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During follow\u2010up, 13 (19.1%) of the 68 patients died of complications related to their oncohaematological disease, and 3 (4%) showed a virological <jats:styled-content style=\"fixed-case\">HBV<\/jats:styled-content> reactivation (retroconversion to <jats:styled-content style=\"fixed-case\">HB<\/jats:styled-content>sAg positivity) 1\u20107\u00a0months after the discontinuation of lamivudine prophylaxis (2 treated for chronic lymphocytic leukaemia and one for Waldenstrom's disease); of these, 2 showed a biochemical reactivation. Comparing the demographic and clinical characteristics of the 3 patients with a virological <jats:styled-content style=\"fixed-case\">HBV<\/jats:styled-content> reactivation to the 65 without, the former were older (median age and range: 67\u00a0years [75\u201078] vs. 61 [24\u201088]; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.05) and were less frequently treated for B\u2010cell non\u2010Hodgkin lymphoma (B\u2010<jats:styled-content style=\"fixed-case\">NHL<\/jats:styled-content>) (0 vs. 70.7%, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.03). In conclusion, a 18\u00a0months of lamivudine prophylaxis was effective in preventing <jats:styled-content style=\"fixed-case\">HBV<\/jats:styled-content> reactivation in <jats:styled-content style=\"fixed-case\">HB<\/jats:styled-content>sAg\u2010negative\/anti\u2013<jats:styled-content style=\"fixed-case\">HB<\/jats:styled-content>c\u2010positive patients treated for B\u2010<jats:styled-content style=\"fixed-case\">NHL<\/jats:styled-content>. However, in patients with chronic and severe immunodepression, such as those with chronic lymphocytic leukaemia and Waldenstrom's disease, prophylaxis should be continued for an indefinite period.<\/jats:p>","DOI":"10.1111\/jvh.12802","type":"journal-article","created":{"date-parts":[[2017,10,13]],"date-time":"2017-10-13T17:12:43Z","timestamp":1507914763000},"page":"198-204","source":"Crossref","is-referenced-by-count":14,"title":["Eighteen\u2010month lamivudine prophylaxis on preventing occult hepatitis B virus infection reactivation in patients with haematological malignancies receiving immunosuppression therapy"],"prefix":"10.1111","volume":"25","author":[{"given":"A.","family":"Marrone","sequence":"first","affiliation":[{"name":"Department of Medical, Surgical, Neurological, Metabolic and Aging Sciences University of Campania \u201cLuigi Vanvitelli\u201d  Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Capoluongo","sequence":"additional","affiliation":[{"name":"Department of Mental Health and Public Medicine University of Campania, Luigi Vanvitelli  Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"D'Amore","sequence":"additional","affiliation":[{"name":"Department of Medical, Surgical, Neurological, Metabolic and Aging Sciences University of Campania \u201cLuigi Vanvitelli\u201d  Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Pisaturo","sequence":"additional","affiliation":[{"name":"Department of Mental Health and Public Medicine University of Campania, Luigi Vanvitelli  Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Esposito","sequence":"additional","affiliation":[{"name":"Hematology Unit Ascalesi Hospital  Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Guastafierro","sequence":"additional","affiliation":[{"name":"Hematology Unit University of Campania, Luigi Vanvitelli  Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Siniscalchi","sequence":"additional","affiliation":[{"name":"Department of Medical, Surgical, Neurological, Metabolic and Aging Sciences University of Campania \u201cLuigi Vanvitelli\u201d  Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Macera","sequence":"additional","affiliation":[{"name":"Department of Mental Health and Public Medicine University of Campania, Luigi Vanvitelli  Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Boemio","sequence":"additional","affiliation":[{"name":"Department of Medical, Surgical, Neurological, Metabolic and Aging Sciences University of Campania \u201cLuigi Vanvitelli\u201d  Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Onorato","sequence":"additional","affiliation":[{"name":"Department of Mental Health and Public Medicine University of Campania, Luigi Vanvitelli  Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Rinaldi","sequence":"additional","affiliation":[{"name":"Department of Medical, Surgical, Neurological, Metabolic and Aging Sciences University of Campania \u201cLuigi Vanvitelli\u201d  Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Minichini","sequence":"additional","affiliation":[{"name":"Department of Mental Health and Public Medicine University of Campania, Luigi Vanvitelli  Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. 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