{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T07:29:19Z","timestamp":1793172559747,"version":"4.5.0"},"reference-count":46,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,7,6]],"date-time":"2022-07-06T00:00:00Z","timestamp":1657065600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Sleep Research"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>This study aimed to evaluate the diagnostic accuracy of home sleep apnea testing using peripheral arterial tonometry for sleep apnea as an alternative to polysomnography. We conducted a systematic review and meta\u2010analysis of observational studies, randomized controlled trials, and diagnostic case\u2013control studies examining the diagnostic accuracy of peripheral arterial tonometry by searching the CENTRAL, MEDLINE, EMBASE, ICTRP and <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/clinicaltrials.gov\">ClinicalTrials.gov<\/jats:ext-link> databases on 5 October 2021. We assessed the risk of bias of the included studies using the Quality Assessment of Diagnostic Accuracy Studies\u20102 tool. A bivariate random\u2010effects model was generated to derive the summary point estimates of sensitivity and specificity with 95% confidence intervals at different apnea\u2013hypopnea index cutoffs. This meta\u2010analysis included 13 studies (1227 participants, median prevalence of sleep apnea with apnea\u2013hypopnea index \u2265\u20095 events per hr: 85%). The risk of bias in the included studies was low to moderate. The pooled sensitivity and specificity estimates were 96% (95% confidence interval: 93%\u201397%) and 44% (95% confidence interval: 32%\u201356%) at apnea\u2013hypopnea index \u2265\u20095 events per hr, 88% (85%\u201391%) and 74% (63%\u201383%) at apnea\u2013hypopnea index \u2267\u200515 events per hr, and 80% (66%\u201389%) and 90% (83%\u201395%) at apnea\u2013hypopnea index \u2267\u200530 events per hr, respectively. Peripheral arterial tonometry resulted in a significant number of false negatives and false positives at any apnea\u2013hypopnea index cutoff when applied to the median prevalence setting of the included studies. The inadequate sensitivity and specificity of peripheral arterial tonometry render it an unsuitable alternative to polysomnography for detecting sleep apnea for apnea\u2013hypopnea index \u2267\u20055, 15 and 30 events per hr.<\/jats:p>","DOI":"10.1111\/jsr.13682","type":"journal-article","created":{"date-parts":[[2022,7,7]],"date-time":"2022-07-07T01:05:31Z","timestamp":1657155931000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Diagnostic accuracy of home sleep apnea testing using peripheral arterial tonometry for sleep apnea: A systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6594-5342","authenticated-orcid":false,"given":"Masahiro","family":"Ichikawa","sequence":"first","affiliation":[{"name":"Department of Endocrinology and Diabetes Yokohama City University Medical Center  Yokohama 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