{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T05:59:23Z","timestamp":1790315963617,"version":"4.1.0"},"reference-count":45,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:00:00Z","timestamp":1756339200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:00:00Z","timestamp":1756339200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Sleep Research"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Sleep\u2013wake disturbances and cognitive decline are among the most common nonmotor symptoms of Parkinson's disease (PD). Deep brain stimulation (DBS) can successfully alleviate motor symptoms. However, the impact on sleep\u2013wake disturbances and cognitive decline, and their interaction, is yet unclear. We aim to investigate changes in and interaction between subjective sleep and cognition following DBS. We performed a study on data from the Amsterdam\u2010PD\u2010DBS database with assessments at baseline and at 6\u2009months post\u2010operative. Subjective sleep was assessed with the sleep and sleepiness items of the Movement Disorder Society\u2010Unified Parkinson's Disease Rating Scale. Cognition was assessed with neuropsychological tests for the domains of language, processing speed, executive functioning, and memory. Three hundred and sixty\u2010five PD patients were included. Subjective sleep and sleepiness significantly improved after DBS. The proportion of patients with clinically relevant sleep disturbances dropped significantly from 76.4% to 50.1% (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001). Significant declines were observed in verbal fluency (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001,\n                    <jats:italic>p\u2009=<\/jats:italic>\n                    \u20090.005), processing speed (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001), and executive function (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001,\n                    <jats:italic>p\u2009=<\/jats:italic>\n                    \u20090.013), while delayed memory showed a significant improvement (\n                    <jats:italic>p\u2009=<\/jats:italic>\n                    \u20090.025). Significant associations were found for reduction in sleepiness and less decline in category fluency (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.014) while no significant relationship between changes in sleep and changes in cognitive outcomes was present. This study provides strong evidence for the beneficial effects of DBS on sleep and sleepiness. No evidence was found for an association between reduction in subjective sleep disturbances following DBS and change in cognition.\n                  <\/jats:p>","DOI":"10.1111\/jsr.70193","type":"journal-article","created":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:38:30Z","timestamp":1756427910000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The Effect of Deep Brain Stimulation on Sleep and Cognition in Patients With Parkinson's Disease"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-7039-6316","authenticated-orcid":false,"given":"Monique E. H.","family":"Valk\u2010Geuke","sequence":"first","affiliation":[{"name":"Department of Medical Psychology Amsterdam UMC  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gert J.","family":"Geurtsen","sequence":"additional","affiliation":[{"name":"Department of Medical Psychology Amsterdam UMC, Amsterdam Neuroscience  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5267-0784","authenticated-orcid":false,"given":"Rob M. A.","family":"de Bie","sequence":"additional","affiliation":[{"name":"Department of Neurology Amsterdam UMC, Amsterdam Neuroscience  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rick","family":"Schuurman","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Amsterdam UMC  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martijn","family":"Beudel","sequence":"additional","affiliation":[{"name":"Department of Neurology Amsterdam UMC, Amsterdam Neuroscience  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esm\u00e9e","family":"Verwijk","sequence":"additional","affiliation":[{"name":"Department of Medical Psychology Amsterdam UMC, Amsterdam Neuroscience  Amsterdam the Netherlands"},{"name":"Department of Psychology, Brain and Cognition University of Amsterdam  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,8,28]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2017.27"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsr.14453"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp\u20102020\u2010325546"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/ene.14108"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0190027"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2021.765203"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11065\u2010022\u201009540\u20109"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165\u20101781(89)90047\u20104"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/00207454.2019.1681423"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2016.08.001"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2019.00340"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.9708"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.25311"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474\u20104422(17)30299\u20105"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.22340"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.10639"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1212\/wnl.17.5.427"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2021.2979"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/806169"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/14.6.540"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.2174\/1570159X19666210215115718"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/npjparkd.2016.24"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2006.104.4.502"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11065\u2010020\u201009473\u20101"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13534\u2010022\u201000226\u2010y"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/34.5.601"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/mdc3.13471"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2022.867055"},{"key":"e_1_2_12_30_1","volume-title":"Trail Making Test: Manual for Administration and Scoring","author":"Reitan R. 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