{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T12:56:50Z","timestamp":1789390610389,"version":"build-2803163510"},"reference-count":29,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,11,5]],"date-time":"2020-11-05T00:00:00Z","timestamp":1604534400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003554","name":"Lundbeckfonden","doi-asserted-by":"publisher","award":["R211\u20102015\u20102937"],"award-info":[{"award-number":["R211\u20102015\u20102937"]}],"id":[{"id":"10.13039\/501100003554","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009708","name":"Novo Nordisk Fonden","doi-asserted-by":"publisher","award":["NNF17OC0024718"],"award-info":[{"award-number":["NNF17OC0024718"]}],"id":[{"id":"10.13039\/501100009708","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Sleep Research"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Intracranial pressure (ICP) B\u2010waves are defined as short, repeating elevations of ICP of up to 50\u00a0mmHg with a frequency of 0.5\u20132 waves\/min. The presence of B\u2010waves in overnight recordings is regarded as a pathological phenomenon. However, the physiology of B\u2010waves is still not fully understood and studies with transcranial Doppler, as a surrogate marker for ICP, have suggested that B\u2010waves could be a normal physiological phenomenon. We present four patients without known structural neurological disease other than a coincidentally found unruptured intracranial aneurysm. One of the patients had experienced well\u2010controlled epilepsy for several years, but was included because ICP under these conditions is unlikely to be abnormal. Following informed consent, all four patients had a telemetric ICP probe implanted during a prophylactic operation with closure of the aneurysm. They underwent overnight ICP monitoring with simultaneous polysomnography (PSG) sleep studies at 8\u00a0weeks after the operation. These patients exhibited nocturnal B\u2010waves, but did not have major structural brain lesions. Their ICP values were within the normal range. Nocturnal B\u2010waves occurred in close association with sleep\u2010disordered breathing (SDB) in rapid eye movement (REM) and non\u2010REM sleep stages. SDB during REM sleep was associated with ramp\u2010type B\u2010waves; SDB during non\u2010REM sleep was associated with the sinusoidal type of B\u2010wave. We propose that B\u2010waves are a physiological phenomenon associated with SDB and that the mechanical changes during respiration could have an essential and previously unrecognised role in the generation of B\u2010waves.<\/jats:p>","DOI":"10.1111\/jsr.13214","type":"journal-article","created":{"date-parts":[[2020,11,6]],"date-time":"2020-11-06T07:20:18Z","timestamp":1604647218000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["B\u2010waves are present in patients without intracranial pressure disturbances"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9393-0092","authenticated-orcid":false,"given":"Casper Schwartz","family":"Riedel","sequence":"first","affiliation":[{"name":"Department of Neurosurgery Rigshospitalet Copenhagen Denmark"},{"name":"Danish Center for Sleep Medicine Department of Clinical Neurophysiology Rigshospitalet Glostrup Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4717-8597","authenticated-orcid":false,"given":"Isabel","family":"Martinez\u2010Tejada","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Rigshospitalet Copenhagen Denmark"},{"name":"Department of Health Technology Technical University of Denmark Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1896-7749","authenticated-orcid":false,"given":"Nicolas Hernandez","family":"Norager","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Rigshospitalet Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lykke","family":"Kempfner","sequence":"additional","affiliation":[{"name":"Danish Center for Sleep Medicine Department of Clinical Neurophysiology Rigshospitalet Glostrup Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6986-5254","authenticated-orcid":false,"given":"Poul","family":"Jennum","sequence":"additional","affiliation":[{"name":"Danish Center for Sleep Medicine Department of Clinical Neurophysiology Rigshospitalet Glostrup Denmark"},{"name":"Institute of Clinical Medicine University of Copenhagen Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2652-7495","authenticated-orcid":false,"given":"Marianne","family":"Juhler","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Rigshospitalet Copenhagen Denmark"},{"name":"Institute of Clinical Medicine University of Copenhagen Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,11,5]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.3171\/2014.2.JNS132209"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-70971-5_56"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199805000-00029"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.29.6.564"},{"issue":"7","key":"e_1_2_10_6_1","first-page":"603","article-title":"Middle cerebral artery blood flow velocity in healthy persons during wakefulness and sleep: A transcranial Doppler study","volume":"16","author":"Droste D. 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