{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T18:58:45Z","timestamp":1785783525461,"version":"3.56.0"},"reference-count":38,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,1,24]],"date-time":"2019-01-24T00:00:00Z","timestamp":1548288000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100007543","name":"Grantov\u00e1 Agentura, Univerzita Karlova","doi-asserted-by":"publisher","award":["GA UK 64216"],"award-info":[{"award-number":["GA UK 64216"]}],"id":[{"id":"10.13039\/100007543","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003243","name":"Ministerstvo Zdravotnictv\u00ed Cesk\u00e9 Republiky","doi-asserted-by":"publisher","award":["16\u201028914A"],"award-info":[{"award-number":["16\u201028914A"]}],"id":[{"id":"10.13039\/501100003243","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Sleep Research"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:title>\n<jats:bold>Summary<\/jats:bold>\n<\/jats:title><jats:p>Fragmentary myoclonus is a result of muscle activity consisting of brief potentials in surface electromyography during polysomnography. Excessive fragmentary myoclonus is defined by increased intensity of the potentials. A few studies report <jats:styled-content style=\"fixed-case\">excessive fragmentary myoclonus<\/jats:styled-content> occurrence in neurodegenerative diseases. Because idiopathic rapid eye movement sleep behaviour disorder is considered as an early stage of neurodegeneration with involvement of the brainstem, we charted the prevalence and quantified the intensity of <jats:styled-content style=\"fixed-case\">excessive fragmentary myoclonus<\/jats:styled-content> in <jats:styled-content style=\"fixed-case\">idiopathic rapid eye movement sleep behaviour disorder<\/jats:styled-content>. Twenty\u2010nine patients (one woman, 28 men, mean age 68 years, <jats:italic>SD<\/jats:italic> 6.2) and 29 controls (two women, 27 men, mean age 65.6 years, <jats:italic>SD<\/jats:italic> 8.6) underwent <jats:styled-content style=\"fixed-case\">polysomnography<\/jats:styled-content>. Fragmentary myoclonus potentials were identified and counted according to internationally used criteria. Fragmentary myoclonus intensity was quantified by the fragmentary myoclonus index. E<jats:styled-content style=\"fixed-case\">xcessive fragmentary myoclonus<\/jats:styled-content> was diagnosed in 75.9% (22 subjects) in <jats:styled-content style=\"fixed-case\">idiopathic rapid eye movement sleep behaviour disorder<\/jats:styled-content>, while in 34.5% (10 subjects) among the controls (<jats:italic>p<\/jats:italic> = 0.003). Quantitative analysis showed a wide\u2010range <jats:styled-content style=\"fixed-case\">fragmentary myoclonus index<\/jats:styled-content> in <jats:styled-content style=\"fixed-case\">idiopathic rapid eye movement sleep behaviour disorder<\/jats:styled-content> (4.0\u2013632.4; median 60.7) and in the controls (0.8\u2013938.1; median 34.3). The overall difference in <jats:styled-content style=\"fixed-case\">fragmentary myoclonus index<\/jats:styled-content> was not significant between the groups; however, patients with <jats:styled-content style=\"fixed-case\">idiopathic rapid eye movement sleep behaviour disorder<\/jats:styled-content> showed trends for higher <jats:styled-content style=\"fixed-case\">fragmentary myoclonus index<\/jats:styled-content> scores in wakefulness (<jats:italic>p<\/jats:italic> = 0.027), N1 (<jats:italic>p<\/jats:italic> = 0.032), N3 (<jats:italic>p<\/jats:italic> = 0.046) and R (<jats:italic>p<\/jats:italic> = 0.007). F<jats:styled-content style=\"fixed-case\">ragmentary myoclonus index<\/jats:styled-content> does not correlate with age, <jats:styled-content style=\"fixed-case\">idiopathic rapid eye movement sleep behaviour disorder<\/jats:styled-content> duration or R stage atonia deficiency. The prevalence of <jats:styled-content style=\"fixed-case\">excessive fragmentary myoclonus<\/jats:styled-content> is higher in <jats:styled-content style=\"fixed-case\">idiopathic rapid eye movement sleep behaviour disorder<\/jats:styled-content> compared with the controls, so <jats:styled-content style=\"fixed-case\">fragmentary myoclonus<\/jats:styled-content> should be taken into account in future research of rapid eye movement sleep behaviour disorder and motor control in sleep.<\/jats:p>","DOI":"10.1111\/jsr.12819","type":"journal-article","created":{"date-parts":[[2019,1,24]],"date-time":"2019-01-24T22:13:44Z","timestamp":1548368024000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Fragmentary myoclonus in idiopathic rapid eye movement sleep behaviour 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