{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T02:18:13Z","timestamp":1787624293146,"version":"build-2736575974"},"reference-count":37,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,12,8]],"date-time":"2022-12-08T00:00:00Z","timestamp":1670457600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100005564","name":"Gilead Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005564","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006671","name":"Maryland Department of Health and Mental Hygiene","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006671","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000026","name":"National Institute on Drug Abuse","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Viral Hepatitis"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>There is a significant number of Emergency Department (ED) patients with known chronic hepatitis C virus (HCV) infection who have not been treated with directly acting antivirals. We implemented a pilot ED\u2010based linkage\u2010to\u2010care program to address this need and evaluated the impact of the program using the HCV Care Continuum metrics. Between March 2015 and May 2016, dedicated patient care navigators identified HCV RNA\u2010positive patients in an urban ED and offered expedited appointments with the on\u2010site viral hepatitis clinic. Patient demographics and care continuum outcomes were abstracted from the EMR and analysed to determine significant factors influencing linkage\u2010to\u2010care (LTC) and treatment initiation rates. The ED linkage\u2010to\u2010care program achieved a 43% linkage\u2010to\u2010care rate (165\/384), 22% treatment rate (84\/384) and 16% sustained virologic response rate (63\/384). Significant associations were found between linkage\u2010to\u2010care and increasing age (OR\u00a0=\u00a01.03), Medicare insurance (OR\u00a0=\u00a02.21) and having a primary care physician (PCP) (OR\u00a0=\u00a04.03). For patients who were linked, the odds of initiating treatment were also positively significantly associated with increasing age (OR\u00a0=\u00a01.04) and having a PCP (OR\u00a0=\u00a02.77). For patients who initiated treatment, the odds of sustained virologic response were marginally associated with having a PCP (OR\u00a0=\u00a04.92).Our ED linkage\u2010to\u2010care program utilized care coordination to successfully link nearly half of approached HCV RNA\u2010positive patients to care. This design can be feasibly replicated by other EDs given limited non\u2010clinical training required for linkage\u2010to\u2010care staff. Adoption of similar programs in other EDs may improve the rates of LTC and treatment initiation for previously diagnosed HCV patients.<\/jats:p>","DOI":"10.1111\/jvh.13774","type":"journal-article","created":{"date-parts":[[2022,11,28]],"date-time":"2022-11-28T17:28:55Z","timestamp":1669656535000},"page":"129-137","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Evaluation of a pilot emergency department linkage to care program for patients previously diagnosed with Hepatitis C"],"prefix":"10.1111","volume":"30","author":[{"given":"Zak","family":"Hyde","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine Johns Hopkins University School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ra\u00fal","family":"Roura","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Johns Hopkins University School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle","family":"Signer","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Johns Hopkins University School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anuj","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Johns Hopkins University School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacob","family":"Cohen","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Johns Hopkins University School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustapha","family":"Saheed","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Johns Hopkins University School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sherilyn","family":"Brinkley","sequence":"additional","affiliation":[{"name":"Division Infectious Diseases Johns Hopkins University School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5953-9316","authenticated-orcid":false,"given":"Risha","family":"Irvin","sequence":"additional","affiliation":[{"name":"Division Infectious Diseases Johns Hopkins University School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2145-6352","authenticated-orcid":false,"given":"Mark S.","family":"Sulkowski","sequence":"additional","affiliation":[{"name":"Division Infectious Diseases Johns Hopkins University School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David L.","family":"Thomas","sequence":"additional","affiliation":[{"name":"Division Infectious Diseases Johns Hopkins University School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard E.","family":"Rothman","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Johns Hopkins University School of Medicine  Baltimore Maryland USA"},{"name":"Division Infectious Diseases Johns Hopkins University School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1616-8014","authenticated-orcid":false,"given":"Yu\u2010Hsiang","family":"Hsieh","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Johns Hopkins University School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,12,8]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciw111"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.30297"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0239393"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.rr6902a1"},{"key":"e_1_2_11_6_1","unstructured":"World Health Organization.Combating Hepatitis B and C to Reach Elimination by 2030. 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The main road to build the second pillar of health system]","volume":"19","author":"Maciocco G","year":"2007","journal-title":"Ann Ig"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofy076"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.2017.303748"},{"issue":"12","key":"e_1_2_11_36_1","first-page":"e379","article-title":"Cost burden of hepatitis C virus treatment in commercially insured patients","volume":"25","author":"Lu CY","year":"2019","journal-title":"Am J Manag Care"},{"key":"e_1_2_11_37_1","volume-title":"National Viral Hepatitis Roundtable and Center for Health law and Policy Innovation of Harvard Law School","year":"2019"},{"key":"e_1_2_11_38_1","volume-title":"National Viral Hepatitis Roundtable and Center for Health law and Policy Innovation of Harvard Law School","year":"2022"}],"container-title":["Journal of Viral Hepatitis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jvh.13774","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jvh.13774","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jvh.13774","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T10:20:52Z","timestamp":1692440452000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jvh.13774"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,8]]},"references-count":37,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["10.1111\/jvh.13774"],"URL":"https:\/\/doi.org\/10.1111\/jvh.13774","archive":["Portico"],"relation":{},"ISSN":["1352-0504","1365-2893"],"issn-type":[{"value":"1352-0504","type":"print"},{"value":"1365-2893","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,8]]},"assertion":[{"value":"2022-09-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-11-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-12-08","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}