{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T14:50:46Z","timestamp":1770821446175,"version":"3.50.1"},"reference-count":40,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Viral Hepatitis"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In 2020, China conducted a nationwide, sero\u2010epidemiological, cross\u2010sectional survey of viral hepatitis. The stratified multi\u2010stage cluster random sampling method was used to select the permanent population aged 1\u201369\u2009years, followed by questionnaire survey and sample collection and detection of the serological markers of hepatitis B (HBV) and hepatitis C viruses (HCV). A total of 4747 individuals aged 1\u201369\u2009years were investigated in Zhejiang Province. The positive rates of hepatitis B surface antigen and anti\u2010HCV were 4.3% and 0%, respectively. Compared to a similar sero\u2010epidemiological survey in 1992, the 2020 survey showed that the HBV infection rate in Zhejiang Province decreased by 56.5%. In both surveys, HBV infection rate increased with age (in 1992, <jats:italic>\u03c7<\/jats:italic><jats:sup>2<\/jats:sup>\u00a0=\u00a0185.866, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.000; in 2020, <jats:italic>\u03c7<\/jats:italic><jats:sup>2<\/jats:sup>\u00a0=\u00a01383.836, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.000). Compared with 1992, the positive anti\u2010HCV rate in those aged 1\u201369\u2009years in 2020 decreased by 100.0%. This result showed that the HBV vaccine and blood screening to prevent HBV and HCV infection significantly decreased the infection rate of HBV and HCV in the younger generation of Zhejiang province. However, the rate of HBV carriers aged 30\u201369\u2009years was still high, which underscores the need to strengthen the management and treatment of chronic HBV infection. Hence, Zhejiang province can eliminate the public health threat of viral hepatitis.<\/jats:p>","DOI":"10.1111\/jvh.13820","type":"journal-article","created":{"date-parts":[[2023,2,20]],"date-time":"2023-02-20T14:54:00Z","timestamp":1676904840000},"page":"489-496","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["The infection rates of <scp>HBV<\/scp> and <scp>HCV<\/scp> decreased significantly in Zhejiang Province, China: A comparative study based on the data of two sero\u2010epidemiological surveys in 1992 and 2020"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4379-3456","authenticated-orcid":false,"given":"Yang","family":"Zhou","sequence":"first","affiliation":[{"name":"Department of Immunization Program Zhejiang Provincial Center for Disease Control and Prevention  Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Botao","family":"Zhao","sequence":"additional","affiliation":[{"name":"School of Public Health Xiamen University  Xiamen China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Microbiology Zhejiang Provincial Center for Disease Control and Prevention  Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaobei","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of AIDS and STD Control and Prevention Zhejiang Provincial Center for Disease Control and Prevention  Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liping","family":"Shen","sequence":"additional","affiliation":[{"name":"Department of Viral Hepatitis National Institute for Viral Disease Control and Prevention, China CDC  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of AIDS and STD Control and Prevention Zhejiang Provincial Center for Disease Control and Prevention  Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanqing","family":"He","sequence":"additional","affiliation":[{"name":"Department of Immunization Program Zhejiang Provincial Center for Disease Control and Prevention  Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,3]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"WHO.Hepatitis. 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