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By early diagnosis and immediate treatment of acute HCV infections, HCV micro\u2010elimination in MSM is within reach. In cooperation with the community affected, we developed an online HCV\u2010RNA home\u2010based self\u2010sampling test service. This service combined online HCV self\u2010risk assessment with the possibility to test anonymously for HCV\u2010RNA. The service was available in the Netherlands from February 2018 till December 2020 and was promoted online on various dating sites and offline by community volunteers. Using website user data, test results and an online post\u2010test user survey, we evaluated the service and user experiences. The website page with information about testing was visited by 3401 unique users, of whom 2250 used the HCV\u2010risk assessment tool, 152 individuals purchased 194 HCV\u2010RNA tests, and 104 tests were used, of which 101 gave a conclusive result. The target population of MSM at risk was successfully reached with 44.1% of users receiving the advice to test. The test service had a satisfactory uptake (6.8%, 152\/2250), a very high HCV\u2010RNA positivity rate (10.9%, 11\/101) and was considered acceptable and easy to use by most MSM.<\/jats:p><jats:p>We demonstrate that an HCV\u2010RNA home\u2010based self\u2010sampling test service is successful in diagnosing HCV infections among MSM. This service could be a valuable addition to existing sexual healthcare services as it may reach men who are otherwise not tested.<\/jats:p>","DOI":"10.1111\/jvh.13706","type":"journal-article","created":{"date-parts":[[2022,5,18]],"date-time":"2022-05-18T15:51:50Z","timestamp":1652889110000},"page":"677-684","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Internet\u2010guided <scp>HCV\u2010RNA<\/scp> testing: A promising tool to achieve hepatitis C micro\u2010elimination among men who have sex with men"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5894-5646","authenticated-orcid":false,"given":"Tamara","family":"Prinsenberg","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases, Amsterdam Infection and Immunity Institute, Amsterdam UMC University of Amsterdam  Amsterdam The Netherlands"},{"name":"Department of Infectious Diseases Research and Prevention Public Health Service of Amsterdam  Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janke","family":"Schinkel","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Amsterdam Infection and Immunity Institute, Amsterdam UMC University of Amsterdam  Amsterdam The Netherlands"},{"name":"Department of Medical Microbiology, Section of Clinical Virology, Amsterdam UMC University of Amsterdam  Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Zantkuijl","sequence":"additional","affiliation":[{"name":"Soa Aids Nederland  Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Udi","family":"Davidovich","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Research and Prevention Public Health Service of Amsterdam  Amsterdam The Netherlands"},{"name":"Department of Social Psychology University of Amsterdam  Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Prins","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Amsterdam Infection and Immunity Institute, Amsterdam UMC University of Amsterdam  Amsterdam The Netherlands"},{"name":"Department of Infectious Diseases Research and Prevention Public Health Service of Amsterdam  Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc","family":"van der Valk","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Amsterdam Infection and Immunity Institute, Amsterdam UMC University of Amsterdam  Amsterdam The Netherlands"},{"name":"HIV Monitoring Foundation  Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,5,28]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e32833c11a5"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2009.02.006"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/s2352-3018(20)30301-5"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/qad.0000000000003159"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2019.11.022"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/s2468-1253(20)30303-4"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/jia2.25348"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiz367"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-020-01835-z"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1586\/erm.10.101"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.2196\/19100"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0231385"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.Es.2017.22.21.30540"},{"key":"e_1_2_9_15_1","unstructured":"NoMoreC blood sampling instructions. 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