{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T23:58:50Z","timestamp":1790812730707,"version":"4.1.0"},"reference-count":28,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,2,25]],"date-time":"2022-02-25T00:00:00Z","timestamp":1645747200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Viral Hepatitis"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>People living with HIV (PLHIV) are a priority population to receive hepatitis C virus (HCV) screening and treatment. We aimed to characterize the HCV care cascade among PLHIV between 2010 and 2018 and to compare HCV testing and treatment uptake pre\u2010 and post\u2010availability of direct\u2010acting antivirals (DAAs) in New South Wales (NSW), Australia. Records of all HCV notifications (1993\u20132017) were linked to HIV notifications, deaths, hospitalizations, incarcerations, opioid agonist therapy, HCV RNA testing and treatment databases. Numbers and proportions were calculated for all stages of the care cascade and factors associated with HCV testing, and DAA treatment uptake were evaluated using logistic regression. From 383 individuals with HCV notification (2009\u20132017), 349 (91%) were ever HCV RNA tested, 285 (74%) had an indicator of chronic HCV infection, and from those eligible for treatment, 210 (74%) received HCV treatment. HCV testing was recorded for 85% pre\u2010DAA era and reached a cumulative proportion of 90% post\u2010DAA while treatment uptake had a 10\u2010fold increase from 7% pre\u2010 to 73% post\u2010DAA era. Younger age (adjusted odds ratio [aOR] 0.98; 95% CI 0.96\u20130.99), female gender (aOR 1.87; 95% CI 1.10\u20133.19), and rural region residence at notification (aOR 1.56; 95% CI 1.03\u20132.36) were associated with not receiving HCV testing. No identified factor was associated with not receiving treatment post\u2010DAA era. Removing barriers to HCV testing, expanding treatment to a variety of settings and continuous education and harm reduction are essential to achieve HCV elimination among PLHIV in Australia.<\/jats:p>","DOI":"10.1111\/jvh.13658","type":"journal-article","created":{"date-parts":[[2022,2,17]],"date-time":"2022-02-17T16:54:55Z","timestamp":1645116895000},"page":"271-279","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Evaluation of the hepatitis C cascade of care among people living with HIV in New South Wales, Australia: A data linkage study"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8614-9129","authenticated-orcid":false,"given":"Samira","family":"Hosseini\u2010Hooshyar","sequence":"first","affiliation":[{"name":"The Kirby Institute UNSW Sydney Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4130-1358","authenticated-orcid":false,"given":"Maryam","family":"Alavi","sequence":"additional","affiliation":[{"name":"The Kirby Institute UNSW Sydney Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9444-0186","authenticated-orcid":false,"given":"Marianne","family":"Martinello","sequence":"additional","affiliation":[{"name":"The Kirby Institute UNSW Sydney Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8608-2558","authenticated-orcid":false,"given":"Heather","family":"Valerio","sequence":"additional","affiliation":[{"name":"The Kirby Institute UNSW Sydney Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shane","family":"Tillakeratne","sequence":"additional","affiliation":[{"name":"The Kirby Institute UNSW Sydney Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1048-6396","authenticated-orcid":false,"given":"Gail V.","family":"Matthews","sequence":"additional","affiliation":[{"name":"The Kirby Institute UNSW Sydney Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4741-2622","authenticated-orcid":false,"given":"Gregory J.","family":"Dore","sequence":"additional","affiliation":[{"name":"The Kirby Institute UNSW Sydney Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,2,25]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(15)00485-5"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1086\/321909"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.298.17.2028"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000000674"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2018.02.005"},{"key":"e_1_2_9_7_1","volume-title":"Global health sector strategy on viral hepatitis 2016\u20132021: towards ending viral hepatitis","author":"World Health Organization","year":"2016"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3018(15)00114-9"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1503153"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2018.02.006"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvh.12852"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciz985"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000002562"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/7355_2018_56"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/liv.14227"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2016.08.035"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciab526"},{"key":"e_1_2_9_18_1","volume-title":"HIV, viral hepatitis and sexually transmissible infections in Australia: annual surveillance report 2018","author":"The Kirby Institute","year":"2018"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1071\/SH19101"},{"key":"e_1_2_9_20_1","unstructured":"The New South Wales Health.Local health districts and specialty networks.2021[cited 2021 10\u2010Oct\u20102021]. 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