{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T11:07:58Z","timestamp":1784718478662,"version":"3.55.0"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,11,3]],"date-time":"2022-11-03T00:00:00Z","timestamp":1667433600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81870077"],"award-info":[{"award-number":["81870077"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82170098"],"award-info":[{"award-number":["82170098"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Sleep Research"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Sleep\u2010disordered breathing (SDB) is highly prevalent, but its rates of diagnosis and treatment are low. As a heterogeneous condition, it is associated with delayed diagnosis and\/or suboptimal treatment. We aimed to determine distinct SDB clusters and examine their association with medical care\u2010seeking behaviour and sleep habits in a community\u2010dwelling population in South China. Participants were enrolled in the \u2018Guangdong Sleep Health Study\u2019. Five distinct community sites were investigated. Participant information was collected, and overnight sleep monitoring was performed. Latent class analysis was performed to classify patients with SDB based on patterns of SDB\u2010related symptoms and signs. Overall, 1,524 patients with SDB were evaluated. Four distinct clusters were identified: \u2018minimally symptomatic\u2019 (Cluster 2), which was the most dominant subtype (41.6%), followed by \u2018pure insomnia\/fewer daytime symptoms\u2019 (Cluster 4; 24.7%), \u2018insomnia\/multiple daytime symptoms\u2019 (Cluster 3; 17.8%), and \u2018upper airway symptoms with sleepiness\u2019 (Cluster 1; 15.9%). The overall medical care\u2010seeking rate attributable to sleep and breathing disorders was only 3.3%: 10.3% in Cluster 3, 2.5% in Cluster 1, 2.1% in Cluster 4, and 1.3% in Cluster 2, in which Cluster 3 was the highest and Cluster 2 was the lowest (adjusted <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). Regarding the sleep habit of going to bed and waking up at a consistent time, Cluster 3 exhibited the worst performance and Cluster 2 the best. In conclusion, distinct phenotypic subtypes were identified in community\u2010dwelling patients with SDB. Tailored strategies to encourage medical care\u2010seeking, early identification, and optimisation of treatment are necessary considering the different subtypes.<\/jats:p>","DOI":"10.1111\/jsr.13762","type":"journal-article","created":{"date-parts":[[2022,11,3]],"date-time":"2022-11-03T08:10:27Z","timestamp":1667463027000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Distinct phenotypic clusters of sleep\u2010disordered breathing and their association with medical care\u2010seeking behaviour and sleep habits: the Guangdong Sleep Health Study"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0840-3600","authenticated-orcid":false,"given":"Longlong","family":"Wang","sequence":"first","affiliation":[{"name":"Sleep Center, Department of Pulmonary and Critical Care Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences Guangdong Provincial Geriatrics Institute  Guangzhou China"},{"name":"The Second School of Clinical Medicine Southern Medical University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8076-0338","authenticated-orcid":false,"given":"Qiong","family":"Ou","sequence":"additional","affiliation":[{"name":"Sleep Center, Department of Pulmonary and Critical Care Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences Guangdong Provincial Geriatrics Institute  Guangzhou China"},{"name":"The Second School of Clinical Medicine Southern Medical University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangliang","family":"Shan","sequence":"additional","affiliation":[{"name":"Department of Epidemiology &amp; Biostatistics, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences\/School of Basic Medicine Peking Union Medical College  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miaochan","family":"Lao","sequence":"additional","affiliation":[{"name":"Sleep Center, Department of Pulmonary and Critical Care Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences Guangdong Provincial Geriatrics Institute  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanxia","family":"Xu","sequence":"additional","affiliation":[{"name":"Sleep Center, Department of Pulmonary and Critical Care Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences Guangdong Provincial Geriatrics Institute  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guo","family":"Pei","sequence":"additional","affiliation":[{"name":"Sleep Center, Department of Pulmonary and Critical Care Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences Guangdong Provincial Geriatrics Institute  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,11,3]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/s1389-9457(00)00065-4"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(19)30198-5"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-1781(89)90047-4"},{"key":"e_1_2_10_5_1","first-page":"4","article-title":"China guidelines for type 2 diabetes prevention (2017 ed)","volume":"10","author":"Chinese Medical Association Diabetes Branch","year":"2018","journal-title":"Chinese Journal of Diabetes Mellitus"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0b013e31816d83e4"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.27497"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyy151"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/14.6.540"},{"key":"e_1_2_10_10_1","first-page":"15","article-title":"Guidelines for the prevention and treatment of dyslipidemia in Chinese adults (2016 revised edition)","volume":"16","author":"Joint Committee on the Revision of guidelines for the prevention and treatment of dyslipidemia in adults in China","year":"2017","journal-title":"Chinese General Practice"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/zsx214"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1001599"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.6994"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200805-717OC"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1989.00520460115022"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.18637\/jss.v042.i10"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201808-1509OC"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2015.09.005"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/zsx201"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph18179248"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.18630"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.119.13720"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0163439"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc07-1870"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/ehf2.13704"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325-017-1605-3"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325-022-02599-x"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00032314"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2019.09.002"}],"container-title":["Journal of Sleep Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jsr.13762","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jsr.13762","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jsr.13762","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T11:12:21Z","timestamp":1692443541000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jsr.13762"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,3]]},"references-count":28,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["10.1111\/jsr.13762"],"URL":"https:\/\/doi.org\/10.1111\/jsr.13762","archive":["Portico"],"relation":{},"ISSN":["0962-1105","1365-2869"],"issn-type":[{"value":"0962-1105","type":"print"},{"value":"1365-2869","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11,3]]},"assertion":[{"value":"2022-07-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-10-04","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-11-03","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e13762"}}