{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:35:33Z","timestamp":1753878933322,"version":"3.41.2"},"reference-count":40,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2018,12,18]],"date-time":"2018-12-18T00:00:00Z","timestamp":1545091200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["299901"],"award-info":[{"award-number":["299901"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Sleep Research"],"published-print":{"date-parts":[[2019,10]]},"abstract":"Summary<\/jats:title>The concordance of different indices from type\u20104 sleep studies in diagnosing and categorising the severity of obstructive sleep apnoea is not known. This is a critical gap as type\u20104 sleep studies are used to diagnose obstructive sleep apnoea<\/jats:styled-content> in some settings. Therefore, we aimed to determine the concordance between flow\u2010based apnoea\u2013hypopnoea index (AHI<\/jats:styled-content>flow50%<\/jats:sub>) and oxygen desaturation index (ODI<\/jats:styled-content>3%<\/jats:sub>) by measuring them concurrently. Using a random sub\u2010sample of 296 from a population\u2010based cohort who underwent two\u2010channel type\u20104 sleep studies, we assessed the concordance between AHI<\/jats:styled-content>flow50%<\/jats:sub> and ODI<\/jats:styled-content>3%<\/jats:sub>. We compared the prevalence of obstructive sleep apnoea<\/jats:styled-content> of various severities as identified by the two methods, and determined their concordance using coefficient Kappa(\u03ba). Participants were aged (mean\u2005\u00b1\u2005SD) 53\u2005\u00b1\u20050.9\u2005years (48% male). The body mass index was 28.8\u2005\u00b1\u20055.2\u2005kg\u2005m\u22122<\/jats:sup> and neck circumference was 37.4\u2005\u00b1\u20053.9\u2005cm. The median AHI<\/jats:styled-content>flow50%<\/jats:sub> was 5 (inter\u2010quartile range 2, 10) and median ODI<\/jats:styled-content>3%<\/jats:sub> was 9 (inter\u2010quartile range 4, 15). The obstructive sleep apnoea<\/jats:styled-content> prevalence reported using AHI<\/jats:styled-content>flow50%<\/jats:sub> was significantly lower than that reported using ODI<\/jats:styled-content>3%<\/jats:sub> at all severity thresholds. Although 90% of those with moderate\u2013severe obstructive sleep apnoea<\/jats:styled-content> classified using AHI<\/jats:styled-content>flow50%<\/jats:sub> were identified by using ODI<\/jats:styled-content>3%<\/jats:sub>, only 46% of those with moderate\u2013severe obstructive sleep apnoea<\/jats:styled-content> classified using ODI<\/jats:styled-content>3%<\/jats:sub> were identified by AHI<\/jats:styled-content>flow50%<\/jats:sub>. The overall concordance between AHI<\/jats:styled-content>flow50%<\/jats:sub> and ODI<\/jats:styled-content>3%<\/jats:sub> in diagnosing and classifying the severity of obstructive sleep apnoea<\/jats:styled-content> was only fair (\u03ba\u2005=\u20050.32), better for males (\u03ba\u2005=\u20050.42 [95% confidence interval 0.32\u20130.57] versus 0.22 [95% confidence interval 0.09\u20130.31]), and lowest for those with a body mass index\u00a0\u2265\u200535 (\u03ba\u2005=\u20050.11). In conclusion, ODI<\/jats:styled-content>3%<\/jats:sub> and AHI<\/jats:styled-content>flow50%<\/jats:sub> from type\u20104 sleep studies are at least moderately discordant. Until further evidence is available, the use of ODI<\/jats:styled-content>3%<\/jats:sub> as the measure of choice for type\u20104 sleep studies is recommended cautiously.<\/jats:p>","DOI":"10.1111\/jsr.12804","type":"journal-article","created":{"date-parts":[[2018,12,19]],"date-time":"2018-12-19T06:39:50Z","timestamp":1545201590000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Comparison of apnoea\u2013hypopnoea index and oxygen desaturation index when identifying obstructive sleep apnoea using type\u20104 sleep studies"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5879-6174","authenticated-orcid":false,"given":"Chamara V.","family":"Senaratna","sequence":"first","affiliation":[{"name":"Allergy & Lung Health Melbourne School of Population & Global Health The University of Melbourne Melbourne Australia"},{"name":"University of Sri Jayewardenepura Nugegoda Sri Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrian","family":"Lowe","sequence":"additional","affiliation":[{"name":"Allergy & Lung Health Melbourne