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Our aim was to explore their impacts on functional outcomes at month 3 after stroke, and to assess the benefit of continuous positive airway pressure in patients with severe obstructive sleep apnea. Ninety patients with supra\u2010tentorial ischaemic stroke underwent clinical screening for sleep disorders and polysomnography at day 15\u2009\u00b1\u20094 after stroke in a multisite study. Patients with severe obstructive apnea (apnea\u2013hypopnea index \u2265\u200930 per hr) were randomized into two groups: continuous positive airway pressure\u2010treated and sham (1:1 ratio). Functional independence was assessed with the Barthel Index at month 3 after stroke in function of apnea\u2013hypopnea index severity and treatment group. Secondary objectives were disability (modified Rankin score) and National Institute of Health Stroke Scale according to apnea\u2013hypopnea index. Sixty\u2010one patients (71.8\u2009years, 42.6% men) completed the study: 51 (83.6%) had obstructive apnea (21.3% severe apnea), 10 (16.7%) daytime sleepiness, 13 (24.1%) insomnia, 3 (5.7%) depression, and 20 (34.5%) restless legs syndrome. Barthel Index, modified Rankin score and Stroke Scale were similar at baseline and 3\u2009months post\u2010stroke in the different obstructive sleep apnea groups. Changes at 3\u2009months in those three scores were similar in continuous positive airway pressure versus sham\u2010continuous positive airway pressure patients. In patients with worse clinical outcomes at month 3, mean nocturnal oxygen saturation was lower whereas there was no association with apnea\u2013hypopnea index. Poorer outcomes at 3\u2009months were also associated with insomnia, restless legs syndrome, depressive symptoms, and decreased total sleep time and rapid eye movement sleep.<\/jats:p>","DOI":"10.1111\/jsr.13964","type":"journal-article","created":{"date-parts":[[2023,6,20]],"date-time":"2023-06-20T10:43:53Z","timestamp":1687257833000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Functional recovery after ischemic stroke: Impact of different sleep health parameters"],"prefix":"10.1111","volume":"33","author":[{"given":"Claire","family":"Denis","sequence":"first","affiliation":[{"name":"Sleep\u2010Wake Disorders Unit, Department of Neurology Gui\u2010de\u2010Chauliac Hospital, CHU  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Jaussent","sequence":"additional","affiliation":[{"name":"INM University Montpellier, INSERM  Montpellier 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