{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T16:57:40Z","timestamp":1790096260034,"version":"4.0.1"},"reference-count":33,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2020,9,24]],"date-time":"2020-09-24T00:00:00Z","timestamp":1600905600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100004337","name":"Roche","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004337","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007110","name":"Schering-Plough","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007110","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009060","name":"Sidaction","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009060","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Viral Hepatitis"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>There remains a substantial gap in our understandings of the life experiences of patients following HCV cure among HIV\u2010HCV\u2013co\u2010infected people who inject drugs (PWID) and men who have sex with men (MSM), two key populations targeted for HCV elimination. We described the experiences and perspectives of HIV\u2010positive PWID and MSM, HCV\u2010cured following treatment with direct\u2010acting antivirals (DAA). We used an exploratory sequential mixed approach using both qualitative data (semi\u2010structured interviews with 27 PWID and 20 MSM) and quantitative data (self\u2010administered questionnaires with 89 PWID) via the prospective ANRS CO13 HEPAVIH cohort. PWID reported improvements in physical health\u2010related quality of life (HRQL) and self\u2010reported symptoms following treatment, but no significant change in mental HRQL. During interviews, several MSM, more recently diagnosed with HCV, expressed less concern regarding HCV than HIV infection and interpreted improvements in their overall well\u2010being after HCV cure to be more related to a closer connection with healthcare providers than with viral elimination. By contrast, PWID, particularly those previously exposed to interferon\u2010based treatments, described major improvements in their physical HRQL. Both MSM and PWID reported improvements in cognitive or psychological wellbeing, and a majority of them reported some degree of concern over potential HCV reinfection. To conclude, though health benefits of HCV cure concern both groups, HIV\u2010infected PWID and MSM may have different representations and experiences following DAA treatment, related to their history with HCV. They are thus likely to benefit from holistic, post\u2010treatment follow\u2010up care that is responsive to their evolving health and social contexts.<\/jats:p>","DOI":"10.1111\/jvh.13378","type":"journal-article","created":{"date-parts":[[2020,8,27]],"date-time":"2020-08-27T22:20:49Z","timestamp":1598566849000},"page":"1462-1472","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Life after hepatitis C cure in HIV\u2010infected people who inject drugs and men who have sex with men treated with direct\u2010acting antivirals in France: Health perceptions and experiences from qualitative and quantitative findings (ANRS CO13 HEPAVIH)"],"prefix":"10.1111","volume":"27","author":[{"given":"Marion","family":"Mora","sequence":"first","affiliation":[{"name":"Aix Marseille Univ INSERM, IRD, SESSTIM Sciences Economiques &amp; Sociales de la Sant\u00e9 &amp; Traitement de l'Information M\u00e9dicale  Marseille France"},{"name":"ORS PACA Observatoire R\u00e9gional de la Sant\u00e9 Provence\u2010Alpes\u2010C\u00f4te d'Azur  Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trevor","family":"Goodyear","sequence":"additional","affiliation":[{"name":"British Columbia Centre on Substance Use  Vancouver BC Canada"},{"name":"School of Nursing University of British Columbia  Vancouver BC Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8853-3829","authenticated-orcid":false,"given":"Fabienne","family":"Marcellin","sequence":"additional","affiliation":[{"name":"Aix Marseille Univ INSERM, IRD, SESSTIM Sciences Economiques &amp; 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Sociales de la Sant\u00e9 &amp; Traitement de l'Information M\u00e9dicale  Marseille France"},{"name":"Ecole des Hautes Etudes en Sciences Sociales (EHESS) Institut de Recherche Interdisciplinaire Sur Les Enjeux Sociaux (Iris)  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3316-8785","authenticated-orcid":false,"given":"Philippe","family":"Sogni","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris Descartes  Paris France"},{"name":"INSERM U1223 Institut Pasteur  Paris France"},{"name":"Service d'H\u00e9patologie AP\u2010HP, H\u00f4pital Cochin  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2403-0960","authenticated-orcid":false,"given":"Linda","family":"Wittkop","sequence":"additional","affiliation":[{"name":"University of Bordeaux ISPED, Inserm Bordeaux Population Health Research Center Team MORPH3EUS, UMR 1219, CIC-EC 1401  Bordeaux France"},{"name":"CHU de Bordeaux Pole de sant\u00e9 Publique  Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7682-0115","authenticated-orcid":false,"given":"David","family":"Zucman","sequence":"additional","affiliation":[{"name":"Service de M\u00e9decine Interne H\u00f4pital Foch  Suresnes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5676-5411","authenticated-orcid":false,"given":"Isabelle","family":"Poizot\u2010Martin","sequence":"additional","affiliation":[{"name":"Aix Marseille Univ INSERM, IRD, SESSTIM Sciences Economiques &amp; 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