School of Population & Global Health The University of Melbourne Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer L.","family":"Perret","sequence":"additional","affiliation":[{"name":"Allergy & Lung Health Melbourne School of Population & Global Health The University of Melbourne Melbourne Australia"},{"name":"Institute for Breathing and Sleep (IBAS) Heidelberg\/Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caroline","family":"Lodge","sequence":"additional","affiliation":[{"name":"Allergy & Lung Health Melbourne School of Population & Global Health The University of Melbourne Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gayan","family":"Bowatte","sequence":"additional","affiliation":[{"name":"Allergy & Lung Health Melbourne School of Population & Global Health The University of Melbourne Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael J.","family":"Abramson","sequence":"additional","affiliation":[{"name":"School of Public Health & Preventive Medicine Monash University Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruce R.","family":"Thompson","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Alfred Health Central Clinical School Monash University Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Garun","family":"Hamilton","sequence":"additional","affiliation":[{"name":"School of Clinical Sciences Monash University Clayton Australia"},{"name":"Department of Lung and Sleep Monash Health Clayton Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shyamali C.","family":"Dharmage","sequence":"additional","affiliation":[{"name":"Allergy & Lung Health Melbourne School of Population & Global Health The University of Melbourne Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,12,18]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"crossref","first-page":"263","DOI":"10.5664\/jcsm.27497","article-title":"Adult Obstructive Sleep Apnea Task Force of the American Academy of Sleep Medicine clinical guideline for the evaluation, management and long\u2010term care of obstructive sleep apnea in adults","volume":"5","author":"Adult Obstructive Sleep Apnea Task Force of the American Academy of Sleep Medicine","year":"2009","journal-title":"Journal of Clinical Sleep Medicine"},{"doi-asserted-by":"publisher","key":"e_1_2_8_3_1","DOI":"10.1093\/sleep\/22.5.667"},{"doi-asserted-by":"publisher","key":"e_1_2_8_4_1","DOI":"10.1164\/rccm.200810-1558OC"},{"doi-asserted-by":"publisher","key":"e_1_2_8_5_1","DOI":"10.1093\/sleep\/27.6.1171"},{"doi-asserted-by":"publisher","key":"e_1_2_8_6_1","DOI":"10.1016\/j.sleep.2004.08.005"},{"doi-asserted-by":"publisher","key":"e_1_2_8_7_1","DOI":"10.1016\/j.jsmc.2011.05.002"},{"volume-title":"The AASM manual for the scoring of sleep and associated events: Rules, terminology and technical specifications","year":"2012","author":"Berry R. B.","key":"e_1_2_8_8_1"},{"doi-asserted-by":"publisher","key":"e_1_2_8_9_1","DOI":"10.1016\/S0140-6736(08)61622-0"},{"doi-asserted-by":"publisher","key":"e_1_2_8_10_1","DOI":"10.7326\/M16-1301"},{"doi-asserted-by":"publisher","key":"e_1_2_8_11_1","DOI":"10.1001\/jama.2013.1823"},{"unstructured":"2014 Australasian Sleep Association Australia C. L. Chai-Coetzer J. Douglas D. McEvoy M. Naughton A. Neill P. Rochford G. Bhalla Guidelines for sleep studies in adults: Prepared for the Australasian Sleep Association 1 49","key":"e_1_2_8_12_1"},{"key":"e_1_2_8_13_1","doi-asserted-by":"crossref","first-page":"737","DOI":"10.5664\/jcsm.27032","article-title":"Clinical guidelines for the use of unattended portable monitors in the diagnosis of obstructive sleep apnea in adult patients. Portable Monitoring Task Force of the American Academy of Sleep Medicine","volume":"3","author":"Collop N. A.","year":"2007","journal-title":"Journal of Clinical Sleep Medicine"},{"key":"e_1_2_8_14_1","doi-asserted-by":"crossref","first-page":"531","DOI":"10.5664\/JCSM.1328","article-title":"Obstructive sleep apnea devices for Out\u2010Of\u2010Center (OOC) testing: Technology evaluation","volume":"7","author":"Collop N. A.","year":"2011","journal-title":"Journal of Clinical Sleep Medicine"},{"key":"e_1_2_8_15_1","first-page":"e007956","article-title":"Type III home sleep testing versus pulse oximetry: Is the respiratory disturbance index better than the oxygen desaturation index to