{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T16:18:50Z","timestamp":1770221930470,"version":"3.49.0"},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Fond de recherche clinique Pfizer"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Preoperative L-lactatemia and heart rate have been suggested as prognostic indicators of outcome for cows with right dilatation of the abomasum or volvulus (RDA\/AV). However, postoperative L-lactatemia has not been assessed as a potential prognostic tool.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To determine the prognostic value of postoperative L-lactatemia (LAC2), duration of treatment (Dt), relative L-lactatemia difference (compared with preoperative L-lactatemia [LAC1]) ([LAC2\u00a0\u2212\u00a0LAC1]\/LAC2) and change in L-lactate over time ([LAC2\u00a0\u2212\u00a0LAC1]\/Dt) as compared to preoperative findings (LAC1 and heart rate [HR]) as prognostic factors in dairy cows with RDA\/AV.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals<\/jats:title>\n                    <jats:p>A total of 41 dairy cows were included: 19 with AV and 22 with RDA; 11 cows had a negative outcome (NO) and 30 cows had a positive outcome (PO) based on telephone follow-up with owners 30\u00a0days after surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Prospective cohort study. Analysis was performed using logistic regression and comparison of area under the receiver operating characteristics curve (AUC) using nonparametric tests.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>LAC1\u00a0&amp;gt;\u00a01.4\u00a0mmol\/L or LAC2\u00a0&amp;gt;\u00a02.2\u00a0mmol\/L had the same accuracy with sensitivity of 100% (95% CI, 75.1\u2013100%) and specificity of 80% (95% CI, 61.4\u201392.3%) for predicting NO. The relative L-lactatemia difference ([LAC2\u00a0\u2212\u00a0LAC1]\/LAC1) or lactate kinetics ([LAC2\u00a0\u2212\u00a0LAC1]\/Dt) were not associated with prognosis. The AUC of the preoperative model (which included HR and lnLAC1) was 0.92 (95% CI, 0.83\u20131.0) and that of the postoperative model (including only lnLAC2) was 0.95 (95% CI, 0.88\u20131.0); these were not significantly different.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and Clinical Importance<\/jats:title>\n                    <jats:p>Postoperative L-lactatemia is helpful to predict outcome in cows with RDA\/AV. The short-term change in blood L-lactate is not a useful prognostic indicator, at least during the period of time spent on the farm for surgery and treatment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jvim.12490","type":"journal-article","created":{"date-parts":[[2014,10,10]],"date-time":"2014-10-10T11:48:10Z","timestamp":1412941690000},"page":"375-380","source":"Crossref","is-referenced-by-count":14,"title":["Preoperative and Postoperative L-Lactatemia Assessment for the Prognosis of Right Abomasal Disorders in Dairy Cattle"],"prefix":"10.1093","volume":"29","author":[{"given":"S.","family":"Buczinski","sequence":"first","affiliation":[{"name":"Facult\u00e9 de m\u00e9decine v\u00e9t\u00e9rinaire, D\u00e9partement des sciences cliniques, Universit\u00e9 de Montr\u00e9al , St-Hyacinthe, QC,","place":["Canada"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Boulay","sequence":"additional","affiliation":[{"name":"Facult\u00e9 de 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