{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T05:59:20Z","timestamp":1790315960529,"version":"4.1.0"},"reference-count":52,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T00:00:00Z","timestamp":1757980800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T00:00:00Z","timestamp":1757980800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","award":["ANR\u201021\u2010CE36\u20100001"],"award-info":[{"award-number":["ANR\u201021\u2010CE36\u20100001"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Sleep Research"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Sleep troubles and respiratory and allergic health issues are associated in children, but the timeline of their association is overlooked. This study investigates the associations between sleep patterns at age 1 and respiratory and allergic multi\u2010trajectories (RespA\u2010MTG) between ages 1 and 5.5, and the associations between these multi\u2010trajectories and sleep at age 5.5 in the ELFE birth cohort. Sleep clusters at ages 1 and 5.5 (based on nocturnal and diurnal sleep duration, sleep onset difficulties, and night awakenings) and RespA\u2010MTG between ages 1 and 5.5 (based on wheezing, asthma medication, eczema, allergic conjunctivitis) were identified using data\u2010driven methods. Associations between sleep clusters and RespA\u2010MTG were assessed using multinomial regressions adjusted for confounders in 9577 children. Two sleep clusters were identified at ages 1 and 5.5: good sleepers (79.9% at age 1, 83.1% at 5.5) and poor sleepers (20.1% and 16.9%, respectively). Four RespA\u2010MTG were identified: pauci\u2010symptomatic (44.4%), persistent non\u2010respiratory allergic symptoms (23.1%), transient early respiratory symptoms (25.2%), and persistent respiratory and allergic symptoms (7.3%). Poor sleep at age 1 was associated with higher odds of transient early respiratory symptoms (Odds Ratio [95% Confidence Interval], 1.14 [0.99\u20131.31]) and persistent respiratory and allergic symptoms (1.29 [1.05\u20131.59]). Results were reinforced in children without wheezing at 2\u2009months. A borderline association was observed between persistent respiratory and allergic symptoms and sleep at 5.5 in good sleepers at 1\u2009year (1.22 [0.98\u20131.50]). In conclusion, sleep disturbances at age 1 are associated with later poorer respiratory and allergic health, suggesting early sleep troubles may predict these health concerns.<\/jats:p>","DOI":"10.1111\/jsr.70208","type":"journal-article","created":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T05:05:02Z","timestamp":1758085502000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Sleep and Trajectories of Respiratory and Allergic Symptoms Between 1 and 5.5\u2009Years of Age in the Elfe Birth Cohort"],"prefix":"10.1111","volume":"35","author":[{"given":"Daniele","family":"Saade","sequence":"first","affiliation":[{"name":"Universit\u00e9 Paris Cit\u00e9 and Universit\u00e9 Sorbonne Paris Nord, Inserm, INRAE Center for Research in Epidemiology and StatisticS (CRESS)  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1524-8071","authenticated-orcid":false,"given":"Rosalie","family":"Delvert","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris\u2010Saclay, UVSQ, Univ. Paris\u2010Sud, Inserm, \u00c9quipe d'Epid\u00e9miologie Respiratoire int\u00e9grative CESP  Villejuif France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chantal","family":"Raherison\u2010Semjen","sequence":"additional","affiliation":[{"name":"Bordeaux University, Inserm, Bordeaux Population Health Research Center Team EPICENE, UMR 1219  Bordeaux France"},{"name":"Service de Pneumologie Centre Hospitalier Universitaire Pointe\u2010a\u2010Pitre Abymes  Pointe\u2010a\u2010Pitre Guadeloupe"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Orianne","family":"Dumas","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris\u2010Saclay, UVSQ, Univ. Paris\u2010Sud, Inserm, \u00c9quipe d'Epid\u00e9miologie Respiratoire int\u00e9grative CESP  Villejuif France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed","family":"Sedki","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris\u2010Saclay, UVSQ, Univ. Paris\u2010Sud, Inserm Oncostat, CESP, Inserm  Villejuif France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie\u2010No\u00eblle","family":"Dufourg","sequence":"additional","affiliation":[{"name":"Unit\u00e9 Mixte Inserm\u2010Ined\u2010EFS Elfe INED  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Blandine","family":"de Lauzon\u2010Guillain","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris Cit\u00e9 and Universit\u00e9 Sorbonne Paris Nord, Inserm, INRAE Center for Research in Epidemiology and StatisticS (CRESS)  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00e9n\u00e9dicte","family":"Leynaert","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris\u2010Saclay, UVSQ, Univ. Paris\u2010Sud, Inserm, \u00c9quipe d'Epid\u00e9miologie Respiratoire int\u00e9grative CESP  Villejuif France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Nadif","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris\u2010Saclay, UVSQ, Univ. Paris\u2010Sud, Inserm, \u00c9quipe d'Epid\u00e9miologie Respiratoire int\u00e9grative CESP  Villejuif France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annabelle","family":"B\u00e9dard","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris\u2010Saclay, UVSQ, Univ. 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