{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T11:18:57Z","timestamp":1696331937207},"reference-count":52,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2014,10,21]],"date-time":"2014-10-21T00:00:00Z","timestamp":1413849600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Viral Hepatitis"],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:label \/><jats:p>With the advent of direct\u2010acting antivirals (DAAs), the treatment of chronic hepatitis C virus (HCV) infection (CHC) has been revolutionized. Modern interferon\u2010 and potentially also ribavirin\u2010free combinations consisting of 2 or 3 direct\u2010acting antivirals (DAA) promise sustained virological response rates (SVR) of above 90%. This coincides with much shorter treatment durations and a much more favorable toxicity profile. Some DAAs even work across all HCV genotypes (pangenotypic) [<jats:italic>BMJ<\/jats:italic>, 349, 2014, g3308]. And lastly, HCV treatment in HIV\u2010coinfected patients will no longer differ from HCV\u2010monoinfected patients as response rates under DAA in the setting of HCV\u2013HIV coinfection have been as good as in HCV\u2010monoinfected patients [<jats:italic>J Hepatol<\/jats:italic>, 61, 2014, 373]. Only drug\u2013drug interactions with the new DAAs and concomitant antiretroviral therapy have to be accounted for due to shared metabolization pathways via the cytochrome p450 system.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jvh.12348","type":"journal-article","created":{"date-parts":[[2014,10,21]],"date-time":"2014-10-21T11:26:41Z","timestamp":1413890801000},"page":"2-7","source":"Crossref","is-referenced-by-count":6,"title":["How will we manage acute <scp>HCV<\/scp> in men having sex with men in the era of all oral therapy?"],"prefix":"10.1111","volume":"22","author":[{"given":"C.","family":"Boesecke","sequence":"first","affiliation":[{"name":"Department of Internal Medicine I Bonn University Hospital Bonn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. K.","family":"Rockstroh","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine I Bonn University Hospital Bonn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,10,21]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.g3308"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2014.05.001"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1086\/600058"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/sti.2007.027334"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.2807\/esm.10.05.00535-en"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e32832e5631"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1086\/431486"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1086\/596770"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365548.2010.524660"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.06014-11"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e3283471cce"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.22759"},{"key":"e_1_2_7_14_1","unstructured":"NelsonM 10th Co\u2010Infection Workshop 2014 June 12\u201013 Paris France."},{"key":"e_1_2_7_15_1","unstructured":"McFaulKet\u00a0al.Acute hepatitis C infection in HIV\u2010negative men who have sex with men. 3rd Joint BHIVA\/BASHH Conference 3\u20106 April 2014 Liverpool. Poster abstract 384."},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0028-1109149"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e32831940a3"},{"issue":"4","key":"e_1_2_7_18_1","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1097\/QAD.0b013e328343443b","article-title":"Acute hepatitis C in HIV\u2010infected individuals: recommendations from the European AIDS Treatment Network (NEAT) consensus conference","volume":"25","author":"The European AIDS Treatment Network (NEAT) Acute Hepatitis C Infection Consensus Panel","year":"2011","journal-title":"AIDS"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2362.2007.01753.x"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1086\/592171"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.23850"},{"key":"e_1_2_7_22_1","unstructured":"JonesL UrielA KaplanDet\u00a0al.Natural history and treatment outcome of acute hepatitis C with and without HIV co\u2010infection in a North American cohort. In: AASLD 2008 Meeting; San Francisco USA; 2008; abstract 1838."},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2010.217166"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.284.4.450"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/QCO.0b013e3283422e09"},{"key":"e_1_2_7_26_1","unstructured":"VogelM PageE MatthewsGet\u00a0al.Use of week 4 HCV RNA after acute HCV infection to predict chronic HCV infection. In: 17th Conference on Retroviruses and Opportunistic Infections; San Francisco California USA; 2010; abstract 640."},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.qai.0000191281.77954.27"},{"key":"e_1_2_7_28_1","unstructured":"FiererD FishmanS UrielAet\u00a0al.Characterization of an outbreak of acute HCV infection in HIV\u2010infected men in New York city. In: 16th Conference on Retroviruses and Opportunistic Infections; Montreal Canada; 2009; abstract 802."},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.qai.0000174930.64145.a9"},{"key":"e_1_2_7_30_1","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1177\/135965350601100817","article-title":"Pegylated interferon\u2010alpha for the treatment of sexually transmitted acute hepatitis C in HIV\u2010infected individuals","volume":"11","author":"Vogel M","year":"2006","journal-title":"Antivir Ther"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e328330ed24"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.aids.0000226956.02719.fd"},{"key":"e_1_2_7_33_1","unstructured":"KrukA.Efficacy of acute HCV treatment with peg\u2010interferon alfa\u20102b and ribavirin in HIV\u2010infected patients. In: 3rd International AIDS Society Conference on HIV Pathogenesis and Treatment; Rio de Janeiro; 2005; abstract TuPe1.C01."},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.aids.0000200541.40633.56"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.23959"},{"issue":"1","key":"e_1_2_7_36_1","first-page":"43","article-title":"Treatment of acute hepatitis C virus infection in HIV+ patients: dutch recommendations for management","volume":"69","author":"Arends JE","year":"2011","journal-title":"Neth J Med"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e3283553719"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.3851\/IMP1501"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e3283480144"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2009.09.019"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.24152"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2011.08.020"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1097\/COH.0b013e32834732cd"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cit799"},{"key":"e_1_2_7_45_1","unstructured":"HullegieS.10th Co\u2010Infection Workshop 2014 #O_02"},{"key":"e_1_2_7_46_1","unstructured":"BoeseckeC.Acute HCV Treatment \u2010 European Perspective. International HIV\/Viral Hepatitis Co\u2010Infection Satellite Meeting July 18\u201019 2014 Melbourne Australia."},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2014.05.010"},{"issue":"4","key":"e_1_2_7_48_1","article-title":"Increases in acute hepatitis C (HCV) incidence across Europe: which regions and patient groups are affected?","volume":"15","author":"Rockstroh J","year":"2012","journal-title":"J Int AIDS Soc"},{"key":"e_1_2_7_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/hiv.12127"},{"key":"e_1_2_7_50_1","unstructured":"BoeseckeC IngilizP MandorferM.Is there Long\u2010term Evidence of Advanced Liver Fibrosis after Acute Hepatitis C in HIV Coinfection?Conference on Retrovirus and Opportunistic Infections (CROI) March 3\u20106 2014 Abstract #1396 Poster #644."},{"key":"e_1_2_7_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2010.08.029"},{"key":"e_1_2_7_52_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.27194"},{"key":"e_1_2_7_53_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvh.12249"}],"container-title":["Journal of Viral Hepatitis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjvh.12348","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjvh.12348","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jvh.12348","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T12:30:49Z","timestamp":1696249849000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jvh.12348"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10,21]]},"references-count":52,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["10.1111\/jvh.12348"],"URL":"https:\/\/doi.org\/10.1111\/jvh.12348","archive":["Portico"],"relation":{},"ISSN":["1352-0504","1365-2893"],"issn-type":[{"value":"1352-0504","type":"print"},{"value":"1365-2893","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,10,21]]}}}