei\u2010Chih","family":"Chin","sequence":"additional","affiliation":[{"name":"Department of Child Psychiatry Chang Gung Memorial Hospital and University College of Medicine Taoyuan Taiwan"},{"name":"Department of Psychiatry Chang Gung Memorial Hospital and Chang Gung University Taoyuan Taiwan"},{"name":"Craniofacial Research Center and Sleep Center Chang Gung Memorial Hospital Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tzu\u2010Shuang","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Child Psychiatry Chang Gung Memorial Hospital and University College of Medicine Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,5,29]]},"reference":[{"key":"e_1_2_9_2_1","volume-title":"The International Classification of Sleep Disorders [ICSD] diagnostic and coding manual","author":"American Academy of Sleep Medicine","year":"2014"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2013.1589"},{"issue":"1","key":"e_1_2_9_4_1","first-page":"77","article-title":"Validation of a cataplexy questionnaire in 983 sleep\u2010disorders patients","volume":"22","author":"Anic\u2010Labat S.","year":"1999","journal-title":"Sleep"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/15.2.173"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2014.02.001"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2016.04.004"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/WNP.0000000000000192"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2015.06.007"},{"key":"e_1_2_9_10_1","first-page":"455","article-title":"The pediatric sleepiness scale (PDSS): Sleep habits and sleep outcome in middle\u2010school children","volume":"26","author":"Drake C.","year":"2003","journal-title":"Sleep"},{"key":"e_1_2_9_11_1","first-page":"1","volume-title":"Narcolepsy","author":"Guilleminault C.","year":"1975"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1974.00490400069008"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/4.1.23"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000005346"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2015.11.023"},{"key":"e_1_2_9_16_1","unstructured":"Iber C. Ancoli\u2010Israel S. Chesson A. L.Jr &Quan S. F..for the American Academy of Sleep Medicine(addended Berry RB Brooks R Gamaldo CE).The AASM manual for the scoring of sleep and associated events: rules terminology and technical specifications. 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