{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T00:06:09Z","timestamp":1775433969338,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T00:00:00Z","timestamp":1773100800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T00:00:00Z","timestamp":1773100800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Viral Hepatitis"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>This study aimed to establish and evaluate a three\u2010tiered closed\u2010loop management model for hepatitis C involving \u2018CDC\u2010community\u2010follow\u2010up coordinators\u2019, so as to improve the referral rate and DAA treatment rate for previously diagnosed but untreated (DBU) patients, enhance the diagnosis and treatment coverage for in\u2010hospital HCV antibody\u2010positive patients, and accelerate the elimination of hepatitis C. In April 2024, the novel \u2018CDC\u2010community\u2010stationed follow\u2010up coordinators\u2019 model for hepatitis C management was launched in Nanhai District, Foshan City, with the CDC coordinating the recall of historical DBU patients; through government\u2010procured third\u2010party follow\u2010up services, stationed follow\u2010up coordinators were assigned to Nanhai District People's Hospital to facilitate the follow\u2010up, diagnosis and treatment of both in\u2010hospital patients and external DBU patients, while comparisons were conducted between pre\u2010 and post\u2010implementation periods regarding HCV RNA testing rates, DAA treatment rates and diagnosis\u2010to\u2010treatment delays, and treatment adherence and completion rates across different populations were assessed. A total of 4975 DBU patients between 2004 and 2024 were identified from the CDC database, and after 3 months of telephone follow\u2010up, the response rate was 38.21% (1901\/4975), the recall rate 23.55% (401\/1703), the HCV RNA positivity rate 25.69% (103\/401), and the DAA treatment rate 54.4% (56\/103). After the implementation of the model, the in\u2010hospital HCV RNA testing rate for anti\u2010HCV\u2010positive patients increased from 68.1% (738\/1084, January 2022\u2013March 2024) to 90.97% (393\/432, April\u2013December 2024), and the DAA treatment rate rose from 43.1% (116\/269, January 2022\u2013March 2024) to 76.7% (92\/120, April\u2013December 2024); the mean time from antibody positivity to RNA testing decreased from 19.3\u2009days to 11.0\u2009days, and the time from diagnosis to treatment initiation shortened from 42.2\u2009days to 22.6\u2009days. The CDC\u2010dispatching stationed follow\u2010up coordinator model enables effective link\u2010to\u2010care for DBU patients and significantly improves the diagnosis and treatment rates of in\u2010hospital HCV cases, demonstrating strong potential for scaling up in resource\u2010limited settings.<\/jats:p>","DOI":"10.1111\/jvh.70163","type":"journal-article","created":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T07:06:12Z","timestamp":1773126372000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A New Model for Hepatitis C Elimination: CDC\u2010Dispatching Follow\u2010Up Coordinators Stationed in Hospitals"],"prefix":"10.1111","volume":"33","author":[{"given":"Jingcheng","family":"Xu","sequence":"first","affiliation":[{"name":"Department of Infectious Disease, School of Medicine The Sixth Affiliated Hospital of South China University of Technology (Nanhai District People's Hospital of Foshan)  Foshan 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