{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T16:18:30Z","timestamp":1788884310782,"version":"build-2803163510"},"reference-count":51,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2022,5,26]],"date-time":"2022-05-26T00:00:00Z","timestamp":1653523200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100002076","name":"Emergency Medicine Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100002076","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007619","name":"Society for Academic Emergency Medicine","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007619","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Viral Hepatitis"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The hepatitis C virus (HCV) treatment landscape is shifting given the advent of direct\u2010acting antivirals and a global call to action by the World Health Organization. Eliminating HCV is now an issue of healthcare delivery. Treatment is limited by the complexity of the HCV care continuum, expensive therapy and competing health burdens experienced by an underserved HCV population. The objective of this literature review was to assess strategies to improve retention in HCV care, with particular focus on those implemented in the United States. We identified barriers in HCV care retention and propose solutions to increase HCV treatment delivery. The following recommendations are herein described: improving the cohesion of health services through localized care and integrated case management, expanding the supply of non\u2010specialist HCV treatment providers, leveraging patient navigators and care coordinators, improving adherence through directly observed therapy and reducing cost barriers through value\u2010based payment and pharmaceutical subscription models.<\/jats:p>","DOI":"10.1111\/jvh.13685","type":"journal-article","created":{"date-parts":[[2022,5,12]],"date-time":"2022-05-12T08:04:43Z","timestamp":1652342683000},"page":"588-595","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Closing the hepatitis C treatment gap: United States strategies to improve retention in care"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0139-6807","authenticated-orcid":false,"given":"Austin T.","family":"Jones","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine Denver Health Medical Center  Denver Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Briones","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine University of California Los Angeles Medical Center  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Torrence","family":"Tran","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine University of California Los Angeles Medical Center  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Moreno\u2010Walton","sequence":"additional","affiliation":[{"name":"Section of Emergency Medicine Louisiana State University Health Sciences Center  New Orleans Louisiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia J.","family":"Kissinger","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, School of Public Health and Tropical Medicine Tulane University  New Orleans Louisiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,5,26]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"World Health Organization (WHO).Guidelines for the care and treatment of persons diagnosed with chronic hepatitis C virus infection.2018."},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.30297"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)32320-7"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2015.08.035"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41395-018-0061-4"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugpo.2019.102633"},{"key":"e_1_2_10_8_1","unstructured":"World Health Organization (WHO).Global Health Sector Strategy on Viral Hepatitis: 2016\u20132021.2016."},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.27584"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0101554"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cix163"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.30257"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/liv.14227"},{"key":"e_1_2_10_14_1","doi-asserted-by":"crossref","unstructured":"World Health Organization.Global Hepatitis Report 20172017. doi:10.1149\/2.030203jes","DOI":"10.1149\/2.030203jes"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0097317"},{"key":"e_1_2_10_16_1","unstructured":"AASLD\u2010IDSA Hepatitis C Guidance Panel.HCV guidance: recommendations for testing managing and treating hepatitis C.2021.https:\/\/www.hcvguidelines.org\/sites\/default\/files\/full\u2010guidance\u2010pdf\/AASLD\u2010IDSA_HCVGuidance_October_05_2021.pdf. Accessed March 2 2022."},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cit271"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.30501"},{"issue":"4","key":"e_1_2_10_19_1","first-page":"1","article-title":"Recommendations for the identification of chronic hepatitis C virus infection among persons born during 1945\u20101965","volume":"61","author":"Smith BD","year":"2012","journal-title":"MMWR Recomm Rep"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.14328"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1155\/2008\/949582"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cisl"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2015.02.022"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/5834182"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugpo.2017.05.056"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cis378"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.28810"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/jia2.25052"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(17)30284-4"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12913-019-4635-7"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1177\/1178633719841381"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.7326\/m17-0118"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1097\/PHH.0000000000000519"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/imj.14072"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1097\/ADM.0000000000000147"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1097\/PHH.0000000000000806"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10900-013-9663-3"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sapharm.2019.04.004"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2055-6640(20)30255-7"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0217471"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2008.02065.x"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvh.12857"},{"key":"e_1_2_10_44_1","unstructured":"WoolstonSL KimHN.Cost and access to direct\u2010acting antiviral agents. Hepatitis C Online.https:\/\/www.hepatitisc.uw.edu\/go\/evaluation\u2010treatment\/cost\u2010access\u2010medications\/core\u2010concept\/all. Published 2018. Accessed July 2 2020."},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13027-016-0071-z"},{"issue":"8","key":"e_1_2_10_46_1","first-page":"S131","article-title":"Assessing the burden of illness of chronic hepatitis C and impact of direct\u2010acting antiviral use on healthcare costs in Medicaid","volume":"25","author":"Roebuck MC","year":"2019","journal-title":"Am J Manag Care"},{"issue":"7","key":"e_1_2_10_47_1","article-title":"The First Hep C Value\u2010Based Bundled Payment Plan","volume":"28","author":"Hamm N","year":"2019","journal-title":"Manag Healthc Exec"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2018.1150"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.7326\/M18-0186"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMp1812959"},{"key":"e_1_2_10_51_1","article-title":"CMS approves WA value\u2010based purchasing plan for hepatitis C drugs","author":"Waddill K","year":"2019","journal-title":"HealthPayerIntelligence"},{"key":"e_1_2_10_52_1","unstructured":"Centers for Medicare & Medicaid Services.CMS approves Louisiana state plan amendment for supplemental rebate agreements using a modified subscription model for hepatitis C therapies in Medicaid.CMS.gov.https:\/\/www.cms.gov\/newsroom\/press\u2010releases\/cms\u2010approves\u2010louisiana\u2010state\u2010plan\u2010amendment\u2010supplemental\u2010rebate\u2010agreements\u2010using\u2010modified. Published 2019. Accessed July 2 2019."}],"container-title":["Journal of Viral Hepatitis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jvh.13685","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jvh.13685","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jvh.13685","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T13:31:53Z","timestamp":1692883913000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jvh.13685"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,26]]},"references-count":51,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2022,8]]}},"alternative-id":["10.1111\/jvh.13685"],"URL":"https:\/\/doi.org\/10.1111\/jvh.13685","archive":["Portico"],"relation":{},"ISSN":["1352-0504","1365-2893"],"issn-type":[{"value":"1352-0504","type":"print"},{"value":"1365-2893","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,26]]},"assertion":[{"value":"2021-12-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-05-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}