{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T07:32:31Z","timestamp":1774510351315,"version":"3.50.1"},"reference-count":40,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,8,27]],"date-time":"2020-08-27T00:00:00Z","timestamp":1598486400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Sleep Research"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This study examined the nature and characteristics of sleep\u2010disordered breathing, including obstructive sleep apnea and central sleep apnea, in patients with post\u2010stroke dysphagia, to determine the demographic, anthropometric and clinical variables that were associated with sleep\u2010disordered breathing. Thirty\u2010nine patients diagnosed with acute stroke (28 males and 11 females with a mean age of 72.3\u00a0\u00b1\u00a010.0\u00a0years) underwent overnight polysomnography (within 3.9\u00a0\u00b1\u00a01.6\u00a0days after admission). Sleep\u2010disordered breathing was described by the apnea\u2013hypopnea index and its obstructive and central components by the obstructive apnea\u2013hypopnea index and central apnea\u2013hypopnea index, respectively. Severity of dysphagia was assessed using the Mann Assessment of Swallowing Ability score. Severity of stroke and functional dependence were assessed by the National Institute of Health Stroke Scale and the modified Barthel index, respectively. Most of the cohort (87%) had moderate\u2010to\u2010severe dysphagia (Mann Assessment of Swallowing Ability of 143.2\u00a0\u00b1\u00a019.9). Sleep\u2010disordered breathing (apnea\u2010hypopnea index\u00a0\u2265\u00a05\u00a0events\/hr) was present in 38 participants (97%) with a mean apnea\u2013hypopnea index of 37.5\u00a0\u00b1\u00a024.4\u00a0events\/hr. Sleep\u2010disordered breathing was predominantly obstructive in nature, with a mean obstructive apnea\u2013hypopnea index and central apnea\u2013hypopnea index of 19.6\u00a0\u00b1\u00a015.7 and 11.4\u00a0\u00b1\u00a017.6\u00a0events\/hr, respectively. Multivariate linear regression analyses showed that the apnea\u2013hypopnea index was associated with sex (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.0001), body mass index (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.029) and the modified Barthel index (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.006); the obstructive apnea\u2013hypopnea index was associated with the Mann Assessment of Swallowing Ability (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.006), sex (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.004) and body mass index (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.015) and had a nonlinear relationship with the modified Barthel index (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.019); and the central apnea\u2013hypopnea index was associated with sex (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.027) and the modified Barthel index (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.019). The present study showed that dysphagia severity was associated with obstructive sleep apnea severity and this association was independent of sex, modified Barthel index and body mass index. However, stroke\u2010induced dysphagia was not associated with central sleep apnea or overall sleep\u2010disordered breathing.<\/jats:p>","DOI":"10.1111\/jsr.13179","type":"journal-article","created":{"date-parts":[[2020,8,28]],"date-time":"2020-08-28T14:39:07Z","timestamp":1598625547000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Sleep\u2010disordered breathing in patients with stroke\u2010induced dysphagia"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7109-0267","authenticated-orcid":false,"given":"Mohamed","family":"Estai","sequence":"first","affiliation":[{"name":"Centre for Sleep Science School of Human Sciences University of Western Australia Crawley WA Australia"},{"name":"The Australian e\u2010Health Research Centre CSIRO Perth WA 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