{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T05:50:46Z","timestamp":1791697846038,"version":"4.3.4"},"reference-count":37,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"vor","delay-in-days":3139,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Animal Health Foundation"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Repeatability of the oral sugar test (OST) has not been evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>We hypothesized that OST glucose, insulin, active (aGLP-1) and total (tGLP-1) glucagon-like peptide 1, and high-molecular-weight (HMW) adiponectin results would be repeatable.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals<\/jats:title>\n                    <jats:p>Fifty-three horses from a Tennessee research facility (n\u00a0=\u00a023) and private practice in Missouri (n\u00a0=\u00a030), including animals with medical histories of equine metabolic syndrome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Two OSTs were performed 7\u201314\u00a0days apart and plasma glucose and insulin concentrations were measured at 0, 60, and 75\u00a0minutes; a positive result was defined as detection of an insulin concentration &amp;gt;45\u00a0\u03bcU\/mL at 60 or 75\u00a0minutes. Plasma aGLP-1 and serum tGLP-1 concentrations at 75\u00a0minutes and serum HMW adiponectin concentrations at 0\u00a0minute were measured in the Missouri group. Bland-Altman analyses were performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>No adverse events were reported. Bland-Altman analysis indicated mean\u00a0\u00b1\u00a0SD bias of 1.5\u00a0\u00b1\u00a014.8\u00a0\u03bcU\/mL (95% confidence interval [CI], \u221227.6 to 30.5\u00a0\u03bcU\/mL) and 1.2\u00a0\u00b1\u00a016.1\u00a0\u03bcU\/mL (95% CI, \u221230.4 to 32.8\u00a0\u03bcU\/mL) for insulin concentrations at 60 and 75\u00a0minutes, respectively. There was 91 and 83% agreement in test interpretation between test days for OST insulin results for all horses in the Tennessee and Missouri groups, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and Clinical Importance<\/jats:title>\n                    <jats:p>Repeatability of the OST was acceptable when values obtained from Bland-Altman analyses were evaluated, and there was good agreement in binary (negative\/positive) test interpretation for insulin concentrations. However, wide 95% CIs were detected for insulin concentrations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jvim.14725","type":"journal-article","created":{"date-parts":[[2017,5,25]],"date-time":"2017-05-25T12:55:31Z","timestamp":1495716931000},"page":"1178-1187","source":"Crossref","is-referenced-by-count":43,"title":["Repeatability of Oral Sugar Test Results, Glucagon-Like Peptide-1 Measurements, and Serum High-Molecular-Weight Adiponectin Concentrations in Horses"],"prefix":"10.1093","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0564-7976","authenticated-orcid":false,"given":"N.","family":"Frank","sequence":"first","affiliation":[{"name":"Cummings School of Veterinary Medicine, Tufts University Department of Clinical Sciences, , North Grafton, MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.M.","family":"Walsh","sequence":"additional","affiliation":[{"name":"Homestead Veterinary Hospital , Pacific, 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