{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T18:56:57Z","timestamp":1791313017716,"version":"4.3.1"},"reference-count":45,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Babesiosis in dogs is associated with severe thrombocytopenia; yet infected dogs rarely show clinical signs of hemorrhage.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Hypothesis<\/jats:title>\n                    <jats:p>Dogs with uncomplicated babesiosis have normal hemostatic capacity despite severe thrombocytopenia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals<\/jats:title>\n                    <jats:p>Nineteen client-owned dogs with uncomplicated babesiosis; 10 healthy controls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A prospective, cross-sectional, observational study. Thromboelastography (TEG), prothrombin time (PT), activated partial thromboplastin time (aPTT), fibrinogen, D-dimers, and antithrombin (AT) measured in both groups. Statistical significance set at P &amp;lt; .01.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Babesiosis group hematocrit and platelet count significantly lower than controls (0.29 versus 0.50 L\/L; P &amp;lt; .001 and 20.0 versus 374.5 \u00d7 109\/L; P &amp;lt; .001, respectively). Except for K, no significant difference in TEG variables between groups. Hemostatic variables for babesiosis group versus controls (mean \u00b1 SD); R: 5.9 \u00b1 1.8 versus 4.6 \u00b1 0.9 min (P = .048); K: 2.8 \u00b1 1.1 versus 1.9 \u00b1 0.6 min (P = .003); angle: 55.5 \u00b1 11.7 versus 62.2 \u00b1 4.1 degrees (P = .036); MA: 48.4 \u00b1 9.7 versus 57.2 \u00b1 5.2 mm (P = 0.013); G: 5.1 \u00b1 1.9 versus 6.9 \u00b1 1.5 dyn\/cm2 (P = .019); LY30 (median, range): 0 (0\u20135.7) versus 0.6% (0\u20136.1) (P = .152); and LY60: 0 (0\u20138.8) versus 3.1% (0\u201313.1) (P = .012). AT activity significantly lower (105.2 \u00b1 16.5 versus 127.8 \u00b1 15.4%; P = .001). Fibrinogen concentration significantly higher in babesiosis group (5.7 \u00b1 1.3 versus. 3.0 \u00b1 0.7 g\/L; P &amp;lt; .001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion and Clinical Importance<\/jats:title>\n                    <jats:p>Despite severe thrombocytopenia, dogs with uncomplicated babesiosis did not have clinical signs of hemorrhage and TEG variables were normal, which could indicate a normocoagulable state.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jvim.12016","type":"journal-article","created":{"date-parts":[[2013,1,11]],"date-time":"2013-01-11T14:34:36Z","timestamp":1357914876000},"page":"150-156","source":"Crossref","is-referenced-by-count":18,"title":["Hemostatic Abnormalities in Uncomplicated Babesiosis (\n                    <i>Babesia rossi<\/i>\n                    ) in Dogs"],"prefix":"10.1093","volume":"27","author":[{"given":"C.","family":"Liebenberg","sequence":"first","affiliation":[{"name":"University of Pretoria Department of Companion Animal Clinical Studies, , Pretoria,","place":["South Africa"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Goddard","sequence":"additional","affiliation":[{"name":"University of Pretoria Department of Companion Animal Clinical Studies, , Pretoria,","place":["South Africa"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Wiinberg","sequence":"additional","affiliation":[{"name":"Faculty of Life Sciences, University of Copenhagen Department of Small Animal Clinical Sciences, , Copenhagen,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Kjelgaard-Hansen","sequence":"additional","affiliation":[{"name":"Faculty of Life Sciences, University of Copenhagen Department of Small Animal Clinical Sciences, , 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