{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T22:10:51Z","timestamp":1785535851842,"version":"3.56.0"},"reference-count":35,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"vor","delay-in-days":3261,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Ascending\/descending myelomalacia (ADMM) is a severe complication of thoracolumbar intervertebral disk herniation (TL-IVDH) in dogs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Hypothesis\/Objectives<\/jats:title>\n                    <jats:p>To investigate the prevalence and risk factors for ADMM in nonambulatory dogs with surgically treated TL-IVDH.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals<\/jats:title>\n                    <jats:p>Six-hundred and fifty-two client-owned dogs evaluated for TL-IVDH that underwent decompressive spinal surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective medical record review from February 2007 through December 2015.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Thirteen dogs developed ADMM, with an overall prevalence of 2.0%. The prevalence of ADMM was 0% in dogs with neurological signs graded 1 or 2 at admission or before magnetic resonance imaging (MRI) or surgical procedures, 0.6% in dogs with neurological signs graded 3, 2.7% in dogs with neurological signs graded 4, and 14.5% in dogs with neurological signs graded 5. Age (&amp;lt;5.8 years), neurological status (grade 5), site of disk herniation (L5-L6), duration of clinical signs before becoming nonambulatory (&amp;lt;24 hours), detection of intramedullary T2-weighted (T2W) hyperintensity, and a T2 length ratio &amp;gt;4.57 were significant risk factors in the univariate analysis for development of ADMM.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and Clinical Importance<\/jats:title>\n                    <jats:p>The factors identified in this study may be useful for the prediction of ADMM. Multicenter studies with a higher number of dogs with ADMM are required to confirm these data.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jvim.14656","type":"journal-article","created":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T02:33:36Z","timestamp":1485916416000},"page":"498-504","source":"Crossref","is-referenced-by-count":45,"title":["Prevalence and Risk Factors for Presumptive Ascending\/Descending Myelomalacia in Dogs after Thoracolumbar Intervertebral Disk Herniation"],"prefix":"10.1093","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9561-2477","authenticated-orcid":false,"given":"F.","family":"Balducci","sequence":"first","affiliation":[{"name":"Neurology Unit, Portoni Rossi Veterinary Hospital , Zola Predosa, 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