{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T04:02:11Z","timestamp":1785556931904,"version":"3.56.0"},"reference-count":69,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T00:00:00Z","timestamp":1785456000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T00:00:00Z","timestamp":1785456000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Sleep Research"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    The Maintenance of Wakefulness Test (MWT) is a widely used objective measure of daytime alertness, especially in patients with sleep disorders at increased risk of accidents. Anxiety and depression are common in this population and may influence subjective sleepiness and objective alertness. This study aimed to assess the relationship between acute emotional states, including state anxiety, as well as chronic anxiety and depression, with objective alertness measured by the MWT, alongside subjective sleepiness. In this prospective single\u2010centre study, 100 patients undergoing polysomnography and MWT completed validated questionnaires including the State (STAI\u2010A) and Trait (STAI\u2010B) Anxiety Inventory, Hospital Anxiety (HAD\u2010A) and Depression (HAD\u2010D) scale, Epworth Sleepiness Scale (ESS) and the Self\u2010Assessment Manikin (SAM) for acute emotional states. Correlations and regression analyses examined the relationships of anxiety, depression and emotional states with objective alertness and subjective sleepiness. The mean age was 44.8\u2009\u00b1\u200911.2\u2009years; 75% patients were treated for sleep apnea and 25% for central disorders of hypersomnolence. STAI\u2010B and HAD\u2010A showed mild negative correlations with mean sleep latency on MWT (\n                    <jats:italic>\u03c1<\/jats:italic>\n                    \u2248\u22120.21 to \u22120.25,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05), whereas STAI\u2010A, SAM and HAD\u2010D did not. STAI\u2010B, HAD\u2010A and HAD\u2010D positively correlated with subjective sleepiness (ESS) (\n                    <jats:italic>\u03c1<\/jats:italic>\n                    \u22480.23 to 0.38,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05). Univariate logistic regression identified STAI\u2010B but not STAI\u2010A as a significant independent predictor of MWT sleep onset among emotional, anxiety and depression variables. Chronic, but not acute, anxiety is linked to reduced residual objective alertness and increased subjective sleepiness, underscoring the need to assess and manage anxiety in patients with hypersomnolence.\n                  <\/jats:p>","DOI":"10.1111\/jsr.70423","type":"journal-article","created":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T03:19:56Z","timestamp":1785554396000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impaired Alertness Correlates With Chronic Anxiety: A Prospective Tertiary University Centre Cohort"],"prefix":"10.1111","author":[{"given":"Anice","family":"Borjon","sequence":"first","affiliation":[{"name":"Center for Sleep Medicine Croix\u2010Rousse Hospital, Hospices Civils de Lyon  Lyon France"},{"name":"UMRESTTE (Unit\u00e9 Mixte IFSTTAR\/UCBL) Universit\u00e9 Lyon 1  Lyon France"},{"name":"Service des Maladies Professionnelles Hospices Civils de Lyon, Centre Hospitalier Lyon Sud  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucie","family":"Bobin","sequence":"additional","affiliation":[{"name":"Center for Sleep Medicine Croix\u2010Rousse Hospital, Hospices Civils de Lyon  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois","family":"Ricordeau","sequence":"additional","affiliation":[{"name":"Center for Sleep Medicine Croix\u2010Rousse Hospital, Hospices Civils de Lyon  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas","family":"Marces","sequence":"additional","affiliation":[{"name":"Center for Sleep Medicine Croix\u2010Rousse Hospital, Hospices Civils de Lyon  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugo","family":"Fornelli","sequence":"additional","affiliation":[{"name":"Center for Sleep Medicine Croix\u2010Rousse Hospital, Hospices Civils de Lyon  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thierry","family":"Petitjean","sequence":"additional","affiliation":[{"name":"Center for Sleep Medicine Croix\u2010Rousse Hospital, Hospices Civils de Lyon  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amandine","family":"Viccica","sequence":"additional","affiliation":[{"name":"Center for Sleep Medicine Croix\u2010Rousse Hospital, Hospices Civils de Lyon  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Charbonnier","sequence":"additional","affiliation":[{"name":"Center for Sleep Medicine Croix\u2010Rousse Hospital, Hospices Civils de Lyon  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emeric","family":"Stauffer","sequence":"additional","affiliation":[{"name":"Center for Sleep Medicine Croix\u2010Rousse Hospital, Hospices Civils de Lyon  Lyon France"},{"name":"Laboratory LIBM EA7424, Team Vascular Biology and Red Blood Cell University of Lyon 1  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Charbotel","sequence":"additional","affiliation":[{"name":"UMRESTTE (Unit\u00e9 Mixte IFSTTAR\/UCBL) Universit\u00e9 Lyon 1  Lyon France"},{"name":"Service des Maladies Professionnelles Hospices Civils de Lyon, Centre Hospitalier Lyon Sud  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9067-8189","authenticated-orcid":false,"given":"Jacques","family":"Taillard","sequence":"additional","affiliation":[{"name":"Univ. Bordeaux, CNRS, SANPSY, UMR 6033  Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renaud","family":"Tamisier","sequence":"additional","affiliation":[{"name":"Grenoble Alpes University, HP2 Laboratory (Hypoxia Pathophysiology), INSERM U1300  Grenoble France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9938-9639","authenticated-orcid":false,"given":"Laure","family":"Peter\u2010Derex","sequence":"additional","affiliation":[{"name":"Center for Sleep Medicine Croix\u2010Rousse Hospital, Hospices Civils de Lyon  Lyon France"},{"name":"Lyon Neuroscience Research Center PAM Team, INSERM U1028\/CNRS UMR 5292\/Lyon 1 University  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Tank\u00e9r\u00e9","sequence":"additional","affiliation":[{"name":"Center for Sleep Medicine Croix\u2010Rousse Hospital, Hospices Civils de Lyon  Lyon France"},{"name":"Grenoble Alpes University, HP2 Laboratory (Hypoxia Pathophysiology), INSERM U1300  Grenoble France"},{"name":"Lyon Neuroscience Research Center PAM Team, INSERM U1028\/CNRS UMR 5292\/Lyon 1 University  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,31]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsr.13812"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/03610730500206808"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2023.04.007"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/28.11.1381"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/0013164402062004005"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resmer.2020.100787"},{"issue":"3","key":"e_1_2_10_8_1","first-page":"95","article-title":"The Comparison of Effects of State and Trait Anxiety on the Components of Sleep Quality","volume":"3","author":"Bavafa A.","year":"2018","journal-title":"Journal of Sleep Sciences"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41562\u2010019\u20100754\u20108"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.6576"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2024.1431821"},{"issue":"4","key":"e_1_2_10_12_1","first-page":"386","article-title":"Impact of Motivation on Multiple Sleep Latency Test and Maintenance of Wakefulness Test Measurements","volume":"1","author":"Bonnet M. 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