{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T11:49:13Z","timestamp":1790250553300,"version":"4.1.0"},"reference-count":9,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2014,7,9]],"date-time":"2014-07-09T00:00:00Z","timestamp":1404864000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Institut National de Recherche Medical"},{"name":"Agence Nationale de Recherches sur le SIDA et les h\u00e9patites virales"},{"name":"Bahia\u2032s State Research Foundation"},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cientifico e Tecnologico","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Viral Hepatitis"],"published-print":{"date-parts":[[2014,12]]},"abstract":"Summary<\/jats:title>\n \n HDV<\/jats:styled-content>\n infection still remains a serious public health problem in\n A<\/jats:styled-content>\n mazonia. There are few data regarding the biomolecular aspects of\n HBV<\/jats:styled-content>\n \/\n HDV<\/jats:styled-content>\n co\u2010infection in this region. We studied 92 patients\n HB<\/jats:styled-content>\n sAg\n +<\/jats:sup>\n \/anti\u2010\n HDV<\/jats:styled-content>\n IgG\n +<\/jats:sup>\n followed at the\n H<\/jats:styled-content>\n epatitis\n R<\/jats:styled-content>\n eferral\n C<\/jats:styled-content>\n enters of\n P<\/jats:styled-content>\n orto\n V<\/jats:styled-content>\n elho (\n RO<\/jats:styled-content>\n ),\n R<\/jats:styled-content>\n io\n B<\/jats:styled-content>\n ranco and\n C<\/jats:styled-content>\n ruzeiro do\n S<\/jats:styled-content>\n ul (\n AC<\/jats:styled-content>\n ),\n B<\/jats:styled-content>\n razil, from\n M<\/jats:styled-content>\n arch 2006 to\n M<\/jats:styled-content>\n arch 2007 for whom the\n HDV<\/jats:styled-content>\n and\/or the\n HBV<\/jats:styled-content>\n genotype could be determined. The\n HDV<\/jats:styled-content>\n genotype could be determined in 90 patients, while the\n HBV<\/jats:styled-content>\n genotypes could be positively determined in 74.\n HBV<\/jats:styled-content>\n subgenotype F2 is the most prevalent (40.2%), followed by the subgenotypes A1 (15.2%) and D3 (8.7%), while 16.4% were other subgenotypes or genotypes, 4.3% were discordant and 15.2% were unamplifiable. Surprisingly,\n HDV<\/jats:styled-content>\n genotype 3 (\n HDV<\/jats:styled-content>\n \u20103) was found in all of the\n HBV<\/jats:styled-content>\n \/\n HDV<\/jats:styled-content>\n \u2010infected patients that could be genotyped for\n HDV<\/jats:styled-content>\n , confirming that\n HDV<\/jats:styled-content>\n \u20103 can associate with non\u2010F\n HBV<\/jats:styled-content>\n genotypes. However, a\n HDV<\/jats:styled-content>\n \u20103 mutant was found in 29.3% of patients and was more frequently associated with non\u2010F\n HBV<\/jats:styled-content>\n genotypes (\n P<\/jats:italic>\n \u00a0<\u00a00.001) than were nonmutant strains, suggesting that the mutation may facilitate association of\n HDV<\/jats:styled-content>\n \u20103 with non\u2010F\n HBV<\/jats:styled-content>\n genotypes.\n <\/jats:p>","DOI":"10.1111\/jvh.12267","type":"journal-article","created":{"date-parts":[[2014,7,9]],"date-time":"2014-07-09T02:48:58Z","timestamp":1404874138000},"page":"921-924","source":"Crossref","is-referenced-by-count":18,"title":["HBV<\/scp>\n \/\n HDV<\/scp>\n co\u2010infection in the\n W<\/scp>\n estern\n B<\/scp>\n razilian\n A<\/scp>\n mazonia: an intriguing mutation among\n HDV<\/scp>\n genotype 3 carriers"],"prefix":"10.1111","volume":"21","author":[{"given":"A.","family":"Kay","sequence":"first","affiliation":[{"name":"INSERM, U1052 Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Melo da Silva","sequence":"additional","affiliation":[{"name":"INSERM, U1052 Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Pedreira","sequence":"additional","affiliation":[{"name":"Laboratory of Pathology and Molecular Biology CPqGM\/FIOCRUZ Salvador Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Negreiros","sequence":"additional","affiliation":[{"name":"Acre State Secretariat of Health Rio Branco Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Lobato","sequence":"additional","affiliation":[{"name":"Acre State Secretariat of Health Rio Branco Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"Braga","sequence":"additional","affiliation":[{"name":"Institute of Tropical Medicine of Amazonas Manaus Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Muwonge","sequence":"additional","affiliation":[{"name":"International Agency for Research on Cancer (IARC)\/World Health Organization (WHO) Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"D\u00e9ny","sequence":"additional","affiliation":[{"name":"INSERM, U1052 Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Reis","sequence":"additional","affiliation":[{"name":"Laboratory of Pathology and Molecular Biology CPqGM\/FIOCRUZ Salvador Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Zoulim","sequence":"additional","affiliation":[{"name":"INSERM, U1052 Lyon France"},{"name":"Service d'H\u00e9pato\u2010Gastroent\u00e9rology H\u00f4pital de la Croix\u2010Rousse Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Trepo","sequence":"additional","affiliation":[{"name":"INSERM, U1052 Lyon France"},{"name":"Service d'H\u00e9pato\u2010Gastroent\u00e9rology H\u00f4pital de la Croix\u2010Rousse Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"A.","family":"D'Oliveira","sequence":"additional","affiliation":[{"name":"University Hospital Federal University of Bahia Amazon Hepatitis Group Salvador Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. M.","family":"Salcedo","sequence":"additional","affiliation":[{"name":"Federal University of Rond\u00f4nia Porto Velho Brazil"},{"name":"FIOCRUZ\u2010RO Porto Velho Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. I.","family":"Schinoni","sequence":"additional","affiliation":[{"name":"University Hospital Federal University of Bahia Amazon Hepatitis Group Salvador Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Parana","sequence":"additional","affiliation":[{"name":"Laboratory of Pathology and Molecular Biology CPqGM\/FIOCRUZ Salvador Brazil"},{"name":"University Hospital Federal University of Bahia Amazon Hepatitis Group Salvador Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,7,9]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/174.5.920"},{"issue":"3","key":"e_1_2_8_3_1","doi-asserted-by":"crossref","first-page":"475","DOI":"10.4269\/ajtmh.2006.75.475","article-title":"HDV genotypes in the Western Brazilian Amazon region: a preliminary report","volume":"75","author":"Parana R","year":"2006","journal-title":"Am J Trop Med Hyg"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1987.03400040077025"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-82-9-2183"},{"key":"e_1_2_8_6_1","first-page":"451","article-title":"Studies on the role of HDV in an outbreak of fulminant hepatitis in Bangui (Central African Republic)","volume":"234","author":"Lesbordes JL","year":"1987","journal-title":"Prog Clin Biol Res"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1261\/rna.1504009"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.013615-0"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2008.02.009"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/323508a0"}],"container-title":["Journal of Viral Hepatitis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjvh.12267","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjvh.12267","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jvh.12267","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T09:04:00Z","timestamp":1695459840000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jvh.12267"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7,9]]},"references-count":9,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["10.1111\/jvh.12267"],"URL":"https:\/\/doi.org\/10.1111\/jvh.12267","archive":["Portico"],"relation":{},"ISSN":["1352-0504","1365-2893"],"issn-type":[{"value":"1352-0504","type":"print"},{"value":"1365-2893","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,7,9]]}}}