{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:38:15Z","timestamp":1753879095251,"version":"3.41.2"},"reference-count":34,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,9,18]],"date-time":"2023-09-18T00:00:00Z","timestamp":1694995200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100007196","name":"Ministerie van Infrastructuur en Milieu","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007196","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Sleep Research"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Excessive daytime sleepiness is the core symptom of central disorders of hypersomnolence (CDH) and can directly impair driving performance. Sleepiness is reflected in relative alterations in distal and proximal skin temperature. Therefore, we examined the predictive value of skin temperature on driving performance. Distal and proximal skin temperature and their gradient (DPG) were continuously measured in 44 participants with narcolepsy type 1, narcolepsy type 2 or idiopathic hypersomnia during a standardised 1\u2010h driving test. Driving performance was defined as the standard deviation of lateral position (SDLP) per 5\u2009km segment (equivalent to 3\u2009min of driving). Distal and proximal skin temperature and DPG measurements were averaged over each segment and changes over segments were calculated. Mixed\u2010effect model analyses showed a strong, quadratic association between proximal skin temperature and SDLP (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and a linear association between DPG and SDLP (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.021). Proximal skin temperature changes over 3 to 15\u2009min were predictive for SDLP. Moreover, SDLP increased over time (0.34\u2009cm\/segment, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and was higher in men than in women (3.50\u2009cm, <jats:italic>p<\/jats:italic>\u2009=\u20090.012). We conclude that proximal skin temperature is a promising predictor for real\u2010time assessment of driving performance in people with CDH.<\/jats:p>","DOI":"10.1111\/jsr.14045","type":"journal-article","created":{"date-parts":[[2023,9,18]],"date-time":"2023-09-18T08:24:01Z","timestamp":1695025441000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Skin temperature as a predictor of on\u2010the\u2010road driving performance in people with central disorders of hypersomnolence"],"prefix":"10.1111","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0147-1624","authenticated-orcid":false,"given":"Veronique E. 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