{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T16:10:03Z","timestamp":1787501403268,"version":"build-2736575974"},"reference-count":24,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,12,8]],"date-time":"2022-12-08T00:00:00Z","timestamp":1670457600000},"content-version":"vor","delay-in-days":3597,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["jthjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Thrombosis and Haemostasis"],"published-print":{"date-parts":[[2013,2]]},"DOI":"10.1111\/jth.12102","type":"journal-article","created":{"date-parts":[[2012,12,20]],"date-time":"2012-12-20T21:16:42Z","timestamp":1356038202000},"page":"315-324","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"title":["Effect of warfarin treatment on thrombin activatable fibrinolysis inhibitor (TAFI) activation and TAFI\u2010mediated inhibition of fibrinolysis"],"prefix":"10.1016","volume":"11","author":[{"given":"F.","family":"Incampo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Carrieri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Galasso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.A.","family":"Scaraggi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Di Serio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Woodhams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Semeraro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Colucci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1111\/jth.12102_bb0010","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.thromres.2011.10.031","article-title":"Thrombin activatable fibrinolysis inhibitor: at the nexus of fibrinolysis and inflammation","volume":"129","author":"Colucci","year":"2012","journal-title":"Thromb Res"},{"key":"10.1111\/jth.12102_bb0015","doi-asserted-by":"crossref","first-page":"2511","DOI":"10.1161\/01.ATV.20.12.2511","article-title":"Thrombin activatable fibrinolysis inhibitor and an antifibrinolytic pathway","volume":"20","author":"Bajzar","year":"2000","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1111\/jth.12102_bb0020","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.1046\/j.1538-7836.2003.00329.x","article-title":"Thrombin\u2010activatable fibrinolysis inhibitor (TAFI, plasma procarboxypeptidase B, procarboxypeptidase R, procarboxypeptidase U)","volume":"1","author":"Bouma","year":"2003","journal-title":"J Thromb Haemost"},{"key":"10.1111\/jth.12102_bb0025","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1097\/00001721-200309000-00007","article-title":"Enhancement of fibrinolytic potential in vitro by anticoagulant drugs targeting activated factor X, but not by those inhibiting thrombin or tissue factor","volume":"14","author":"Lisman","year":"2003","journal-title":"Blood Coagul Fibrinolysis"},{"key":"10.1111\/jth.12102_bb0030","doi-asserted-by":"crossref","first-page":"160S","DOI":"10.1378\/chest.08-0670","article-title":"Pharmacology and management of the Vitamin K Antagonists: American College of Chest Physicians Evidence\u2010Based Clinical Practice Guidelines (8th Edition)","volume":"133","author":"Ansell","year":"2008","journal-title":"Chest"},{"key":"10.1111\/jth.12102_bb0035","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1172\/JCI113239","article-title":"Suppression of hemostatic system activation by oral anticoagulants in the blood of patients with thrombotic diatheses","volume":"80","author":"Conway","year":"1987","journal-title":"J Clin Invest"},{"key":"10.1111\/jth.12102_bb0040","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/S0049-3848(00)00203-6","article-title":"Correlation between different intensities of anti\u2010vitamin K treatment and coagulation parameters","volume":"98","author":"Jerkeman","year":"2000","journal-title":"Thromb Res"},{"key":"10.1111\/jth.12102_bb0045","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1055\/s-0038-1657557","article-title":"Thrombin, thrombomodulin and TAFI in the molecular link between coagulation and fibrinolysis","volume":"78","author":"Nesheim","year":"1997","journal-title":"Thromb Haemost"},{"key":"10.1111\/jth.12102_bb0050","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1055\/s-0037-1616530","article-title":"The defective down regulation of fibrinolysis in haemophilia A can be restored by increasing the TAFI plasma concentration","volume":"86","author":"Mosnier","year":"2001","journal-title":"Thromb Haemost"},{"key":"10.1111\/jth.12102_bb0055","doi-asserted-by":"crossref","first-page":"2323","DOI":"10.1172\/JCI119412","article-title":"Thrombin\u2010mediated activation of factor XI results in a thrombin\u2010activatable fibrinolysis inhibitor\u2010dependent inhibition of fibrinolysis","volume":"99","author":"von dem Borne","year":"1997","journal-title":"J Clin Invest"},{"key":"10.1111\/jth.12102_bb0060","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1111\/j.1538-7836.2004.00605.x","article-title":"Carboxypeptidase U (TAFIa) prevents lysis from proceeding into the propagation phase through a threshold\u2010dependent mechanism","volume":"2","author":"Leurs","year":"2004","journal-title":"J Thromb Haemost"},{"key":"10.1111\/jth.12102_bb0065","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1053\/gast.2001.25481","article-title":"Thrombin\u2010activatable fibrinolysis inhibitor deficiency in cirrhosis is not associated with increased plasma