{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T18:11:11Z","timestamp":1785435071545,"version":"3.56.0"},"reference-count":15,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,9,29]],"date-time":"2020-09-29T00:00:00Z","timestamp":1601337600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Sleep Research"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Because of unspecific diagnostic criteria, there is much controversy around narcolepsy type 2, its existence and its frequency. With this retrospective and purely descriptive study, we aimed to compare the frequency of narcolepsy type 2 compared to the well\u2010described narcolepsy type 1, in a large (<jats:italic>n<\/jats:italic>\u00a0=\u00a03,782) retrospective sample from a single tertiary sleep centre. After 2\u00a0weeks washout of sleep\u2013wake active medication, all patients with excessive daytime sleepiness (<jats:italic>n<\/jats:italic>\u00a0=\u00a01,392) underwent 2\u00a0weeks actigraphy, polysomnography and multiple sleep latency test, and all diagnoses were made along current diagnostic criteria. Narcolepsy type 1 was diagnosed in 91 patients, and 191 patients without cataplexy had multiple sleep latency test (MSLT) results indicating narcolepsy. After exclusion of shift work syndrome (<jats:italic>n<\/jats:italic>\u00a0=\u00a019), suspected insufficient sleep syndrome (<jats:italic>n<\/jats:italic>\u00a0=\u00a0128), delayed sleep phase syndrome (<jats:italic>n<\/jats:italic>\u00a0=\u00a04) and obstructive sleep apnea (<jats:italic>n<\/jats:italic>\u00a0=\u00a034), six patients were diagnosed with narcolepsy type 2, of whom two patients later developed narcolepsy type 1. Altogether, our observations suggest that narcolepsy type 2 exists, but its frequency may be much lower compared to narcolepsy type 1. In addition, they emphasize the importance of scrupulously excluding other potential causes of sleepiness, if possible, with 2\u2010week actigraphy and polysomnography.<\/jats:p>","DOI":"10.1111\/jsr.13203","type":"journal-article","created":{"date-parts":[[2020,9,29]],"date-time":"2020-09-29T09:17:38Z","timestamp":1601371058000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Narcolepsy type 2: A rare, yet existing entity"],"prefix":"10.1111","volume":"30","author":[{"given":"Heide","family":"Baumann\u2010Vogel","sequence":"first","affiliation":[{"name":"Department of Neurology University Hospital Zurich University of Zurich Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lina","family":"Schreckenbauer","sequence":"additional","affiliation":[{"name":"Department of Neurology University Hospital Zurich University of Zurich Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8435-1697","authenticated-orcid":false,"given":"Philipp O.","family":"Valko","sequence":"additional","affiliation":[{"name":"Department of Neurology University Hospital Zurich University of Zurich Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther","family":"Werth","sequence":"additional","affiliation":[{"name":"Department of Neurology University Hospital Zurich University of Zurich Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3417-1978","authenticated-orcid":false,"given":"Christian R.","family":"Baumann","sequence":"additional","affiliation":[{"name":"Department of Neurology University Hospital Zurich University of Zurich Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,9,29]]},"reference":[{"key":"e_1_2_8_2_1","volume-title":"International classification of sleep disorders","author":"American Academy of Sleep Medicine (AASM)","year":"2014"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2013.1589"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41582-019-0226-9"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.5665\/sleep.3756"},{"key":"e_1_2_8_6_1","first-page":"e13109","article-title":"Extending sleep to confirm insufficient sleep syndrome is challenging","author":"Baumann\u2010Vogel H.","year":"2020","journal-title":"Journal of Sleep Research"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.5665\/sleep.3758"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/29.11.1429"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awu391"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2008.06.047"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2020.101306"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2009.03.008"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awl079"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.6882"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/29.7.890"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.2922"}],"container-title":["Journal of Sleep Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jsr.13203","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jsr.13203","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jsr.13203","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T21:31:45Z","timestamp":1693603905000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jsr.13203"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,29]]},"references-count":15,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["10.1111\/jsr.13203"],"URL":"https:\/\/doi.org\/10.1111\/jsr.13203","archive":["Portico"],"relation":{},"ISSN":["0962-1105","1365-2869"],"issn-type":[{"value":"0962-1105","type":"print"},{"value":"1365-2869","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,29]]},"assertion":[{"value":"2020-06-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-09-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-09-29","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e13203"}}