{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T18:32:11Z","timestamp":1789669931045,"version":"4.0.1"},"reference-count":36,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2018,6,13]],"date-time":"2018-06-13T00:00:00Z","timestamp":1528848000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Australian National Health and Medical Research Commission Early Career Fellowship","award":["APP1092621"],"award-info":[{"award-number":["APP1092621"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Viral Hepatitis"],"published-print":{"date-parts":[[2018,10]]},"abstract":"Summary<\/jats:title>In Taiwan, an outbreak of acute hepatitis A (AHA<\/jats:styled-content>) infection has been identified since June 2015. Approximately half of the cases occurred in HIV<\/jats:styled-content>\u2010infected men who have sex with men (MSM<\/jats:styled-content>). We used the Taiwan Centers for Disease Control (TCDC<\/jats:styled-content>)\u2010operated National Disease Surveillance Systems (NDSS<\/jats:styled-content>) to identify the incidence of AHA<\/jats:styled-content> during 2011\u20102016. Between June 2015 and December 2016, a total of 1268 AHA<\/jats:styled-content> cases were documented, and 601 cases (47.4%) were co\u2010infected with HIV<\/jats:styled-content>; the majority of whom were MSM<\/jats:styled-content> (98.4%). Each AHA<\/jats:styled-content> case was matched to two HIV<\/jats:styled-content>\u2010infected controls without AHA<\/jats:styled-content> reported in the NDSS<\/jats:styled-content> on age (\u00b1 5\u00a0years), risk factor of HIV<\/jats:styled-content> infection, HIV<\/jats:styled-content> diagnosis date (\u00b1 30\u00a0days) and county\/city of residence at HIV<\/jats:styled-content> diagnosis. Three hundred forty\u2010three HIV<\/jats:styled-content>\/AHA<\/jats:styled-content> cases were matched to 686 controls. In multivariable conditional logistic regression analysis, a previous gonorrhoea (adjusted OR<\/jats:styled-content>=1.77, 95% CI<\/jats:styled-content> 1.16\u20102.70) and recent (aOR<\/jats:styled-content>=6.77, 95% CI<\/jats:styled-content> 4.34\u201010.55) or remote syphilis report (aOR<\/jats:styled-content>=3.56, 95% CI<\/jats:styled-content> 2.48\u20105.13) were independently associated with AHA<\/jats:styled-content>. The epidemic persisted till December 2016, and the cases with a new diagnosis of HIV<\/jats:styled-content> infection after AHA<\/jats:styled-content> (28\/301, 9.3%) increased after July 2016 (P\u00a0<\/jats:italic>=\u00a0<\/jats:italic>.001). HIV<\/jats:styled-content>\/AHA<\/jats:styled-content> cases were centralized in northern and central metropolitan areas and HIV<\/jats:styled-content>\u2010infected MSM<\/jats:styled-content> with a recent history of sexually transmitted diseases in Taiwan. We recommend surveillance of associated behavioural and virologic characteristics and HAV<\/jats:styled-content> counselling and testing for HIV<\/jats:styled-content>\u2010infected men.<\/jats:p>","DOI":"10.1111\/jvh.12926","type":"journal-article","created":{"date-parts":[[2018,5,9]],"date-time":"2018-05-09T11:12:19Z","timestamp":1525864339000},"page":"1208-1215","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Epidemiological characteristics and associated factors of acute hepatitis A outbreak among HIV<\/scp>\u2010coinfected men who have sex with men in Taiwan, June 2015\u2010December 2016"],"prefix":"10.1111","volume":"25","author":[{"given":"C.\u2010Y.","family":"Cheng","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Taoyuan General Hospital, Ministry of Health and Welfare Taoyuan Taiwan"},{"name":"School of Public Health National Yang\u2010Ming University Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.\u2010H.","family":"Wu","sequence":"additional","affiliation":[{"name":"Division of Infection Control and Biosafety Centers for Disease Control Ministry of Health and Welfare Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Zou","sequence":"additional","affiliation":[{"name":"Kirby Institute University of New South Wales Sydney NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9675-770X","authenticated-orcid":false,"given":"Y.\u2010C.","family":"Lo","sequence":"additional","affiliation":[{"name":"Deputy Director\u2010General\u2019s Office Taiwan Centers for Disease Control, Ministry of Health and Welfare Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,6,13]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1086\/314518"},{"key":"e_1_2_9_3_1","first-page":"743","article-title":"Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990\u20102013: a systematic analysis for the Global Burden of Disease Study\u00a02013","volume":"2015","author":"Global Burden of Disease Study 2013 Collaborators","year":"2013","journal-title":"Lancet"},{"key":"e_1_2_9_4_1","unstructured":"Centres for Disease Control and Prevention (CDC).Epidemiology and Prevention of Vaccine\u2010Preventable Diseases hepatitis A.https:\/\/www.cdc.gov\/vaccines\/pubs\/pinkbook\/hepa.htmlAccessed July 30 2017"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1086\/318478"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1086\/338152"},{"key":"e_1_2_9_7_1","unstructured":"World Health Organization (WHO).Global health sector strategy on viral hepatitis 2016\u20102021.http:\/\/www.who.int\/hepatitis\/strategy2016-2021\/ghss-hep\/enAccessed July 30 2017"},{"key":"e_1_2_9_8_1","unstructured":"European Centre for Disease Prevention and Control.Epidemiological update \u2013 overview of hepatitis A in EU countries as of 1 August 2017.https:\/\/ecdc.europa.eu\/en\/news-events\/epidemiological-update-overview-hepatitis-eu-countries-1-August-2017Accessed December 23 2017"},{"key":"e_1_2_9_9_1","unstructured":"Centres for Disease Control and Prevention (CDC).Viral Hepatitis. 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