{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:42:14Z","timestamp":1761561734785},"reference-count":27,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2013,3,20]],"date-time":"2013-03-20T00:00:00Z","timestamp":1363737600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Viral Hepatitis"],"published-print":{"date-parts":[[2013,9]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Morbidity and mortality due to hepatitis C (<jats:styled-content style=\"fixed-case\">HCV<\/jats:styled-content>) infection are rising in the United States as the highest risk cohort (those born between 1945 and 1965) ages. It is important for governments and healthcare providers to have timely, readily obtainable data to estimate the burden of <jats:styled-content style=\"fixed-case\">HCV<\/jats:styled-content> locally. Demographic factors, hospital charges and comorbid conditions were summarized for Los Angeles County (<jats:styled-content style=\"fixed-case\">LAC<\/jats:styled-content>) residents who had at least one hospitalization in California during 2007\u20132009 with <jats:styled-content style=\"fixed-case\">HCV<\/jats:styled-content> as a primary or secondary diagnosis using statewide hospital discharge data. Logistic regression was used to estimate odds ratios for factors associated with dying during hospitalization. A total of 19\u00a0907 unique patients were hospitalized with <jats:styled-content style=\"fixed-case\">HCV<\/jats:styled-content> during the 3\u2010year study period; 63.0% were aged 45\u201365\u00a0years; 1874 (9.4%) died. Hospitalizations for <jats:styled-content style=\"fixed-case\">HCV<\/jats:styled-content> doubled during this time period. Total charges for hospitalizations for which <jats:styled-content style=\"fixed-case\">HCV<\/jats:styled-content> was coded as the principal diagnosis increased from $18 million to $58 million, with over 70% charged to government sources. After adjusting for demographic factors, human immunodeficiency virus (<jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>) and hepatitis B (<jats:styled-content style=\"fixed-case\">HBV<\/jats:styled-content>), current alcohol abuse and kidney disease were associated with dying during hospitalization. Based on statewide hospital discharge data, morbidity and mortality from <jats:styled-content style=\"fixed-case\">HCV<\/jats:styled-content> infections increased in <jats:styled-content style=\"fixed-case\">LAC<\/jats:styled-content> from 2007\u20132009, and pose an economic burden to government. To lower mortality risk, <jats:styled-content style=\"fixed-case\">HCV<\/jats:styled-content> patients should be referred for follow\u2010up. The expected increase in <jats:styled-content style=\"fixed-case\">HCV<\/jats:styled-content> hospitalizations as infected patients' age poses an increasing burden to healthcare systems.<\/jats:p>","DOI":"10.1111\/jvh.12086","type":"journal-article","created":{"date-parts":[[2013,3,21]],"date-time":"2013-03-21T02:50:05Z","timestamp":1363834205000},"page":"628-637","source":"Crossref","is-referenced-by-count":8,"title":["Hospitalizations due to hepatitis <scp>C<\/scp> in <scp>L<\/scp>os <scp>A<\/scp>ngeles <scp>C<\/scp>ounty, 2007\u20132009: case characteristics and factors associated with mortality"],"prefix":"10.1111","volume":"20","author":[{"given":"L.","family":"Sie","sequence":"first","affiliation":[{"name":"Acute Communicable Disease Control Los Angeles County Department of Public Health Los Angeles CA USA"},{"name":"University of California School of Public Health Berkeley CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N. M.","family":"Gatto","sequence":"additional","affiliation":[{"name":"Acute Communicable Disease Control Los Angeles County Department of Public Health Los Angeles CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Bancroft","sequence":"additional","affiliation":[{"name":"Acute Communicable Disease Control Los Angeles County Department of Public Health Los Angeles CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,3,20]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2010.12.032"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.22165"},{"key":"e_1_2_8_4_1","unstructured":"Acute Communicable Disease Control Department of Public Health Los Angeles County. Hepatitis C in Los Angeles County. Available at:http:\/\/publichealth.lacounty.gov\/acd\/Diseases\/HepC.htm(accessed 24 July 2012)."},{"key":"e_1_2_8_5_1","unstructured":"Centers for Disease Control and Prevention.Hepatitis C Information For the Health Professional. Available at:http:\/\/www.cdc.gov\/hepatitis\/HCV\/index.htm(accessed 22 July 2012)."},{"key":"e_1_2_8_6_1","unstructured":"The C. Everett Koop Institute Dartmouth Medical School.Hepatitis C: The Facts: The Epidemic \u2013 Prevalence \u2013 United StatesAvailable at:http:\/\/www.epidemic.org\/theFacts\/theEpidemic\/USPrevalence(accessed 24 July 2012)."},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1478-3231.2008.01945.x"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.15.4993"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.52.1.126"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/003335491112600607"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0b013e3181fdef1d"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2010.09-0494"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00038-009-0076-0"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0001480"},{"key":"e_1_2_8_15_1","unstructured":"Los Angeles County Department of Public Health Office of Health Assessment and Epidemiology.Mortality in Los Angeles County 2008: Leading causes of death and premature death with trends for 1999\u20102008. 2011Available at:http:\/\/publichealth.lacounty.gov\/docs\/mortality2008-dec2011.pdf(accessed 24 July 2012)."},{"key":"e_1_2_8_16_1","unstructured":"California Inpatient Data Reporting Manual Medical Information Reporting for California. Available at:http:\/\/www.oshpd.ca.gov\/hid\/mircal\/Text_pdfs\/ManualsGuides\/IPManual\/Intro.pdf."},{"key":"e_1_2_8_17_1","volume-title":"Databases and related tools from the healthcare cost and utilization project (HCUP)","author":"US Department of Health & Human Services Agency for Healthcare Research and Quality","year":"2011"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(03)00828-X"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1159\/000333772"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1530-0277.2006.00304.x"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1177\/003335491012500310"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cis628"},{"key":"e_1_2_8_23_1","unstructured":"Key Indicators of Health by Service Planning Area.2009. Available at:http:\/\/publichealth.lacounty.gov\/wwwfiles\/ph\/hae\/ha\/KIR_2009_FINALr1.pdf(accessed 24 July 2012)."},{"key":"e_1_2_8_24_1","unstructured":"Veteran's Administration. Veteran Population Population Tables by Counties Living: Available at:http:\/\/www.va.gov\/vetdata\/Veteran_Population.asp."},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.24618"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.respe.2009.02.206"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/QMH.0b013e3181ccbd07"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2007.03572.x"}],"container-title":["Journal of Viral Hepatitis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjvh.12086","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjvh.12086","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jvh.12086","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T08:06:55Z","timestamp":1696234015000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jvh.12086"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3,20]]},"references-count":27,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2013,9]]}},"alternative-id":["10.1111\/jvh.12086"],"URL":"https:\/\/doi.org\/10.1111\/jvh.12086","archive":["Portico"],"relation":{},"ISSN":["1352-0504","1365-2893"],"issn-type":[{"value":"1352-0504","type":"print"},{"value":"1365-2893","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,3,20]]}}}