{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T16:38:58Z","timestamp":1791563938032,"version":"4.3.4"},"reference-count":64,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,8,26]],"date-time":"2025-08-26T00:00:00Z","timestamp":1756166400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Viral Hepatitis"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Chronic hepatitis B and C affect over 300 million people globally. Despite treatment advances, stigma towards people living with hepatitis B\/C (PLWHB\/C) remains a barrier to care and impacts health outcomes. Addressing this stigma is key to achieving hepatitis elimination goals. This systematic review aims to synthesise existing approaches to measuring stigma experienced by PLWHB\/C and examine factors associated with stigma in different social contexts. Databases searched included PubMed, PsycInfo and Web of Science, as well as grey literature (01\/01\/2008\u201330\/06\/2023). Studies were included if stigma experienced by or directed towards PLWHB\/C was measured quantitatively. Data from included studies were synthesised using a narrative approach. Among 3053 studies, 81 were included. Various tools were used to measure internalised (e.g., self\u2010blame, shame), enacted (e.g., experiences of discrimination) and anticipated stigma (e.g., expectations of discrimination) related to PLWHB\/C; most commonly the Toronto Chinese Hepatitis B Stigma Scale and Brener and Von Hippel's tool. Stigma was highly prevalent, impacting psychosocial wellbeing, treatment\u2010seeking behaviours and quality of life. Lower knowledge and conservative beliefs were linked to higher public stigma. Educational interventions and stigma\u2010reducing media showed some benefit in mitigating stigmatising attitudes. The review highlights stigma's pervasive nature and detrimental psychosocial impacts for PLWHB\/C globally. While diverse measurement tools were used, standardising culturally validated instruments aligned with conceptual frameworks could improve research. Tailored educational initiatives could help reduce stigmatising attitudes. Crucially, stigma hindered timely diagnosis and treatment access, emphasising the need for multi\u2010level interventions addressing stigma to achieve elimination goals.<\/jats:p>","DOI":"10.1111\/jvh.70064","type":"journal-article","created":{"date-parts":[[2025,8,26]],"date-time":"2025-08-26T11:27:14Z","timestamp":1756207634000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Global Systematic Review of the Measurement of Stigma Associated With People Living With Hepatitis B or Hepatitis C Viruses"],"prefix":"10.1111","volume":"32","author":[{"given":"Freddy","family":"Green","sequence":"first","affiliation":[{"name":"Blood Safety, Hepatitis, Sexually Transmitted Infections and HIV UK Health Security Agency  UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruth","family":"Simmons","sequence":"additional","affiliation":[{"name":"Blood Safety, Hepatitis, Sexually Transmitted Infections and HIV UK Health Security Agency  UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Leeman","sequence":"additional","affiliation":[{"name":"Blood Safety, Hepatitis, Sexually Transmitted Infections and HIV UK Health Security Agency  UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Desai","sequence":"additional","affiliation":[{"name":"Blood Safety, Hepatitis, Sexually Transmitted Infections and HIV UK Health Security Agency  UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1759-455X","authenticated-orcid":false,"given":"Matthew","family":"Hibbert","sequence":"additional","affiliation":[{"name":"Blood Safety, Hepatitis, Sexually Transmitted Infections and HIV UK Health Security Agency  UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,8,26]]},"reference":[{"key":"e_1_2_8_2_1","unstructured":"World Health Organisation \u201cHepatitis B Key Facts \u201d(2024) https:\/\/www.who.int\/en\/news\u2010room\/fact\u2010sheets\/detail\/hepatitis\u2010b."},{"key":"e_1_2_8_3_1","unstructured":"World Health Organisation \u201cHepatitis C Key Facts \u201d(2024) https:\/\/www.who.int\/news\u2010room\/fact\u2010sheets\/detail\/hepatitis\u2010c."},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(18)30056-6"},{"key":"e_1_2_8_5_1","unstructured":"World Health Organisation \u201cGlobal Health Sector Strategy on Viral Hepatitis 2016\u20132021 \u201d(2016)."},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2893.2011.01462.x"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/1467-9566.12018"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugpo.2021.103320"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2023.111013"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/liv.13189"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.14745\/ccdr.v44i78a03"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.4103\/2347-5625.195896"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2006.099150"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1071\/AH042720046"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/d41586-022-00816-x"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)68184-1"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.socscimed.2008.03.018"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-013-0437-9"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2010.02.007"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/jia2.25915"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2016-011458"},{"key":"e_1_2_8_22_1","first-page":"355","article-title":"ROBINS\u2010I: A Tool for Assessing Risk of Bias in Non\u2010Randomised Studies of Interventions","volume":"4919","author":"Sterne J. 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