{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T06:16:46Z","timestamp":1779257806007,"version":"3.51.4"},"reference-count":29,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T00:00:00Z","timestamp":1765152000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T00:00:00Z","timestamp":1765152000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100016469","name":"Takeda Pharmaceuticals International","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016469","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100020595","name":"National Science and Technology Council","doi-asserted-by":"publisher","award":["# NSTC 112\u20102314\u2010B\u2010182A\u2010032\u2010MY3"],"award-info":[{"award-number":["# NSTC 112\u20102314\u2010B\u2010182A\u2010032\u2010MY3"]}],"id":[{"id":"10.13039\/100020595","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Sleep Research"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Central hypersomnia disorder (CHD) may result in a higher risk of injury\/accident. The present study aims to investigate the real\u2010world risk by tracing patients in a clinical cohort for 4\u2009years. We tracked the injury\/accident risk of CHD clinical cohort patients from Taiwan's National Health Insurance Research Database (NHIRD) and compared it with controls. Data were collected based on the International Classification of Diseases, Tenth Revision. Patients were categorised by diagnosis, gender and age, with each subgroup compared to age\u2010 and gender\u2010matched controls. Group differences were analysed using the Chi\u2010square test and\n                    <jats:italic>t<\/jats:italic>\n                    \u2010test. Bonferroni correction was used for post hoc analysis. A total of 386 CHD clinical cohort patients were included. Narcolepsy type 1 patients had the highest subjective and objective symptom severity (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001). Compared to controls, CHD patients had a significantly higher risk of injury and accident of up to 61.92% and 7.51% during the 4\u2010year follow\u2010up, necessitating clinical visits. Narcolepsy type 2 patients have the highest risk of injury (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.005). Age\/gender differences were found. Males had a higher specific\u2010site injury risk (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.045) than females, while females had a higher transportation accident risk than controls (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.048). Children\/adolescents had a higher risk in total injury and multiple\u2010site injury than controls (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.024,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.014), and adults had a higher risk in specific\u2010site injury and transportation accident (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.020,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.004). In conclusion, CHD patients had a higher risk of injury\/accident, even among those with milder symptoms. Gender and age differences in these risks were observed. Our findings highlight the importance of hypersomnia treatment and individualised considerations in clinical practice.\n                  <\/jats:p>","DOI":"10.1111\/jsr.70260","type":"journal-article","created":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T04:40:39Z","timestamp":1765255239000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Risks of Injury and Accident in Patients With Central Hypersomnia: A Cohort Study in Taiwan"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-1521-2317","authenticated-orcid":false,"given":"Tsun\u2010Yi","family":"Roan","sequence":"first","affiliation":[{"name":"Division of Psychiatry and Sleep Center Chang Gung Memorial Hospital  Taoyuan Taiwan"},{"name":"Department of Psychiatry Taipei City Psychiatric Center, Taipei City Hospital  Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu\u2010Shu","family":"Huang","sequence":"additional","affiliation":[{"name":"Division of Psychiatry and Sleep Center Chang Gung Memorial Hospital  Taoyuan Taiwan"},{"name":"College of Medicine, Chang Gung University  Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hsiao\u2010Ting","family":"Juang","sequence":"additional","affiliation":[{"name":"Department of Artificial Intelligence Chang Gung University  Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shu\u2010Chen","family":"Chang","sequence":"additional","affiliation":[{"name":"Research Services Center for Health Information, Chang Gung University  Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chee\u2010Jen","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Artificial Intelligence Chang Gung University  Taoyuan Taiwan"},{"name":"Research Services Center for Health Information, Chang Gung University  Taoyuan Taiwan"},{"name":"Division of Gynecologic Oncology, Department of Obstetrics and Gynecology Chang Gung Memorial Hospital at Linkou  Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei\u2010Chih","family":"Chin","sequence":"additional","affiliation":[{"name":"Division of Psychiatry and Sleep Center Chang Gung Memorial Hospital  Taoyuan Taiwan"},{"name":"College of Medicine, Chang Gung University  Taoyuan Taiwan"},{"name":"College of Life Sciences and Medicine, National Tsing Hua University  Hsinchu Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,12,8]]},"reference":[{"key":"e_1_2_13_2_1","volume-title":"International Classificationof Sleep Disorders, Third Edition, Text Revision (ICSD\u20103\u2010TR)","author":"American Academy of Sleep 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