{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T16:00:53Z","timestamp":1791302453922,"version":"4.1.0"},"reference-count":17,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"vor","delay-in-days":3261,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>A case study of renal tubular dysfunction consistent with idiopathic Fanconi syndrome is reported in an 18-month-old Holstein heifer. The clinical, biochemical, and histopathological features are described. The heifer had clinical signs of growth retardation, wasting, and persistent diarrhea. Biochemical blood analysis identified hypokalemia, hyponatremia, and hypochloremia. Urinalysis identified glycosuria, proteinuria, and acidic pH. Histological examination of the kidney disclosed mild tubular necrosis with proteinaceous casts in the lumina of renal tubules. We performed LC-HRMS on urine to confirm Fanconi syndrome. Using this technique, we identified severe generalized aminoaciduria suggestive of idiopathic renal Fanconi syndrome in this heifer.<\/jats:p>","DOI":"10.1111\/jvim.14605","type":"journal-article","created":{"date-parts":[[2017,1,21]],"date-time":"2017-01-21T07:08:20Z","timestamp":1484982500000},"page":"598-603","source":"Crossref","is-referenced-by-count":3,"title":["Aminoaciduria Caused by Fanconi Syndrome in a Heifer"],"prefix":"10.1093","volume":"31","author":[{"given":"N.","family":"Cesbron","sequence":"first","affiliation":[{"name":"Clinic for Ruminants, Oniris \u2013 Nantes-Atlantic National College of Veterinary Medicine, Food Science and Engineering , Nantes, Loire-Atlantique,","place":["France"]},{"name":"Laboratoire d'Etude des R\u00e9sidus et Contaminants dans les Aliments (LABERCA), INRA, Oniris \u2013 Nantes-Atlantic National College of Veterinary Medicine, Food Science and Engineering , Nantes, Loire-Atlantique,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Dorso","sequence":"additional","affiliation":[{"name":"Clinic for Ruminants, Oniris \u2013 Nantes-Atlantic National College of Veterinary Medicine, Food Science and Engineering , Nantes, Loire-Atlantique,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.-L.","family":"Royer","sequence":"additional","affiliation":[{"name":"Laboratoire d'Etude des R\u00e9sidus et Contaminants dans les Aliments (LABERCA), INRA, Oniris \u2013 Nantes-Atlantic National College of Veterinary Medicine, Food Science and Engineering , Nantes, Loire-Atlantique,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Dervilly-Pinel","sequence":"additional","affiliation":[{"name":"Laboratoire d'Etude des R\u00e9sidus et Contaminants dans les Aliments (LABERCA), INRA, Oniris \u2013 Nantes-Atlantic National College of Veterinary Medicine, Food Science and Engineering , Nantes, Loire-Atlantique,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Herv\u00e9","sequence":"additional","affiliation":[{"name":"Laboratoire d'Immuno-Endocrinologie Cellulaire et Mol\u00e9culaire, INRA, Oniris \u2013 Nantes-Atlantic National College of Veterinary Medicine, Food Science and Engineering , Nantes, Loire-Atlantique,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2017,3,1]]},"reference":[{"key":"2026020922041973700_jvim14605-bib-0001","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1038\/ki.1981.200","article-title":"The Fanconi syndrome and mechanisms of tubular transport dysfunction","volume":"20","author":"Roth","year":"1981","journal-title":"Kidney 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