{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T18:42:37Z","timestamp":1787510557450,"version":"build-2736575974"},"reference-count":115,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T00:00:00Z","timestamp":1770595200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T00:00:00Z","timestamp":1770595200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Sleep Research"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Sleep is fundamental for infant development and health, playing a critical role in cognitive, socio\u2010emotional, and physical growth. However, environmental factors can impact the quality and duration of sleep in infants. This review synthesises current evidence on the associations between environmental chemical exposures and infant sleep outcomes, with a focus on the first 1000\u2009days of life. Infants may be exposed to environmental pollutants before birth, through the placenta, or after birth, via breastfeeding, diet, and external sources such as inhalation, dust contact, or hand\u2010to\u2010mouth exposure. Given their ongoing development, foetuses and infants are particularly vulnerable to these pollutants. This period of rapid growth and maturation represents a highly sensitive window for environmental exposures. This review covers various categories of environmental pollutants, including persistent organic pollutants (PCBs, dioxins), non\u2010persistent pollutants (phthalates, BPA), air pollutants (particulate matter, second\u2010hand smoke), and water contaminants (nitrates, microplastics). Environmental chemicals exposure could be assessed using parental questionnaires or biological monitoring, while sleep is evaluated using actigraphy, polysomnography, or parental reporting. Some evidence suggests that both prenatal and postnatal exposure to environmental contaminants may be associated with sleep disturbances in children, particularly in girls. Despite the numerous studies on adults and the mechanisms associated with these pollutants (neurotoxicity, endocrine disruption), which suggest an effect on sleep, there is a lack of studies in children, resulting in limited associations in the literature. Therefore, it is imperative to conduct studies on environmental pollutants present in breast milk, diet, and\/or ambient air to understand their impact on infant sleep.<\/jats:p>","DOI":"10.1111\/jsr.70286","type":"journal-article","created":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T10:38:37Z","timestamp":1770633517000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Impact of Environmental Exposure on Infant Sleep : The Exposome Approach"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-5969-340X","authenticated-orcid":false,"given":"Zeina","family":"Halbouty","sequence":"first","affiliation":[{"name":"P\u00e9riTox Laboratory (UMR_I 01), UPJV\/INERIS, Jules Verne University of Picardy  Amiens France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debora","family":"Tuka","sequence":"additional","affiliation":[{"name":"P\u00e9riTox Laboratory (UMR_I 01), UPJV\/INERIS, Jules Verne University of Picardy  Amiens France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erwan","family":"Stephan\u2010Blanchard","sequence":"additional","affiliation":[{"name":"P\u00e9riTox Laboratory (UMR_I 01), UPJV\/INERIS, Jules Verne University of Picardy  Amiens France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronique","family":"Bach","sequence":"additional","affiliation":[{"name":"P\u00e9riTox Laboratory (UMR_I 01), UPJV\/INERIS, Jules Verne University of Picardy  Amiens France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Tourneux","sequence":"additional","affiliation":[{"name":"P\u00e9riTox Laboratory (UMR_I 01), UPJV\/INERIS, Jules Verne University of Picardy  Amiens France"},{"name":"Neonatal Intensive Care Unit, Amiens University Hospital  Amiens France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elodie","family":"Haraux","sequence":"additional","affiliation":[{"name":"P\u00e9riTox Laboratory (UMR_I 01), UPJV\/INERIS, Jules Verne University of Picardy  Amiens France"},{"name":"Paediatric Surgery Unit, Amiens University Hospital  Amiens France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Chardon","sequence":"additional","affiliation":[{"name":"P\u00e9riTox Laboratory (UMR_I 01), UPJV\/INERIS, Jules Verne University of Picardy  Amiens France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,2,9]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2015.02.536"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(22)02319\u20104"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.puhe.2018.02.007"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651\u20102227.1995.tb13679.x"},{"issue":"3","key":"e_1_2_9_6_1","first-page":"178","article-title":"Parental Environmental Tobacco Smoking and the Prevalence of Respiratory Diseases in Primary School Children","volume":"62","author":"Arghir O. C.","year":"2013","journal-title":"Pneumologia"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/zsw066"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/15287390701598234"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cppeds.2016.12.001"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2019.12.002"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.1204934"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2019.01.012"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOP.0b013e32835e1eb6"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.202204\u20100740OC"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijheh.2016.05.006"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1139\/apnm\u20102015\u20100627"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.3390\/medicina54040061"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ypmed.2019.02.028"},{"key":"e_1_2_9_19_1","first-page":"135","volume-title":"Handbook of Clinical Neurology","author":"Costa L. G.","year":"2015"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.7.7.859"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1289\/EHP8262"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0891\u20105245(03)00150\u20100"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/wcs.52"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12940\u2010021\u201000819\u20107"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.9030"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1038\/pr.2018.52"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2023.107856"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0370\u20104475(82)80024\u20105"},{"key":"e_1_2_9_29_1","unstructured":"FEES.2023.Projet FEES\u2014Femmes Enceintes Environnement et Sant\u00e9."