{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T03:18:10Z","timestamp":1784949490730,"version":"3.55.0"},"reference-count":15,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,6,18]],"date-time":"2020-06-18T00:00:00Z","timestamp":1592438400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Sleep Research"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Insufficient sleep syndrome (ISS) is prevalent, but poorly studied. This descriptive study was performed to determine its diagnostic challenges and clinical characteristics in a large (<jats:italic>n<\/jats:italic>\u00a0=\u00a03,461) retrospective sample from a single sleep laboratory. Based on actigraphy, polysomnography and multiple sleep latency tests, we diagnosed \u201csuspected insufficient sleep syndrome\u201d in patients with chronic sleepiness, short time in bed, longer sleep duration during weekends or vacation, and without evidence of other causes of sleepiness. For the diagnosis of \u201cdefinite insufficient sleep syndrome\u201d, we additionally required objectively confirmed resolution of sleepiness with actigraphy\u2010documented extension of time in bed. We diagnosed \u201csuspected insufficient sleep syndrome\u201d in 300 subjects. In 94 subjects, extension of sleep time with consecutive relief of sleepiness was attempted, but only 37 subjects succeeded, often despite being offered several attempts. \u201cDefinite insufficient sleep syndrome\u201d was confirmed in 36 patients. In these subjects, mean time in bed after sleep extension was above 8\u00a0hr per night and 84\u00a0min longer than at baseline. Narcolepsy\u2010like findings were frequently observed before sleep extension, but no sleep onset rapid eye movement sleep on polysomnography. This study indicates that fulfilling the diagnostic criteria of ISS is challenging in clinical practice. It further corroborates the importance of actigraphy and polysomnography for correct diagnosis.<\/jats:p>","DOI":"10.1111\/jsr.13109","type":"journal-article","created":{"date-parts":[[2020,6,19]],"date-time":"2020-06-19T00:20:23Z","timestamp":1592526023000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Extending sleep to confirm insufficient sleep syndrome is challenging"],"prefix":"10.1111","volume":"30","author":[{"given":"Heide","family":"Baumann\u2010Vogel","sequence":"first","affiliation":[{"name":"Department of Neurology University Hospital Zurich University of Zurich Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophia","family":"Hoff","sequence":"additional","affiliation":[{"name":"Department of Neurology University Hospital Zurich University of Zurich Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8435-1697","authenticated-orcid":false,"given":"Philipp O.","family":"Valko","sequence":"additional","affiliation":[{"name":"Department of Neurology University Hospital Zurich University of Zurich Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rositsa","family":"Poryazova","sequence":"additional","affiliation":[{"name":"Department of Neurology University Hospital Zurich University of Zurich Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther","family":"Werth","sequence":"additional","affiliation":[{"name":"Department of Neurology University Hospital Zurich University of Zurich Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3417-1978","authenticated-orcid":false,"given":"Christian R.","family":"Baumann","sequence":"additional","affiliation":[{"name":"Department of Neurology University Hospital Zurich University of Zurich Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,6,18]]},"reference":[{"key":"e_1_2_7_2_1","volume-title":"International classification of sleep disorders","author":"American Academy of Sleep Medicine (AASM)","year":"2014"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2013.1589"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/healthcare7010037"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awu391"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(18)30450-2"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2008.06.047"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/ped.13519"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2007.08.018"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.4368"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/28.1.113"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.25023"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2009.03.008"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.adolescence.2010.02.005"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/26.2.117"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1080\/15402002.2019.1578772"}],"container-title":["Journal of Sleep Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjsr.13109","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jsr.13109","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jsr.13109","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jsr.13109","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T21:31:17Z","timestamp":1693603877000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jsr.13109"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,18]]},"references-count":15,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["10.1111\/jsr.13109"],"URL":"https:\/\/doi.org\/10.1111\/jsr.13109","archive":["Portico"],"relation":{},"ISSN":["0962-1105","1365-2869"],"issn-type":[{"value":"0962-1105","type":"print"},{"value":"1365-2869","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,18]]},"assertion":[{"value":"2020-04-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-06-18","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e13109"}}