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We conducted a cross\u2010sectional study of New York City residents aged 18\u201029\u00a0years who reported non\u2010medical prescription opioid and\/or heroin use in the past 30\u00a0days. Participants were recruited from the community between 2014\u20102016 via respondent\u2010driven sampling. Participants completed an in\u2010person structured survey that included questions about HCV testing and treatment and received HCV antibody testing. There were 539 respondents: 353 people who inject drugs (PWID) and 186 non\u2010PWID. For PWID, median age was 25\u00a0years, 65% were male and 73% non\u2010Hispanic White. For non\u2010PWID, median age was 23\u00a0years, 73% were male and 39% non\u2010Hispanic White. 20% of PWID and 54% of non\u2010PWID had never been tested for HCV (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001). Years since first injection (aOR 1.16, CI: 1.02\u20101.32, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.02) and history of substance use treatment (aOR 3.17, CI: 1.53\u20106.61, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.02) were associated with prior testing among PWID. The seroprevalence of HCV among PWID was 25%, adjusted for sampling weights. Of the 75 who were aware of their HCV\u2010positive status, 53% had received HCV\u2010related medical care, and 28% had initiated treatment. HCV prevalence among young PWID is high, and many have never been tested. Injection experience and treatment engagement is associated with testing. Interventions to increase testing earlier in injection careers, and to improve linkage to HCV treatment, will be critical for young PWID.<\/jats:p>","DOI":"10.1111\/jvh.13437","type":"journal-article","created":{"date-parts":[[2020,11,3]],"date-time":"2020-11-03T18:05:01Z","timestamp":1604426701000},"page":"326-333","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Hepatitis C testing and treatment uptake among young people who use opioids in New York City: A cross\u2010sectional study"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6363-2839","authenticated-orcid":false,"given":"Shashi N.","family":"Kapadia","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases Weill Cornell Medicine New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Katzman","sequence":"additional","affiliation":[{"name":"Department of Medicine New York University School of Medicine New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunki","family":"Fong","sequence":"additional","affiliation":[{"name":"Institute for Implementation Science in Population Health City University of New York Graduate School of Public Health &amp; Health Policy New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin J.","family":"Eckhardt","sequence":"additional","affiliation":[{"name":"Department of Medicine New York University School of Medicine New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Honoria","family":"Guarino","sequence":"additional","affiliation":[{"name":"Institute for Implementation Science in Population Health City University of New York Graduate School of Public Health &amp; Health Policy New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro","family":"Mateu\u2010Gelabert","sequence":"additional","affiliation":[{"name":"Department of Community Health and Social Sciences City University of New York Graduate School of Public Health &amp; Health Policy New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,11,22]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.2017.304132"},{"key":"e_1_2_9_3_1","volume-title":"Viral Hepatitis Surveillance, 2016","author":"Centers for Disease Control and Prevention","year":"2017"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwn237"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2893.2009.01105.x"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/pubmed\/fds018"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jis927"},{"key":"e_1_2_9_8_1","unstructured":"New York City Deparment of Health and Mental Hygiene.Working Toward a Hep Free NYC \u2010 Hepatitis A B and C in New York City: 2018 Annual Report. 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