fibrinolysis","volume":"121","author":"Lisman","year":"2001","journal-title":"Gastroenterology"},{"key":"10.1111\/jth.12102_bb0070","doi-asserted-by":"crossref","first-page":"1976","DOI":"10.1182\/blood.V74.6.1976.1976","article-title":"Thrombin infusion in endotoxin\u2010treated rabbits reduces the plasma levels of plasminogen activator inhibitor: evidence for a protein\u2010C\u2010mediated mechanism","volume":"74","author":"Colucci","year":"1989","journal-title":"Blood"},{"key":"10.1111\/jth.12102_bb0075","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/0049-3848(80)90359-X","article-title":"Cancer cell procoagulant activity: evaluation by an amidolytic assay","volume":"18","author":"Colucci","year":"1980","journal-title":"Thromb Res"},{"key":"10.1111\/jth.12102_bb0080","doi-asserted-by":"crossref","first-page":"2157","DOI":"10.1182\/blood-2003-06-2169","article-title":"Hyperprothrombinemia associated with prothrombin G20210A mutation inhibits plasma fibrinolysis through a TAFI\u2010mediated mechanism","volume":"103","author":"Colucci","year":"2004","journal-title":"Blood"},{"key":"10.1111\/jth.12102_bb0085","doi-asserted-by":"crossref","first-page":"2351","DOI":"10.1111\/j.1538-7836.2005.01600.x","article-title":"Inhibition of thrombin activatable fibrinolysis inhibitor augments fibrinolysis in human whole blood","volume":"3","author":"Cruden","year":"2005","journal-title":"J Thromb Haemost"},{"key":"10.1111\/jth.12102_bb0090","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1111\/j.1538-7836.2010.04120.x","article-title":"The role of thrombin activatable fibrinolysis inhibitor and factor XI in platelet\u2010mediated fibrinolysis resistance: a thromboelastographic study in whole blood","volume":"9","author":"Carrieri","year":"2011","journal-title":"J Thromb Haemost"},{"key":"10.1111\/jth.12102_bb0095","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.atherosclerosis.2011.09.035","article-title":"Trunk weighted obesity, cholesterol levels and low grade inflammation are main determinants for enhanced thrombin generation","volume":"220","author":"Pr\u00fcller","year":"2012","journal-title":"Atherosclerosis"},{"key":"10.1111\/jth.12102_bb0100","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1055\/s-0038-1646904","article-title":"The relative importance of the factors II, VII, IX and X for the prothrombinase activity in plasma of orally anticoagulated patients","volume":"62","author":"Xi","year":"1989","journal-title":"Thromb Haemost"},{"key":"10.1111\/jth.12102_bb0105","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1182\/blood-2010-02-267740","article-title":"Venous thrombosis risk associated with plasma hypofibrinolysis is explained by elevated plasma levels of TAFI and PAI\u20101","volume":"116","author":"Meltzer","year":"2010","journal-title":"Blood"},{"key":"10.1111\/jth.12102_bb0110","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1111\/j.1538-7836.2007.02426.x","article-title":"The relative kinetics of clotting and lysis provide a biochemical rationale for the correlation between elevated fibrinogen and cardiovascular disease","volume":"5","author":"Kim","year":"2007","journal-title":"J Thromb Haemost"},{"key":"10.1111\/jth.12102_bb0115","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1111\/j.1749-6632.1992.tb51599.x","article-title":"Lysis of platelet\u2010rich thrombi: the role of PAI\u20101","volume":"667","author":"Booth","year":"1992","journal-title":"Ann N Y Acad Sci"},{"key":"10.1111\/jth.12102_bb0120","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1182\/blood.V83.2.351.351","article-title":"Platelets inhibit fibrinolysis in vitro by both plasminogen activator inhibitor\u20101\u2010dependent and \u2010independent mechanisms","volume":"83","author":"Fay","year":"1994","journal-title":"Blood"},{"key":"10.1111\/jth.12102_bb0125","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1182\/blood-2004-08-3253","article-title":"Reduced plasma fibrinolytic potential is a risk factor for venous thrombosis","volume":"105","author":"Lisman","year":"2005","journal-title":"Blood"}],"container-title":["Journal of Thrombosis and Haemostasis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjth.12102","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjth.12102","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1538783622111372?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1538783622111372?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/jth.12102\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T03:06:41Z","timestamp":1761534401000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1538783622111372"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2]]},"references-count":24,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,2]]}},"alternative-id":["S1538783622111372"],"URL":"https:\/\/doi.org\/10.1111\/jth.12102","relation":{},"ISSN":["1538-7836"],"issn-type":[{"value":"1538-7836","type":"print"}],"subject":[],"published":{"date-parts":[[2013,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of warfarin treatment on thrombin activatable fibrinolysis inhibitor (TAFI) activation and TAFI\u2010mediated inhibition of fibrinolysis","name":"articletitle","label":"Article Title"},{"value":"Journal of Thrombosis and Haemostasis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1111\/jth.12102","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 International Society on Thrombosis and Haemostasis. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}