{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T11:20:51Z","timestamp":1769167251832,"version":"3.49.0"},"reference-count":30,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2018,9,28]],"date-time":"2018-09-28T00:00:00Z","timestamp":1538092800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01HL072067"],"award-info":[{"award-number":["R01HL072067"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Sleep Research"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We hypothesized that positive airway pressure treatment would induce nasal obstruction and decrease nasal cavity due to mucosal swelling. We further hypothesized that subjective and objective nasal obstruction at baseline would negatively affect positive airway pressure adherence. A total of 728 patients with sleep apnea were investigated in the Icelandic Sleep Apnea Cohort at baseline and 2\u2005years after starting positive airway pressure. Patients underwent home sleep apnea testing at baseline. Questionnaires were answered and acoustic rhinometry was completed at baseline and follow\u2010up. The proportion of patients reporting subjective nocturnal nasal obstruction was reduced (baseline: 35% versus follow\u2010up: 24%; <jats:italic>p\u00a0<\/jats:italic>&lt;\u00a00.001). Small interior nasal dimensions increased (<jats:italic>p\u2005<\/jats:italic>&lt;\u20050.001) independent of adherence to treatment. Small nasal volume at baseline was a determinant for becoming a non\u2010user of positive airway pressure treatment (odds ratio 2.22, confidence interval 95% 1.35\u20133.67, <jats:italic>p\u2005<\/jats:italic>=\u20050.002). Subjective nasal obstruction decreased 2\u2005years after initiating positive airway treatment in sleep apnea, and objectively small nasal dimensions increased. Small nasal volume at baseline was a negative predictor for positive airway pressure treatment adherence. Maybe most importantly, positive airway pressure treatment did not cause long\u2010term objective or subjective nasal obstruction.<\/jats:p>","DOI":"10.1111\/jsr.12768","type":"journal-article","created":{"date-parts":[[2018,9,28]],"date-time":"2018-09-28T07:30:15Z","timestamp":1538119815000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["PAP treatment in patients with OSA does not induce long\u2010term nasal obstruction"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8421-4804","authenticated-orcid":false,"given":"Maria","family":"V\u00e4rendh","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery Sk\u00e5ne University Hospital Lund Sweden"},{"name":"Faculty of Medicine Lund University Lund Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Morgan","family":"Andersson","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery Sk\u00e5ne University Hospital Lund Sweden"},{"name":"Faculty of Medicine Lund University Lund Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erla","family":"Bj\u00f6rnsd\u00f3ttir","sequence":"additional","affiliation":[{"name":"Sleep Department Landspitali \u2013 The National University Hospital of Iceland Reykjav\u00edk Iceland"},{"name":"Faculty of Medicine University of Iceland Reykjavik Iceland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erna S.","family":"Arnard\u00f3ttir","sequence":"additional","affiliation":[{"name":"Sleep Department Landspitali \u2013 The National University Hospital of Iceland Reykjav\u00edk Iceland"},{"name":"Faculty of Medicine University of Iceland Reykjavik Iceland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thorarinn","family":"Gislason","sequence":"additional","affiliation":[{"name":"Sleep Department Landspitali \u2013 The National University Hospital of Iceland Reykjav\u00edk Iceland"},{"name":"Faculty of Medicine University of Iceland Reykjavik Iceland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allan I.","family":"Pack","sequence":"additional","affiliation":[{"name":"Center for Sleep and Circadian Neurobiology University of Pennsylvania Philadelphia Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harald","family":"Hrubos\u2010Str\u00f8m","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Akershus University Hospital L\u00f8renskog Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arne","family":"Johannisson","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, Faculty of Medicine Lund University Lund Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sigurdur","family":"Juliusson","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery Landspitali \u2013 The National University Hospital of Iceland Reykjav\u00edk Iceland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,9,28]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-4486.2009.02042.x"},{"issue":"5","key":"e_1_2_9_3_1","first-page":"e002795.","article-title":"Nocturnal sweating \u2013 a common symptom of obstructive sleep apnoea: The Icelandic Sleep Apnoea Cohort","volume":"3","author":"Arnardottir E. 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