{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T03:37:24Z","timestamp":1792121844609,"version":"4.4.0"},"reference-count":40,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,3,3]],"date-time":"2021-03-03T00:00:00Z","timestamp":1614729600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003747","name":"Department of Health, State Government of Victoria","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003747","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Viral Hepatitis"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Hepatitis C virus (HCV) is more prevalent among people with experience of severe mental illness compared to the general population, due in part to higher levels of injecting drug use. Delivering HCV care through mental health services may reduce barriers to care and improve outcomes. A nurse\u2010led HCV program was established in a co\u2010located mental health and addiction service in Melbourne, Australia. People with a history of injecting drug use, including current use, were referred for HCV testing by nurses, with support provided on\u2010site from a general practitioner and remotely from infectious disease and hepatology specialists. A nurse practitioner, general practitioner or specialists were able to prescribe HCV treatment. One\u2010hundred and thirty people were referred to the nurse\u2010led service, among whom 112 (86%) were engaged in care. Of those 112, 84 (75%) were found to have detectable HCV RNA, 70 (83%) commenced treatment; 28 (40%) prescriptions were nurse initiated, 19 (27%) were general practitioner initiated and 20 (29%) were prescribed from hospital clinics or elsewhere. All people with an SVR result (48\/70) achieved HCV cure (intention to treat SVR 69%, per\u2010protocol SVR 100%). Treatment commencement was highest among people prescribed opioid agonist therapy (28\/29, 96%) compared to those who were not (18\/26, 69%). In conclusion, a nurse\u2010led, HCV service for people with severe mental illness including pathways to specialist support when needed can achieve high treatment uptake and cure. Further implementation work is required to improve treatment uptake, particularly among people not prescribed opioid agonist therapy, and to improve follow\u2010up for SVR testing.<\/jats:p>","DOI":"10.1111\/jvh.13487","type":"journal-article","created":{"date-parts":[[2021,2,18]],"date-time":"2021-02-18T07:17:12Z","timestamp":1613632632000},"page":"771-778","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Hepatitis C treatment in a co\u2010located mental health and alcohol and drug service using a nurse\u2010led model of care"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9288-6942","authenticated-orcid":false,"given":"Brendan L.","family":"Harney","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases Alfred Health and Monash University Melbourne Vic Australia"},{"name":"Disease Elimination Program Burnet Institute Melbourne Vic Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Brereton","sequence":"additional","affiliation":[{"name":"St Kilda Road &amp; Southcity Clinic Alfred Community Mental &amp; Addiction Health Melbourne Vic Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bradley","family":"Whitton","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Alfred Health and Monash University Melbourne Vic Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danusia","family":"Pietrzak","sequence":"additional","affiliation":[{"name":"St Kilda Road &amp; Southcity Clinic Alfred Community Mental &amp; Addiction Health Melbourne Vic Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma","family":"Paige","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Alfred Health and Monash University Melbourne Vic Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9015-7997","authenticated-orcid":false,"given":"Stuart K.","family":"Roberts","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Alfred Health Melbourne Vic Australia"},{"name":"Department of Medicine Monash University Melbourne Vic Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanne","family":"Birks","sequence":"additional","affiliation":[{"name":"St Kilda Road &amp; 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