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In this PREVAIL study's secondary analyses, we explored the association between self\u2010reported and objective DAAs adherence among a sample of people who inject drugs (PWID) receiving medications for opioid use disorder (MOUD) (<jats:italic>N<\/jats:italic>\u00a0=\u00a0147). Self\u2010reported adherence was recoded 3 times during treatment (weeks 4, 8 and 12) using a visual analog scale (VAS), whereas objective adherence was collected continuously during treatment using electronic blister packs. Participants who reported being perfectly adherent had significantly higher blister pack adherence in each period (weeks 4, 8 and 12; <jats:italic>p<\/jats:italic>s\u00a0&lt;\u00a0.05) and over the 12\u2010week study (<jats:italic>p\u00a0<\/jats:italic>&lt;\u00a0.001) compared to those who reported being non\u2010perfectly adherent. Whites were more likely to report perfect adherence (91.7%) than Blacks (48.7%), Latinos (52.2%) and other (75.0%) race groups. Participants who reported recent use of cocaine (63.9%) or polysubstance use (60.0%) and those who had a positive result for cocaine (62.8%) were more likely to be non\u2010perfectly adherent, although none of these factors were associated with blister pack adherence. This study showed that the VAS could serve as a reliable option for assessing DAAs adherence among PWID on MOUD. The implementation of VAS may be an ideal option for monitoring adherence among PWID on MOUD, especially in clinical settings with limited resources. PWID on MOUD who are Black or other races than White, as well as those who report recent cocaine or polysubstance use may require additional support to maintain optimal DAA adherence.<\/jats:p>","DOI":"10.1111\/jvh.13445","type":"journal-article","created":{"date-parts":[[2020,11,29]],"date-time":"2020-11-29T17:50:45Z","timestamp":1606672245000},"page":"548-557","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Rates of perfect self\u2010reported adherence to direct\u2010acting antiviral therapy and its correlates among people who inject drugs on medications for opioid use disorder: The PREVAIL study"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5814-0397","authenticated-orcid":false,"given":"Irene","family":"Pericot\u2010Valverde","sequence":"first","affiliation":[{"name":"Clemson University School of Health Research Clemson University Clemson SC USA"},{"name":"Department of Internal Medicine Prisma Health Greenville SC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lior","family":"Rennert","sequence":"additional","affiliation":[{"name":"Department of Public Health Sciences Clemson University Clemson SC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moonseong","family":"Heo","sequence":"additional","affiliation":[{"name":"Department of Public Health Sciences Clemson University Clemson SC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4290-3083","authenticated-orcid":false,"given":"Matthew J.","family":"Akiyama","sequence":"additional","affiliation":[{"name":"Department of Medicine Albert Einstein College of Medicine Bronx NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8287-2245","authenticated-orcid":false,"given":"Briana L.","family":"Norton","sequence":"additional","affiliation":[{"name":"Department of Medicine Albert Einstein College of Medicine Bronx NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda","family":"Agyemang","sequence":"additional","affiliation":[{"name":"Department of Medicine Albert Einstein College of Medicine Bronx NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brandon","family":"Lumsden","sequence":"additional","affiliation":[{"name":"Department of Public Health Sciences Clemson University Clemson SC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6717-0288","authenticated-orcid":false,"given":"Alain H.","family":"Litwin","sequence":"additional","affiliation":[{"name":"Clemson University School of Health Research Clemson University Clemson SC USA"},{"name":"Department of Internal Medicine Prisma Health Greenville SC USA"},{"name":"Department of Medicine University of South Carolina School of Medicine Greenville SC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,12,9]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/14656566.2016.1182156"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciz1089"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/liv.14266"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugpo.2018.08.013"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11096-019-00917-0"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/prp2.379"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugpo.2017.05.025"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvh.13175"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.7326\/M18-1715"},{"key":"e_1_2_8_11_1","unstructured":"McLellanAT CacciolaJS ZanisD.The Addiction Severity Index\u2010Lite. 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