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This study aimed to determine the separate and combined associations of chronotype with obstructive sleep apnea and blood pressure in a middle\u2010aged community population. Adults (<jats:italic>n<\/jats:italic>\u00a0=\u2009811) from the Raine Study (female\u00a0=\u00a059.2%; age mean [range]\u00a0=\u00a056.6 [42.1\u201376.6] years) were assessed for chronotype (Morningness\u2013Eveningness Questionnaire), blood pressure and hypertension (doctor diagnosed or systolic blood pressure \u2265\u2009140\u2009mmHg and\/or diastolic \u2265\u200990\u2009mmHg), and obstructive sleep apnea at different in\u2010laboratory apnea\u2013hypopnea index thresholds (5, 10, 15\u2009events per hr). Linear and logistic regression models examined relationships between chronotype and the presence and severity of obstructive sleep apnea, blood pressure, hypertension, and blood pressure stratified by obstructive sleep apnea severity at above\u2010mentioned apnea\u2013hypopnea index thresholds. Covariates included age, sex, body mass index, alcohol consumption, smoking, physical activity, sleep duration, anti\u2010hypertensive medication, insomnia, and depressive symptoms. Most participants were categorised as morning (40%) or intermediate (43%), with 17% meeting criteria for evening chronotypes. Participants with apnea\u2013hypopnea index \u2265\u200915\u2009events per hr and morning chronotype had higher systolic (9.9\u2009mmHg, <jats:italic>p<\/jats:italic>\u00a0&lt;\u20090.001) and a trend for higher diastolic blood pressure (3.4\u2009mmHg, <jats:italic>p<\/jats:italic>\u00a0=\u20090.07) compared with those with an evening chronotype, and higher systolic blood pressure compared with those with an intermediate chronotype (4.8\u2009mmHg, <jats:italic>p<\/jats:italic>\u00a0=\u20090.03). Across chronotype categories, no differences in systolic or diastolic blood pressure or odds of hypertension were found at apnea\u2013hypopnea index thresholds of \u2265\u20095 or \u2265\u200910\u2009events per hr. Among participants with apnea\u2013hypopnea index \u2265\u200915\u2009events per hr, systolic blood pressure is higher in those with a morning chronotype than evening and intermediate chronotypes. Assessment for morning chronotype may improve risk stratification for hypertension in patients with obstructive sleep apnea.<\/jats:p>","DOI":"10.1111\/jsr.13778","type":"journal-article","created":{"date-parts":[[2022,11,4]],"date-time":"2022-11-04T08:54:11Z","timestamp":1667552051000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Cross\u2010sectional interrelationships between chronotype, obstructive sleep apnea and blood pressure in a middle\u2010aged community cohort"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1343-9552","authenticated-orcid":false,"given":"Kelly","family":"Sansom","sequence":"first","affiliation":[{"name":"Centre for Sleep Science, School of Human Sciences The University of Western Australia  Perth Western Australia Australia"},{"name":"West Australian Sleep Disorders Research Institute Queen Elizabeth II Medical Centre  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9534-8699","authenticated-orcid":false,"given":"Amy","family":"Reynolds","sequence":"additional","affiliation":[{"name":"Flinders Health and Medical Research Institute, College of Medicine and Public Health, Flinders University  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satvinder S.","family":"Dhaliwal","sequence":"additional","affiliation":[{"name":"Curtin Health Innovation Research Institute, Faculty of Health Sciences, Curtin University  Bentley Western Australia Australia"},{"name":"Singapore University of Social Sciences  Clementi Singapore"},{"name":"Duke\u2010NUS Medical School National University of Singapore  Queenstown Singapore"},{"name":"Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia  Gelugor Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3950-6079","authenticated-orcid":false,"given":"Jennifer","family":"Walsh","sequence":"additional","affiliation":[{"name":"Centre for Sleep Science, School of Human Sciences The University of Western Australia  Perth Western Australia Australia"},{"name":"West Australian Sleep Disorders Research Institute Queen Elizabeth II Medical Centre  Perth Western Australia Australia"},{"name":"Department of Pulmonary Physiology &amp; 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