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In countries like Australia, where most people with hepatitis B are born in countries with higher prevalence, it is important that the knowledge and perceptions of hepatitis B in immigrant populations are explored to improve engagement in care. This review sought to systematically identify and synthesise qualitative research findings describing the knowledge and perceptions of hepatitis B in immigrant communities. An Ovid database search for English language publications for the years 2000\u20132024 was performed. 34 studies were selected for review. These were analysed using thematic synthesis and categorised using an modified version of the socio\u2010ecological model. Ten analytic themes were identified: (1) knowledge of hepatitis B and misconceptions about transmission, (2) knowledge and familiarity with hepatitis B varies between communities, (3) culturally informed perceptions of health and illness, (4) alternative aetiologies of hepatitis B infection, (5) barriers and facilitators to engagement in healthcare, (6) sources of information, (7) stigma and family dynamics, (8) gender differences, (9) fear and anxieties of engaging with the healthcare system, (10) fear of health outcomes related to hepatitis B. These themes can be used to frame the development of culturally appropriate health promotion materials and interventions to improve knowledge and engagement in care among people living with hepatitis B.<\/jats:p>","DOI":"10.1111\/jvh.70069","type":"journal-article","created":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T06:28:51Z","timestamp":1757572131000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Knowledge and Perceptions of Hepatitis B in Immigrant Populations: A Systematic Review and Thematic Synthesis of Qualitative Research"],"prefix":"10.1111","volume":"32","author":[{"given":"Marvad","family":"Ahad","sequence":"first","affiliation":[{"name":"School of Public Health and Preventive Medicine Monash University  Melbourne Victoria Australia"},{"name":"Burnet Institute  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dina","family":"Moussa","sequence":"additional","affiliation":[{"name":"Burnet Institute  Melbourne Victoria Australia"},{"name":"The University of Melbourne  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4738-7316","authenticated-orcid":false,"given":"Jack","family":"Wallace","sequence":"additional","affiliation":[{"name":"Burnet Institute  Melbourne Victoria Australia"},{"name":"La Trobe University  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda J.","family":"Wade","sequence":"additional","affiliation":[{"name":"Burnet Institute  Melbourne Victoria Australia"},{"name":"Barwon Health  Geelong Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph S.","family":"Doyle","sequence":"additional","affiliation":[{"name":"School of Public Health and Preventive Medicine Monash University  Melbourne Victoria Australia"},{"name":"Burnet Institute  Melbourne Victoria Australia"},{"name":"Department of Infectious Diseases The Alfred Hospital  Melbourne Victoria Australia"},{"name":"School of Translational Medicine Monash University  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Howell","sequence":"additional","affiliation":[{"name":"School of Public Health and Preventive Medicine Monash University  Melbourne Victoria Australia"},{"name":"Burnet Institute  Melbourne Victoria Australia"},{"name":"The University of Melbourne  Melbourne Victoria Australia"},{"name":"St Vincent's Hospital  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,9,10]]},"reference":[{"key":"e_1_2_9_2_1","volume-title":"Global Hepatitis Report 2024: Action for Access in Low\u2010 and Middle\u2010Income Countries","author":"World Health Organization","year":"2024"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.32162"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.12688\/wellcomeopenres.14273.1"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2288-12-181"},{"key":"e_1_2_9_6_1","unstructured":"M.Ahad D.Moussa J.Wallace A.Wade J.Doyle andJ.Howell \u201cA Systematic Review and Thematic Synthesis of Qualitative Inquiries Into Knowledge and Perception of Hepatitis B Among Immigrant Populations \u201dPROSPERO 2023 CRD42023437041 https:\/\/www.crd.york.ac.uk\/prospero\/display_record.php?ID=CRD42023437041."},{"key":"e_1_2_9_7_1","unstructured":"Veritas Health Innovation \u201cCovidence Systematic Review Software \u201dwww.covidence.org."},{"key":"e_1_2_9_8_1","unstructured":"Critical Appraisal Skills Programme \u201cCASP Qualitative Studies Checklist [online] \u201d2024 https:\/\/casp\u2010uk.net\/casp\u2010tools\u2010checklists\/qualitative\u2010studies\u2010checklist\/."},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2288-8-45"},{"key":"e_1_2_9_10_1","unstructured":"QSR International \u201cNVivo 12 \u201d2023 https:\/\/lumivero.com\/products\/nvivo\/."},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.4159\/9780674028845"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/1355785042000222860"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.21518"},{"issue":"4","key":"e_1_2_9_14_1","first-page":"605","article-title":"Attitudes Toward Hepatitis B and Liver Cancer Prevention Among Chinese Americans in the San Francisco Bay Area, California","volume":"9","author":"Chang E. 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