{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T05:59:25Z","timestamp":1790315965819,"version":"4.1.0"},"reference-count":13,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T00:00:00Z","timestamp":1752710400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T00:00:00Z","timestamp":1752710400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100003793","name":"Hj\u00e4rt-Lungfonden","doi-asserted-by":"publisher","award":["20190607"],"award-info":[{"award-number":["20190607"]}],"id":[{"id":"10.13039\/501100003793","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003793","name":"Hj\u00e4rt-Lungfonden","doi-asserted-by":"publisher","award":["20190611"],"award-info":[{"award-number":["20190611"]}],"id":[{"id":"10.13039\/501100003793","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Sleep Research"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Obstructive sleep apnea (OSA) has been hypothesised to promote cancer via intermittent hypoxia, and assessing what happens when OSA is\n                    <jats:italic>controlled<\/jats:italic>\n                    by continuous positive airway pressure (CPAP) may provide valuable insight. We conducted a meta\u2010analysis of three randomised controlled trials (SAVE, RICCADSA, ISAACC) assessing cancer incidence from adverse event data on neoplasms among OSA patients randomised to continuous positive airway pressure (CPAP) versus control. Across trials, cancer incidence was similar between groups, and meta\u2010analysis showed no statistically significant difference (CI 0.55\u20131.68). Treating sleep apnea with CPAP does not appear to markedly reduce the risk of incident cancers.\n                  <\/jats:p>","DOI":"10.1111\/jsr.70153","type":"journal-article","created":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T10:54:25Z","timestamp":1752749665000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["<scp>CPAP<\/scp>\n                    to Reduce the Risk of Cancer in\n                    <scp>OSA<\/scp>\n                    ?\u2014A Meta\u2010Analysis of 3\n                    <scp>RCTs<\/scp>"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2819-2799","authenticated-orcid":false,"given":"Jenny","family":"Theorell\u2010Hagl\u00f6w","sequence":"first","affiliation":[{"name":"Department of Medical Sciences, Respiratory, Allergy and Sleep Research Uppsala University  Uppsala 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Sleep (CIRUS), Woolcock Institute for Medical Research Macquarie University  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,17]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.15-0634"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00036.2018"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01935-2021"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.3600"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1606599"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201201-0130OC"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/zsae063"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201601-0088OC"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213\u20102600(25)00202\u20104"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2023.17465"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(19)30271-1"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325-025-03345-9"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsr.14089"}],"container-title":["Journal 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