{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:45:10Z","timestamp":1788871510095,"version":"build-2803163510"},"reference-count":29,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2014,8,20]],"date-time":"2014-08-20T00:00:00Z","timestamp":1408492800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Chinese National Science and Technology Major Project","award":["2012ZX10002003"],"award-info":[{"award-number":["2012ZX10002003"]}]},{"name":"Chinese National Science and Technology Major Project","award":["2013ZX10002008"],"award-info":[{"award-number":["2013ZX10002008"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81202377"],"award-info":[{"award-number":["81202377"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81273334"],"award-info":[{"award-number":["81273334"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Viral Hepatitis"],"published-print":{"date-parts":[[2014,12]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    Hepatitis B is a very common communicable disease in China but the prevalence of hepatitis B virus (\n                    <jats:styled-content style=\"fixed-case\">HBV<\/jats:styled-content>\n                    ) infection in patients with autoimmune diseases is unknown. We retrospectively investigated the prevalence of autoimmune diseases in patients with\n                    <jats:styled-content style=\"fixed-case\">HBV<\/jats:styled-content>\n                    infection. The medical records of 4060 patients with autoimmune or nonautoimmune diseases were reviewed. A positive test result for hepatitis B surface antigen (\n                    <jats:styled-content style=\"fixed-case\">HB<\/jats:styled-content>\n                    sAg) was used to indicate the presence of\n                    <jats:styled-content style=\"fixed-case\">HBV<\/jats:styled-content>\n                    infection. Autoimmune diseases included autoimmune hepatitis, primary biliary cirrhosis, systemic lupus erythematosus and ulcerative colitis. Nonautoimmune conditions included inguinal hernia, appendicitis and pregnant or postpartum women. The proportion of autoimmune disease patients who were\n                    <jats:styled-content style=\"fixed-case\">HB<\/jats:styled-content>\n                    sAg positive (2.24%) was significantly lower than that of nonautoimmune disease patients who were\n                    <jats:styled-content style=\"fixed-case\">HB<\/jats:styled-content>\n                    sAg positive (4.58%;\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0=\u00a00.0014). Regarding hepatic autoimmune diseases, the positivity rates for\n                    <jats:styled-content style=\"fixed-case\">HB<\/jats:styled-content>\n                    sAg in autoimmune hepatitis patients (0.83%) and primary biliary cirrhosis patients (1.02%) were both significantly lower than in nonautoimmune patients (4.58%;\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0=\u00a00.006 and 0.004, respectively). Patients with hepatic autoimmune disease were significantly less likely to be\n                    <jats:styled-content style=\"fixed-case\">HB<\/jats:styled-content>\n                    sAg positive (0.93%) than patients with non\u2010hepatic autoimmune disease (3.99%;\n                    <jats:italic>P\u00a0<\/jats:italic>\n                    =\n                    <jats:italic>\u00a0<\/jats:italic>\n                    0.002). Patients with autoimmune diseases, especially those with hepatic autoimmune disease, may more efficiently clear\n                    <jats:styled-content style=\"fixed-case\">HBV<\/jats:styled-content>\n                    than patients with nonautoimmune diseases.\n                  <\/jats:p>","DOI":"10.1111\/jvh.12302","type":"journal-article","created":{"date-parts":[[2014,8,20]],"date-time":"2014-08-20T04:11:32Z","timestamp":1408507892000},"page":"925-929","source":"Crossref","is-referenced-by-count":17,"title":["Low prevalence of hepatitis B virus infection in patients with autoimmune diseases in a Chinese patient population"],"prefix":"10.1111","volume":"21","author":[{"given":"M.","family":"Sui","sequence":"first","affiliation":[{"name":"Department of Hepatology First Hospital of Jilin University Changchun China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Hepatology First Hospital of Jilin University Changchun China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X.","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Heilongjiang Province Hospital Harbin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Sixth Hospital of Hangzhou Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Epidemiology First Hospital of Jilin University Changchun China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Yang","sequence":"additional","affiliation":[{"name":"Academy of Translational Medicine First Hospital of Jilin University Changchun 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