},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2020.101276"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.fpc.0000189796.21770.d3"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ntt.2023.107152"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/782462"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0378\u20103782(02)00018\u2010X"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1517\/17425255.2012.699041"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325\u2010020\u201002206\u2010x"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474\u20104422(13)70278\u20103"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2021.725829"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11356\u2010020\u201010767\u20103"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acap.2019.03.008"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2018.01.016"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijheh.2007.07.011"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.00108387"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1021\/es052580b"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/desc.13456"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2023.108070"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.3390\/toxics12110795"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1289\/EHP5564"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0378\u20104347(01)00467\u20104"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24833"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2019.105010"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1159\/000508055"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00113113"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envres.2018.05.033"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1081\/cbi\u2010100106082"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2023.e14359"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.3109\/10408444.2013.860075"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.5799"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxlet.2007.11.001"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.2023.0048"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.1038\/s12276\u2010020\u20100394\u20100"},{"key":"e_1_2_9_62_1","doi-asserted-by":"publisher","DOI":"10.1097\/MED.0000000000000090"},{"key":"e_1_2_9_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2023.104609"},{"key":"e_1_2_9_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envres.2020.110406"},{"key":"e_1_2_9_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.infbeh.2022.101713"},{"key":"e_1_2_9_66_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox10040550"},{"key":"e_1_2_9_67_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/20.5.323"},{"key":"e_1_2_9_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2022.133948"},{"key":"e_1_2_9_69_1","doi-asserted-by":"publisher","DOI":"10.1053\/smrv.2002.0243"},{"key":"e_1_2_9_70_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24021455"},{"key":"e_1_2_9_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2010.05.020"},{"key":"e_1_2_9_72_1","unstructured":"Organisation Mondiale de la Sante.2019.Le Message de l'OMS au Jeune Enfant: Pour Grandir en Bonne Sant\u00e9 ne Pas Trop Rester Assis et Jouer Davantage."},{"key":"e_1_2_9_73_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.10336"},{"key":"e_1_2_9_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2023.107763"},{"key":"e_1_2_9_75_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.8b00299"},{"key":"e_1_2_9_76_1","doi-asserted-by":"publisher","DOI":"10.1289\/EHP11750"},{"key":"e_1_2_9_77_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102869.1993.tb00075.x"},{"key":"e_1_2_9_78_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12989\u2010020\u201000358\u2010y"},{"key":"e_1_2_9_79_1","doi-asserted-by":"publisher","DOI":"10.3390\/toxics13010062"},{"key":"e_1_2_9_80_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.00108s3511"},{"key":"e_1_2_9_81_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.152.3722.604"},{"key":"e_1_2_9_82_1","doi-asserted-by":"publisher","DOI":"10.1080\/87565641.2014.973498"},{"key":"e_1_2_9_83_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.24256"},{"key":"e_1_2_9_84_1","doi-asserted-by":"publisher","DOI":"10.1097\/EE9.0000000000000134"},{"key":"e_1_2_9_85_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2022.995503"},{"key":"e_1_2_9_86_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envres.2022.114219"},{"key":"e_1_2_9_87_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2018.11.381"},{"issue":"16","key":"e_1_2_9_88_1","first-page":"4","article-title":"The Neurotransmitters of Sleep","volume":"65","author":"Siegel J. M.","year":"2004","journal-title":"Journal of Clinical Psychiatry"},{"key":"e_1_2_9_89_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2021.132375"},{"key":"e_1_2_9_90_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00244\u2010007\u20109015\u20103"},{"key":"e_1_2_9_91_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41390\u2010020\u20101020\u20105"},{"key":"e_1_2_9_92_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2016.05.001"},{"key":"e_1_2_9_93_1","unstructured":"Stockholm.2001.Stockholm Convention on Persistent Organic Pollutants."},{"key":"e_1_2_9_94_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2012.03.001"},{"key":"e_1_2_9_95_1","doi-asserted-by":"publisher","DOI":"10.2147\/NSS.S125992"},{"key":"e_1_2_9_96_1","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.16\u20100214"},{"key":"e_1_2_9_97_1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2004.14.1012"},{"key":"e_1_2_9_98_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleepadvances\/zpae013"},{"key":"e_1_2_9_99_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325\u2010024\u201003210\u20101"},{"key":"e_1_2_9_100_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2014.01.004"},{"key":"e_1_2_9_101_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.10155"},{"key":"e_1_2_9_102_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0312127"},{"key":"e_1_2_9_103_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2023.101805"},{"key":"e_1_2_9_104_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2023.130959"},{"key":"e_1_2_9_105_1","volume-title":"Second\u2010Hand Smoke Impacts Health","author":"World Health Organization","year":"1949"},{"key":"e_1_2_9_106_1","first-page":"120","volume-title":"WHO Global Report on Trends in Prevalence of Tobacco Smoking 2000\u20132025","author":"World Health Organization","year":"2018"},{"key":"e_1_2_9_107_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2022.113818"},{"key":"e_1_2_9_108_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.5b03163"},{"key":"e_1_2_9_109_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2020.115437"},{"key":"e_1_2_9_110_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2009\u20100690"},{"key":"e_1_2_9_111_1","doi-asserted-by":"publisher","DOI":"10.1186\/1476\u2010069X\u201012\u201079"},{"key":"e_1_2_9_112_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2022.160651"},{"key":"e_1_2_9_113_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envres.2021.111977"},{"key":"e_1_2_9_114_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph182111055"},{"key":"e_1_2_9_115_1","doi-asserted-by":"publisher","DOI":"10.3760\/cma.j.issn.0253\u20109624.2018.10.010"},{"key":"e_1_2_9_116_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2024.01.111"}],"container-title":["Journal of Sleep Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jsr.70286","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jsr.70286","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jsr.70286","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T03:35:58Z","timestamp":1783913758000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jsr.70286"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,9]]},"references-count":115,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["10.1111\/jsr.70286"],"URL":"https:\/\/doi.org\/10.1111\/jsr.70286","archive":["Portico"],"relation":{},"ISSN":["0962-1105","1365-2869"],"issn-type":[{"value":"0962-1105","type":"print"},{"value":"1365-2869","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,9]]},"assertion":[{"value":"2025-06-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-09","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70286"}}