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This study investigated whether variations in sleep schedules, particularly delayed sleep\u2013wake patterns, contribute to the diagnostic distinction between narcolepsy type 2 and idiopathic hypersomnia. The study included 871 patients aged 18\u201339\u2009years (316 with narcolepsy type 2, 555 with idiopathic hypersomnia). These patients were diagnosed based on MSLT results following polysomnography from November 2013 to November 2017. Patients' sleep habits, including bedtime and wake\u2010up times on weekdays and weekends during the 2\u2009weeks preceding the polysomnography\/Multiple Sleep Latency Test, were assessed using self\u2010reported sleep logs. A multivariate logistic regression analysis was conducted to identify factors associated with narcolepsy type 2 diagnosis. The analysis revealed that being male (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), younger age (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), shorter weekday sleep duration (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05), and a delayed weekday sleep midpoint time (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01) were significantly associated with a diagnosis of narcolepsy type 2. The study suggests that the conventionally fixed schedule of polysomnography and Multiple Sleep Latency Test administration may have contributed to the increased occurrence of sleep\u2010onset rapid eye movement periods particularly in individuals with a delayed sleep\u2013wake schedule.<\/jats:p>","DOI":"10.1111\/jsr.14402","type":"journal-article","created":{"date-parts":[[2024,11,13]],"date-time":"2024-11-13T12:19:52Z","timestamp":1731500392000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Sleep schedules and <scp>MSLT<\/scp>\u2010based diagnosis of narcolepsy type 2 and idiopathic hypersomnia: Exploring potential associations in a large clinical sample"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4538-5381","authenticated-orcid":false,"given":"Kentaro","family":"Matsui","sequence":"first","affiliation":[{"name":"Department of Clinical Laboratory, National Center 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