predict the apnoea\u2010hypopnoea index measured during laboratory polysomnography?","volume":"5","author":"Dawson A.","year":"2015","journal-title":"British Medical Journal Open"},{"doi-asserted-by":"publisher","key":"e_1_2_8_16_1","DOI":"10.1016\/j.beem.2010.08.011"},{"key":"e_1_2_8_17_1","doi-asserted-by":"crossref","first-page":"387","DOI":"10.5664\/jcsm.26861","article-title":"Validation of the ApneaLink\u2122 for the screening of sleep apnea: A novel and simple single\u2010channel recording device","volume":"3","author":"Erman M. K.","year":"2007","journal-title":"Journal of Clinical Sleep Medicine"},{"doi-asserted-by":"publisher","key":"e_1_2_8_18_1","DOI":"10.1007\/s11325-016-1330-3"},{"doi-asserted-by":"publisher","key":"e_1_2_8_19_1","DOI":"10.1111\/jsr.12318"},{"doi-asserted-by":"publisher","key":"e_1_2_8_20_1","DOI":"10.1111\/j.1440-1843.2010.01797.x"},{"unstructured":"2007 American Academy of Sleep Medicine Westchester IL C. Iber S. A. Israel A. L. Chesson S. F. Quan For the American Academy of Sleep Medicine The AASM manual for the scoring of sleep and associated events: Rules terminology and technical specifications 57","key":"e_1_2_8_21_1"},{"doi-asserted-by":"publisher","key":"e_1_2_8_22_1","DOI":"10.3122\/jabfm.2015.04.140266"},{"doi-asserted-by":"publisher","key":"e_1_2_8_23_1","DOI":"10.1016\/j.wjorl.2015.08.001"},{"doi-asserted-by":"publisher","key":"e_1_2_8_24_1","DOI":"10.1016\/j.rmed.2011.04.003"},{"doi-asserted-by":"publisher","key":"e_1_2_8_25_1","DOI":"10.2307\/2529310"},{"doi-asserted-by":"publisher","key":"e_1_2_8_26_1","DOI":"10.1016\/j.smrv.2011.10.001"},{"doi-asserted-by":"publisher","key":"e_1_2_8_27_1","DOI":"10.1136\/thx.2007.088930"},{"doi-asserted-by":"publisher","key":"e_1_2_8_28_1","DOI":"10.5665\/sleep.1592"},{"key":"e_1_2_8_29_1","first-page":"1","volume-title":"Effectiveness of portable monitoring devices for diagnosing obstructive sleep apnea: Update of a systematic review","author":"Lux L.","year":"2004"},{"key":"e_1_2_8_30_1","first-page":"407","article-title":"Cohort profile: The Tasmanian Longitudinal Health STUDY (TAHS)","volume":"46","author":"Matheson M. C.","year":"2017","journal-title":"International Journal of Epidemiology"},{"doi-asserted-by":"publisher","key":"e_1_2_8_31_1","DOI":"10.1378\/chest.120.2.625"},{"doi-asserted-by":"publisher","key":"e_1_2_8_32_1","DOI":"10.1007\/s11325-010-0421-9"},{"doi-asserted-by":"publisher","key":"e_1_2_8_33_1","DOI":"10.1007\/s11325-011-0524-y"},{"doi-asserted-by":"publisher","key":"e_1_2_8_34_1","DOI":"10.1164\/rccm.200905-0773OC"},{"doi-asserted-by":"publisher","key":"e_1_2_8_35_1","DOI":"10.7326\/M12-3187"},{"doi-asserted-by":"publisher","key":"e_1_2_8_36_1","DOI":"10.1164\/ajrccm.161.2.9904031"},{"doi-asserted-by":"publisher","key":"e_1_2_8_37_1","DOI":"10.1161\/CIRCULATIONAHA.105.556746"},{"doi-asserted-by":"publisher","key":"e_1_2_8_38_1","DOI":"10.1016\/j.smrv.2016.07.002"},{"doi-asserted-by":"publisher","key":"e_1_2_8_39_1","DOI":"10.1111\/resp.12747"},{"doi-asserted-by":"publisher","key":"e_1_2_8_40_1","DOI":"10.1016\/j.smrv.2004.01.002"},{"volume-title":"Obesity: Preventing and managing the global epidemic","year":"2000","author":"World Health Organization","key":"e_1_2_8_41_1"}],"container-title":["Journal of Sleep Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjsr.12804","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jsr.12804","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jsr.12804","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jsr.12804","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T20:29:16Z","timestamp":1694291356000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jsr.12804"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12,18]]},"references-count":40,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["10.1111\/jsr.12804"],"URL":"https:\/\/doi.org\/10.1111\/jsr.12804","archive":["Portico"],"relation":{},"ISSN":["0962-1105","1365-2869"],"issn-type":[{"type":"print","value":"0962-1105"},{"type":"electronic","value":"1365-2869"}],"subject":[],"published":{"date-parts":[[2018,12,18]]},"assertion":[{"value":"2018-08-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-11-06","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-12-18","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e12804"}}